3CUE,2J3T


Conserved Protein Domain Family
TRAPPC1_MUM2
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cd14855: TRAPPC1_MUM2 
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Trafficking protein particle complex subunit 1
Trafficking protein particle complex subunit 1 (TRAPPC1), also known as MUM2 and BET5, has been identified as a component of the transport protein particle (TRAPP), required for tethering endoplasmic reticulum (ER)-derived vesicles to Golgi membranes and for Golgi traffic.
Links
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Statistics
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PSSM-Id: 341445
Aligned: 49 rows
Threshold Bit Score: 144.612
Created: 15-Jan-2014
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
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Conserved site includes 22 residues -Click on image for an interactive view with Cn3D
Feature 1:TRAPPC4 interface [polypeptide binding site]
Evidence:
  • Structure:3CUE; Saccharomyces cerevisiae TRAPP complex, contacts 4A
  • Structure:2J3T; Human TRAPP I complex, contacts 4A
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1     #                                                                               
3CUE_C      4 YSFWIFDRHCNCIFDREWtlasnsasg----------------------------------------------------- 30  baker's yeast
EGF77862    3 YSLFIFNRHCACIFQTDWnkpstsktessdattgttigl----------------------------------------- 41  Batrachochytrium d...
EIE86448    4 YNLYIFDRHCQCIYFQKWshkaatpttsvtgtsttsqinnssrlgpltatttnsssrfsassanssshnatnttttgdnn 83  Rhizopus delemar R...
CCE84286    4 HSFYIFDRHCRCVYSREYtqgsdggs------------------------------------------------------ 29  Pichia farinosa CB...
CCJ29213    4 YKLFIFNRSCKSIYKKTWnnnrhletendnss------------------------------------------------ 35  Pneumocystis jirov...
CAH02131    3 YSLWIFDRHCNCIFDKEYtvnqstsi------------------------------------------------------ 28  Kluyveromyces lact...
EPY53381    4 YAFYIFSRKNECVFAHRWkpadsnsmetlv-------------------------------------------------- 33  Schizosaccharomyce...
EAL17742    4 FSLYIFDRHCDCVYYQDWhrtspvrppppasfkpgvhrlppapqptdtyrrs------------------ifdekrssgq 65  Cryptococcus neofo...
ESA43190    4 YSFYIFDRHTECIYSKTWlppppapgaqpqhdiststtgaavas----------------------------------sd 49  Neurospora crassa ...
EEB09617    4 YGFYIFDRHCECIYRQKWnqidvfsdsssavs------------------------------------------------ 35  Schizosaccharomyce...

Feature 1                             #  ##  #  ##  ## ####       ########                  # 
3CUE_C     31 ---------------tinskqneeDAKLLYGMIFSLRSITQKLSKGsvkndIRSISTGKYRVHTYCTASGLWFVLLSDFk 95  baker's yeast
EGF77862   42 ---srdtgaqsgglvgsidkqmeeTAKLVYGVVFSLRNIITKISPKqg-dnFISYRTNAYKLHYYESGTGLKFILLTDPn 117 Batrachochytrium d...
EIE86448   84 ssslvqsqtvqsglaagsvisieeEAKLVYGVILSLRNFVRKLSGSqd--gFISYKTSTYRLHYYETPTGLKFVMNSDPn 161 Rhizopus delemar R...
CCE84286   30 ----------------tnrsnesdTAKLMFGMLYSLKNIASKLGDKearnnLKSLSTGKFRLHLFETATGLRFVIVSDPa 93  Pichia farinosa CB...
CCJ29213   36 -----------mvhsqcntlnaddEAKLVFGVLYSLRRISKKLGGPdk--sFISYRTPEYKLHHYETASGLKFVLLTDPn 102 Pneumocystis jirov...
CAH02131   29 ----------------vnskeqqsRGKLIYGMVHSLKAMSTKIAPGn---tLRTLTTGKYRIHALFTASNLWIVIFSDLt 89  Kluyveromyces lact...
EPY53381   34 -------------sqlesatfeedVEKLIFGVIFSLRNMVRKISNGkd--dFLSYTTSQYKLHFYETPTNLRLVFFTSPk 98  Schizosaccharomyce...
EAL17742   66 astvdiksdglgsgralkglpfdeEAKLVYGVLISLRSMVKRLSGRdd-epFTSYTTPQYKLHLFETPTGYKFVLLSDPt 144 Cryptococcus neofo...
ESA43190   50 phhhnpntlrssrsavsaankasdDAKLIFGTVFSLRNMVRKLGGEdd--aFISYRTAQYKLHYYETASNLRFVMLTDTg 127 Neurospora crassa ...
EEB09617   36 ----------ndsskeksrstnndEEKLVFGVVFSLRNMVKKVAGNse--eFLSYSTSKYKLHFYETPSNIRMALLTSPn 103 Schizosaccharomyce...

Feature 1                                                                             
3CUE_C     96 qqsYTQVLQYIYSHIYVKYVSNNLlspydfaen---------------enemrgqgtRKITNRNFISVLESF 152 baker's yeast
EGF77862  118 sdnMVEVLRAIHAQIYVEYVSKNAllp----------------------------adGPINNELFRTNLLRF 161 Batrachochytrium dendrobat...
EIE86448  162 tenLKLVLKQIYIQLYVEFVVKNGlmrfddtrweisqgylqttentelqqqpitppsGNISNELFRIAVDRF 233 Rhizopus delemar RA 99-880
CCE84286   94 idnLQSVLWELYSNYYVRNVAQNAlspvd------------------------facdELLANPKFVSETDRF 141 Pichia farinosa CBS 7064
CCJ29213  103 cnnLLHVLHQIFVSLYVEFVVKNSlgnp-------------------------ecpkDDVEVELFELALDQF 149 Pneumocystis jirovecii
CAH02131   90 h-hELHERLDKIYELYLKYVVHNMlkpidlre------------------senakesDKITSPSFIKAVDQV 142 Kluyveromyces lactis NRRL ...
EPY53381   99 vepLTHVLHQIYATLYTEFVVKHPlytqvp----------------------pplekGGINCEMFRITLDRF 148 Schizosaccharomyces cryoph...
EAL17742  145 sdsLRFILRQLYMGPFLEYVVRNPlvkl-------------------------dsreEGIDNDQFRDAVDRH 191 Cryptococcus neoformans va...
ESA43190  128 tlsMRNVMHQIYINLWCEYVVKNPlapve------------------------hkggAGVRNELFELGLNQF 175 Neurospora crassa OR74A
EEB09617  104 venLVYVLHQVYATLYVEFVAKYPlysgk-----------------------skdfsVRIQNRLFDATLDRF 152 Schizosaccharomyces japoni...

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