Conserved Protein Domain Family
Ribosomal_L50
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pfam10501: Ribosomal_L50 
Ribosomal subunit 39S
The 39S ribosomal protein appears to be a subunit of one of the larger mitochondrial 66S or 70S units. Under conditions of ethanol-stress in rats the larger subunit is largely dissociated into its smaller components. In E. coli, in the absence of the enzyme pseudouridine synthase (RluD) synthase, there is an accumulation of 50S and 30S subunits and the appearance of abnormal particles (62S and 39S), with concomitant loss of 70S ribosomes.
Links
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Statistics
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PSSM-Id: 402226
Aligned: 45 rows
Threshold Bit Score: 75.3908
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
EDK45407      107 DKVQLQGIVQKVYKDVLILDLKasaktdkpkfsdftlvdeiltqvggVERFEQYGLE--NLDLRFELVKKLQSSLGIELN 184 
XP_015788627  103 PREDVIECIKNIYMCYFTPKTEn------------------------DDDWLSQPLD--DMFTKFSFLSECDKQLEHEIP 156 
Q22623         94 PGVDVKNQVLEAASSCLRSAGVk------------------------SENVDQYKFVegDNSVKFELLNRLGKSIEHWPT 149  Caenorhabditi...
1_pfamImport    3 PSNNVKDQVLETASTCL---GVk------------------------ADSVSQYKFAdgDNSLKFELLTRLGKSIKHWPT 55  
EFO86175       93 PSNEVKNQVLKTASECLQKAGIs------------------------SENVEQYKFVegDNSLKFELINRLGKSIKHWPT 148 
XP_002631371   93 PSTGIKSQILETATECLQNAGVs------------------------SDNIEQYKFIdgDNSVKFELINRLGKSTKHWPT 148 
XP_007679865  250 lmSELEGAVAESASSAGNGALDatrn------------------vspARGWMEAPLK--DANIKMALYKRILQLTGKRIP 309 
EGS20002      274 WTPKFRASTAKKMVESWG------------------------------KEWKKAELR--DPVVKFYAAKRIQQLTGHRIP 321 
XP_013942248  241 SAEKISVEEAKEMIKSWD------------------------------PSWKNIAL---DNSLRFALRKRLYQLTGTLLP 287 
CEF76651      238 ERVEISADEAQQMVNALD------------------------------PSWKTVTLD--NDYLKFAIRKRLYQLTGHFIP 285 

EDK45407      185 DYTISKCHNLKDLYVEIeNVVNTRWK--WERNPNAIVLRKEDFT-APNIHLSEE 235 
XP_015788627  157 SPDLHLMKTVNDVVEFY--------RtpVRGLTTYDDLARRQNElPPNLNIINQ 202 
Q22623        150 NGKLLHLETVADVVEFY--------QtpVKNVTKYTEMARDENK-PKNVSIMEH 194  Caenorhabditis elegans
1_pfamImport   56 NGTLVHLETVADIVQFY--------QtpVKNVTKYTELARDETK-PKNVSILEQ 100 
EFO86175      149 NGKLLHLETVADVVKFY--------QepVKNITKYTEMARDETK-PKNVSIMEQ 193 
XP_002631371  149 NGRLLHLETVSDIVKFY--------EepVKNVTKYTEYARDENK-PKNVSIMEQ 193 
XP_007679865  310 DPVISTSTTIADLYNHL--RTKDKPAklFQSPQIQRLKVI-----APNVAVYSN 356 
EGS20002      322 DGKLHGYKTIEALLRHL--VDPPKAKklFEVVQQKGVFNE-----LPNVKVFPR 368 
XP_013942248  288 DAKLAAASTTKHILTLA--SRDPKPLklAQMLEKRNAFNE-----LTNVTVHDR 334 
CEF76651      286 DVKLAAAKTPRELIIVA-LTINKRGKklAEVLEEQKALTA-----LPNVTVHNR 333
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