4UZZ,8BD7


Conserved Protein Domain Family
IFT52_CTD
?
cd23683: IFT52_CTD 
C-terminal domain of intraflagellar transport protein 52 (IFT52) and similar proteins
IFT52 is involved in ciliogenesis as part of a complex involved in intraflagellar transport (IFT), the bi-directional movement of particles required for the assembly, maintenance, and functioning of primary cilia. It is required for the anterograde transport of IFT88. IFT52 is a component of the IFT complex B that consists of a 9-subunit salt-stable core and several peripheral subunits. The model corresponds to the C-terminal domain of IFT52, which is responsible for binding to the C-terminal domain of IFT46.
Links
?
Statistics
?
PSSM-Id: 467897
Aligned: 114 rows
Threshold Bit Score: 54.8533
Created: 27-Apr-2023
Updated: 27-Apr-2023
Structure
?
Program:
Drawing:
Aligned Rows:
Download Cn3D
 
heterodimer
Conserved site includes 32 residues -Click on image for an interactive view with Cn3D
Feature 1:heterodimer interface [polypeptide binding site]
Evidence:
  • Structure:4UZZ; Tetrahymena thermophila IFT52 in complex with IFT46, contacts at 4A
Download Cn3D for Viewing 3D StructureScroll to Sequence Alignment Display
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection: 
Feature 1            #  #  # # ### ## #                   ## ##  #   # #         ##  ######### ###
4UZZ_B          1 GAASDEFASEKVRLAQLTNKCn---------------nNDLDYYIKESGDILGVTdkvknkhDAKAILRYVLEELINFKK 65   Tetrahymena t...
XP_018897228  363 YDLEEAFSSERSRLAQLANKClsskkid---ktheeevTDLEYFIKESAKILDVEnvn--sgSAQSILHSITLQIAEFKK 437  Bemisia tabaci
XP_975695     347 FDLDEAFSSVFSKLAQFTNKYtmttt--------kiddDDLEFYIKECSKIVKVEgq---mdGAASILHHMGEQIAKFKS 415  red flour beetle
XP_031328973  344 FDLDEAFSSSLTRLAQFTNKFlsttps------ndptdQQLDFYIQECAKIVNVGid---stDSKDILFEVATQCNKFKQ 414  common easter...
XP_002431439  347 FDLDEAFSSDKTRLAQITNKCmpkkedd---ddnydeeNNLIYYIQECTQIVRPYnditeysNPRQILHDLAVELREDPN 423  human body louse
XP_014271736  388 FDLQEEFYSETARLCQAANKAllyrskgsspvakeaeiEDVEYFVSECALVVGLGa-----gTAHSILNKIAIQLAQFKK 462  brown marmora...
XP_030764193  351 FDLDEAFSSVFSKLAQYTNKYitseld-----vndsdgKYLENFIVRCSKMIDGNst----dMAKDFLYNIGKDIADFKS 421  rice weevil
EDW76187      352 YDLDETFSPARSQLAHMTGQClqalqtke-psrralnqRELENYIKECARITAIVtee-qdmPAREILNIVARQIMSYKP 429  Drosophila wi...
KYN38428      348 FDLDEAFSSDLLKLSQITNKYmatke--------lsndKELDHYIREFGKMDLKTq-----sLPLARIKKIMKLDGDVKM 414  Trachymyrmex ...
KMQ97724      348 FDLNEAFSSDLLKLSQLTNKYmatkd--------lsnaKELDHYIREFGTERLRNlqe--dkHSKLTIGAFFEFMRTAYQ 417  Lasius niger

Feature 1         # 
4UZZ_B         66 LN 67   Tetrahymena thermophila
XP_018897228  438 NP 439  Bemisia tabaci
XP_975695     416 ID 417  red flour beetle
XP_031328973  415 NS 416  common eastern firefly
XP_002431439  424 AE 425  human body louse
XP_014271736  463 NL 464  brown marmorated stink bug
XP_030764193  422 ID 423  rice weevil
EDW76187      430 YA 431  Drosophila willistoni
KYN38428      415 IS 416  Trachymyrmex septentrionalis
KMQ97724      418 VN 419  Lasius niger

| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap