Conserved Protein Domain Family
CaM-KIIN

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pfam15170: CaM-KIIN 
Calcium/calmodulin-dependent protein kinase II inhibitor
CaM-KIIN is the inhibitor of Calcium/calmodulin-dependent protein kinase II (CaMKII). CaMKII plays a central part in long-term potentiation, which underlies some forms of learning and memory. CaM-KIIN is a natural, specific inhibitor of CaMKII. This family is found in eukaryotes.
Statistics
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PSSM-Id: 373618
Aligned: 7 rows
Threshold Bit Score: 135.331
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
A5D7T0        1 MSEILPYSEDKMGRFGADPEGSDLSFSCRLQDTNSFFAGNQAKRPPKLGQIGRAKRVVIEDDRIDDVLKGMGEKPPSGV 79  cattle
XP_003975623  1 MSEVLPYSEGKMSGYGTDSEVSQMSFSCGLQDTSAFFAASQAKRPPKLGQIGRAKRVVIEDDRIDDVLKGMTDKSSPGV 79 
XP_005996807  1 MSEILPFSEEKMSRYGAETEVSQISFSCRLQDTNTFYGGPQAKRPPKLGQIGRAKRVVIEDDRIDDVLKGMTNKSSPGV 79 
Q0IHT1        1 MSEILPYSDEKMGHYGSDGDVGQISFSCRLQDTSSFFGGNQQKRPPKLGQIGRAKRVVIEDDRIDEVLKGVSDKSPSGV 79  tropical clawed frog
XP_005798033  1 MSEVLPFNEEKMSHYGNEGDEEHLSFTCRLQDTNNFFNGSQNKRPPKLGQIGRSKRVVIEDENGDEALKNGTEKTSgea 79 
1_pfamImport  1 ---VLPYGDEKLSPYDDCGDVGQI-FSCRLQDTTIFLSAGRTSSRPSWDQIWPEQAVVIEDDRIDDVLKNMTDKAPPGV 75 
A7MBG3        1 MSEVLPYGDEKLSPYGDGGDVGQV-FSCRLQDTNNFFGAGQNKRPPKLGQIGRSKRVVIEDDRIDDVLKNMTDKAPPGV 78  cattle
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