1MA3,1ICI


Conserved Protein Domain Family
SIR2

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COG0846: SIR2 
NAD-dependent protein deacetylase, SIR2 family [Posttranslational modification, protein turnover, chaperones]
Statistics
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PSSM-Id: 440607
Aligned: 783 rows
Threshold Bit Score: 109.48
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1MA3_A         1 MEd--------------------------------------eIRKAAEILAKSKHAVVFTGAGISAESGIPT-------F 35 
WP_012797280   1 MTpyeqlvvqltnqsfryqhvyrqggtpyrltekeplpyeeqIKAFAHMVEQADCILVGAASGLSAAGGGDFyyednesY 80 
WP_041736996 299 ML----------------------------------------INR----L-RAKQCVAITGSGIRk-GTLPD-------Y 325
WP_025391402   1 -------------------------------------mlvndYDAVLNIIKNSKTALFLTGAGMSADSGIPT-------F 36 
WP_128465557   1 ------------------------------------------MNKAVDIICGSRSCLFLTSAGMSAESGIPT-------F 31 
WP_044617906   1 MQsln----------------------------------qqlAVKVKALLNECDAVLIGAGAGLTSAAGIDYwde--qaF 44 
WP_126512435   1 MTwkaie------------------------------leennAEKLAQLIDEAEAIVIGIGAGMSAADGFTYig---erF 47 
WP_013669810   1 MSdketvwqa------------------------lsqnynneSGLLRALMEEAQAILVGIGAGMSAADGFTYvg---erF 53 
WP_013681304   1 -------------------------------------mkvndFGILEERIKNAESCLFLTSAGMSADSGIPT-------F 36 
WP_118991032   1 MSivwdsfk---------------------------qeglseGALLGSLIQEADAVVVGIGAGMSAADGFKYig---erF 50 
1MA3_A        36 RG--EDgLWRKy--------DPE-EV--ASISGFKRN-PRA---FWEfsMEMKDK--Lf-AEPNPAHYAIAELERMg-IV 94 
WP_012797280  81 RAyfGK-FAEKy--------GFQ-GA--FAGMMHPWEtAEE---RWGylATFLNTt-Ls-VPVRQPYVDLDAVIRD--KE 141
WP_041736996 326 PSg----QWl----------DPKvPItsYTLAEFKAS-KRCrylYWKasYDYYQQa-Lt-INKNNIDEQLDYLLNH--YL 386
WP_025391402  37 RD--KEgYWRNfpvfkekglEAQ-EL--ASPYSFEVR-PQY---AWAfyEWRRRN--AyyNKPHEGYYVIVRLMKEvfKS 105
WP_128465557  32 RD--KEgYWRNfpayknlnlEAV-EL--ANPRSFKTR-PAH---AWAfyEWRRRN--AreNKPHEGYSVINSLIDNhfEN 100
WP_044617906  45 ARifPG-WI-Kr--------GFT-AQ--YQLMGYSHWsQEE---QWGyyKTHLDYvyFs-QQSNPLYQSLYQLVKD--KD 105
WP_126512435  48 TSnfKD-FVEKy--------KFL-DM--LQASLFDFPsSQE---YWAfqSRFVLLnyFd-QPVGDSYLALKNILKD--KN 109
WP_013669810  54 EQafPD-FIEKf--------NLF-DM--LQASLYDYPsLEE---YWAfaSRFAIMngIe-QEAGKAYQHFNQYLQG--KN 115
WP_013681304  37 RD--KEgYWRNfpvfkrlglNAI-DL--ANPYSFEVR-PQY---AWAfyEWRRRN--AhqNKPHLGYHIINRLIKEvfKK 105
WP_118991032  51 NEafPD-FIEKy--------GLL-DM--LQAFLYNFEsIEE---YWAfqSRFVAMnyLd-QPVGPSYVNLKEMLEG--KP 112
1MA3_A        95 KAVITQNIDMLHQRAG--SRRVLELHGSMDKLDCLD---CHETY-DwSEFv------EDF----N-K--------GEIPR 149
WP_012797280 142 FFILTTNQDTQFMKLy-pWDKVAEIQGDHRFFQCQHc--CTDEVwDaTEPv------AKMi---EgMgeglavpaDLVPR 209
WP_041736996 387 SGLFTETVDSLFNTE---QHPVYECYGSIKRLYCLD---CAKQQ-AwPP----------------------------IPL 431
WP_025391402 106 SFIHTTNTDGYHLRSGadKDKVYEVHGSMWRLQCTRglaCSYFVqEnYDVplcdldeKTMq-----A--------SNLPY 172
WP_128465557 101 SFIHTTNTDGFHMISGtsADHVYEIHGSIWRLQCMAglgCSYTYeEnDDVplcgldcESMt-----A--------SNLPV 167
WP_044617906 106 YFVMTSNVDGHFYKNGfdKSRIYAPQGDYGLIQCTQp--CTKQVwEiKPFl------DQMhpyyDaReqil-tsaLGIPK 176
WP_126512435 110 YHIITTNADNAFDVAGydMDKVFHIQGKYRLMQCSKh--CHAKTyQdEALm------RRLa---VeQenme-vdyRSIPL 177
WP_013669810 116 YFIITTNADNAFPKAGydMDKVHYYQGKYVLMQCKKh--CQPVTyRdDALl------YRMa---KdQenmr-ipsELVPY 183
WP_013681304 106 SFVHTTNTDGYHIISGleESLVYEVHGSMWRLQCMRgysCEYKVkEnRDVplcdldyETMi-----A--------SNLPK 172
WP_118991032 113 YHVITTNADNAFYAAEydMDKVFYKQGEYGLFQCSKq--CHQQTyQdHDLl------REMv---ErQenmk-vpsELIPY 180
1MA3_A       150 -------CRKCGSyYVKPRVVLFGE-PLPQ------RTLFEAIE----EAKH-CD---AFMVVGSSLVVYPAAELP--YI 205
WP_012797280 210 -------CPHCGG-EAFPWVRGYGN-FLQG------ELYDEQYRkvsdWLSEhAQekvLFIELGVGRMTPAFIQEPfwAL 274
WP_041736996 432 wsqrdlhCQHCSG-LLKPQILAADE-NIDS------ECYQALQK----NMME-CG---CLLVIGVPTITPVVSMII--EN 493
WP_025391402 173 -------CPVCGS-LLRPNILMFGD-WDYIeneyqaNNYYEFIN----ECKY-PD---IIFLIGSSGAVPTNDYIA--NK 233
WP_128465557 168 -------CPKCGG-LLRPNVLMFGD-FDYVehayqyNNFRDFLE----RAGI-PD---VTLLIGSSGSVPTNDYLA--LR 228
WP_044617906 177 -------CPVCGS-DMFIHVRIDAS-FIDD------VHELERQAlf-dWLAAqERkrvLLIDLGSGFNTPTVIRLPmeKL 240
WP_126512435 178 -------CPECGA-PLEVNKRNAEKgMVED------PIFFEHLDkyneFLENnRDkktLFIEIGVGFTTPQFIKYPfyRE 243
WP_013669810 184 -------CPNCGA-PLELNKRTAENgMVED------KDWQVHQAayedFVKEnQYdkiLYLEIGVGNTTPQFIRQPfqAW 249
WP_013681304 173 -------CPHCGE-LLRPNILMFGD-WGYVeneyqiRNYNTFVD----DVGV-PD---LIFLIGSSSAVPTNDYLA--IR 233
WP_118991032 181 -------CPECGA-PLEINKRDAETgMVED------ADFKAQEAryeaFLKEvAGqkvLYLEIGVGHTTPQFIKHPfqEM 246
1MA3_A       206 A-KKAGAKMIIVNAEPT-MA-DPIF-D--VKIIGKAGEVLPKI---VE 244
WP_012797280 275 VsQLPQASYVGINNVTQ-FLpEVIE-DrgIAIRGDIAEVLTDV---RA 317
WP_041736996 494 A-NANKIPIIFIGTIPFgYFvEEk--D--VQLTGDIAHWLAEIngfIN 536
WP_025391402 234 F-KFYGSKIITINPAIE-ST-NICKpH--IFLQEKAKNALLNI---AS 273
WP_128465557 229 L-QASGSRIITINPDES-SL-KVCKpD--VFIQTGAKEALAAI---AD 268
WP_044617906 241 TiTLADATLVRVNLDHA-NTtLDLG-NkvISVQSDIAEFIKNI---SI 283
WP_126512435 244 LdKNPNALMITMNQKKY-QFpERIA-SrvLWFNQNSKDLTLDV---EE 286
WP_013669810 250 TkENPKALYVMMNQKPY-HIpPSIK-SqsLRLTDDIQKTLCEL----- 290
WP_013681304 234 F-QSKGSFVITINPDLS-ST-AVCKpD--LFIQKKAKESFEII---QR 273
WP_118991032 247 TaANEDALFVTMNAKNY-RIpQAIK-ErtVHLKGDIAQNIQEA---HE 289
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