Q98257 458 EGPFATSSELTDALAQMLAAQPEgvvlfyargsrsgadlklkrdntvdqavnviyrymssepvifgdgvtflefkrfsnd 537 Molluscum contagiosu... O74880 52 YNRHENNGNAQDVVRSHYNARPD--------------------------------------------------------- 74 Schizosaccharomyces ... P32783 109 EMTANRSINVDQIVREHYNERTI--------------------------------------------------------- 131 Saccharomyces cerevi... Q5ADX5 137 RISNRENRDINSIVRAHYNQRTQ--------------------------------------------------------- 159 Candida albicans SC5314 Q9LHQ7 30 FLEDETTKNFARKVADHYSRRTNq-------------------------------------------------------- 53 thale cress P25950 348 EGPFESHSEIIDLLTTYLPSQPEgvvlfysdqrnqpdykikldnttdhminiiyrymssepvifgenstfleykkfsd-d 426 Rabbit fibroma virus... P0DSX5 353 EGPFTTTSEVVDMLSTYLPKQPEgvilfyskgpksnidfkikkentidqtvnvvfrymssepiifgessifieykkftnd 432 Variola virus human/... Q9VJQ4 72 ETEAASGAANTHVVAHHYNELKE--------------------------------------------------------- 94 fruit fly Q9D0L8 125 QKLQKLEEGHSSAVAAHYNELQE--------------------------------------------------------- 147 house mouse Q28FT4 66 skrpRLEEGHGSLVVTHYNELPE--------------------------------------------------------- 88 tropical clawed frog
Q98257 538 kgfpkefgtgrlvlaegarylnniyclefadthsgvglrkvvvpvkfvgefshDGrlLRPRLAKTMLYLSNanyygnqas 617 Molluscum contagiosu... O74880 75 -----------------------------------------------------LG--YKKRQFSPIIQLKR--------- 90 Schizosaccharomyces ... P32783 132 -----------------------------------------------------IAn-RAKRNLSPIIKLRN--------- 148 Saccharomyces cerevi... Q5ADX5 160 -----------------------------------------------------QAkqQGSRVNSPIYKMRN--------- 177 Candida albicans SC5314 Q9LHQ7 54 --------------------------------------------------------tLEEREASPIIHLKK--------- 68 thale cress P25950 427 kgfpkdygtgklmltdnvrylnniyciaftnvyedvgiknvvvpikfisefsaTGelIKPRIDKTFKYLYKeyygnqyqi 506 Rabbit fibroma virus... P0DSX5 433 kgfpkeygsgkivlyngvnylnniycleyinthnevgiksvvvpikfiaeflvNGeiLKPRIDKTMKYINSedyygnqhn 512 Variola virus human/... Q9VJQ4 95 -----------------------------------------------------AG--RKDRQKSKIFFMRN--------- 110 fruit fly Q9D0L8 148 -----------------------------------------------------VG--LAKRSQSRIFYLRN--------- 163 house mouse Q28FT4 89 -----------------------------------------------------TG--LETRSQSRIFHLRN--------- 104 tropical clawed frog
Q98257 618 vvlehlqdqrlrvgdvfredkladagkaaavadahrlnpdtayftkrrvrgplgvLSNYVKTLLISLYCSKTFFdn--pN 695 Molluscum contagiosu... O74880 91 -------------------------------------------------------FNNWIKSVLIQKFAPHASD-----Y 110 Schizosaccharomyces ... P32783 149 -------------------------------------------------------FNNAIKYMLIDKYTKPGDV------ 167 Saccharomyces cerevi... Q5ADX5 178 -------------------------------------------------------FNNAIKYILLGNWAKHNPEe---lD 199 Candida albicans SC5314 Q9LHQ7 69 -------------------------------------------------------LNNWIKSVLIQLYARPDDA------ 87 thale cress P25950 507 vvahirdqnikigdvldedkls--dvgqhyandkyrlnpdvsyftnkrtrgplgiLSNYVKTLLISLYCSKTFLdn--sN 582 Rabbit fibroma virus... P0DSX5 513 vivehlrdqsikigdvfnedklsdvghqyanndkfrlnpevsyftnkrtrgplgiLSNYVKTLLISMYCSKTFLdd--sN 590 Variola virus human/... Q9VJQ4 111 -------------------------------------------------------FNNWIKSQLINEYMSQIKQnkrmgD 135 fruit fly Q9D0L8 164 -------------------------------------------------------FNNWIKSILIGEILEKVRQrk--tR 186 house mouse Q28FT4 105 -------------------------------------------------------FNNWMKSALIGEFVEKVRQr---tR 126 tropical clawed frog
Q98257 696 KRKVLAVDFGNGADLEKYFYGEIALLIATDPDARAIECGRERYnk-----lNSGNKSkyykFDYiqETIRSESFVASVRE 770 Molluscum contagiosu... O74880 111 PILVLDMGCGKGGDLIKWDKAGIDGYIGIDIAEVSVNQAKKRY--------REMHAS----FDA--LFYAGDCFSSSINE 176 Schizosaccharomyces ... P32783 168 ---VLELGCGKGGDLRKYGAAGISQFIGIDISNASIQEAHKRY--------RSMRNLd---YQV--VLITGDCFGESLGV 231 Saccharomyces cerevi... Q5ADX5 200 LFSFLDLCCGKGGDLNKCQFIGIDQYIGIDIADLSVKEAFERYtkqkarfrHSNQNSnrytFEA--CFATGDCFTQFVPD 277 Candida albicans SC5314 Q9LHQ7 88 ---VLDLACGKGGDLIKWDKARIGYYVGIDIAEGSIEDCRTRYngdadhhqRRKKFS----FPS--RLLCGDCFEVELDK 158 thale cress P25950 583 KRKVLAIDFGNGADLEKYFYGEISSLVATDPDKEAIGRCIERYns-----lNSGIKSkyykFDYiqETIRSVTYVSSVRE 657 Rabbit fibroma virus... P0DSX5 591 KRKVLAIDFENGADLEKYFYGEIALLVATDPDADAIARGNERYnk-----lNSGIKTkyykFDYiqETIRSNTFVSSVRE 665 Variola virus human/... Q9VJQ4 136 ALRVLDMCCGKGGDLLKWEKAAISHLICTDIAEVSVEQCQRRYqdi---lqRSEKSKfankFTA--EFFACDSTLVRLRE 210 fruit fly Q9D0L8 187 DITVLDLGCGKGGDLLKWRKGRISRLVCADIADISMKQCQQRYedm---rcRRDNEHi---FSA--EFITADCSKELLVE 258 house mouse Q28FT4 127 NIAVLDLGCGKGGDLLKWRKGGISKLVCTDIADVSVKQCEERYkdl---krKSRNERv---FEA--EFLTADSTKELLSE 198 tropical clawed frog
Q98257 771 VF---------YFGKFDIVDWQFAIHYSFHPRHYA-TVMRNLAELTASGCRVLITTVDGDFLatltR-KRSFVIHRDLPE 839 Molluscum contagiosu... O74880 177 LLp-------pDQRKFDVVSLQFCMHYAFESEEKVrVLLGNVSKCLPRGGVMIGTIPNSDVI----V-KHIKMLKPGEKE 244 Schizosaccharomyces ... P32783 232 AVepf----pdCRFPCDIVSTQFCLHYAFETEEKArRALLNVAKSLKIGGHFFGTIPDSEFIryklN-KFPKEVE--KPS 304 Saccharomyces cerevi... Q5ADX5 278 ILepnfpgiieRAFPVDIVSAQFSLHYSFESEEKVrTLLTNVTRSLRSGGTFIGTIPSSDFIkakiVdKHLQRDEKGKAK 357 Candida albicans SC5314 Q9LHQ7 159 ILe--------eDAPFDICSCQFAMHYSWTTEARArRALANVSALLRPGGVFIGTMPDANVI----I-KKLREAE--GLE 223 thale cress P25950 658 VF---------FFGKFDLVDWQFAIHYSFHPKHYA-TVMNNLTELTASGGKVLITTMDGDLLsqltD-KKTFVIHKNLPS 726 Rabbit fibroma virus... P0DSX5 666 VF---------YFGKFNIIDWQFAIHYSFHPRHYA-TIMNNLSELTASGGKVLITTMDGDKLskltD-KKTFIIHKNLPS 734 Variola virus human/... Q9VJQ4 211 RYk-------dPSLQLNLVSCQFAFHYCFESMAQAdCMMRNAAECLKPGGFFIATMPDAYEI----I-RRLRAAGPDARR 278 fruit fly Q9D0L8 259 KFr-------dPEMYFDVCSCQFACHYSFESQVQAdTMLRNACGRLNPGGYFIGTTPNSFEL----I-RRLEAS--ETES 324 house mouse Q28FT4 199 KYn-------dPEIKFDICSCQFVYHYSFETYEQAdMMLRNACERLCPGGFFIGTTPDGFEL----V-KRLEAS--DTNS 264 tropical clawed frog
Q98257 840 PENYISFEKLDSEHVLV--------------YNPSTMAKPMVEYIVRKQALVRVFGEYGFVLVDHVDFHTVVHRS----- 900 Molluscum contagiosu... O74880 245 WGNDIYKVRFPESPPRSfrppy----giqyyFYLEDAVTDVPEYVVPFEAFRAVAEGYNLELIWVKPFLDILNEEknset 320 Schizosaccharomyces ... P32783 305 WGNSIYKVTFENNSYQKndyeftspygqmytYWLEDAIDNVPEYVVPFETLRSLADEYGLELVSQMPFNKFFVQEipk-w 383 Saccharomyces cerevi... Q5ADX5 358 FGNSLYSVTFEKDPPEDgvfrpa--fgnkynYWLKDAVDNVPEYVVPFETLRSLCEEYDLVLKYKKSFTDIFNQEipk-y 434 Candida albicans SC5314 Q9LHQ7 224 IGNSVYWIRFGEEYSQKkfksssp-fgieyvFHLEDAV-DCPEWIVPFNVFKSLAEEYDLELVFVKNSHEFVHEYmkkpe 301 thale cress P25950 727 SENYMSVEKIHEDQILV--------------YNPSSMSRPMQEYIVKRVNLTKIFSEYGFELIDCVHFDTIIERS----- 787 Rabbit fibroma virus... P0DSX5 735 SENYMSVEKIADDRIVV--------------YNPSTMSTPMTEYIIKKNDIVRVFNEYGFVLVDNVDFATIIERS----- 795 Variola virus human/... Q9VJQ4 279 FGNDVYSIEFDCETDPLplfg------akyqFHLEGVV-DCPEFLVHFPTLVKLGRKYGLQLLKRSTFADYYKENlh--h 349 fruit fly Q9D0L8 325 FGNEIYTVKFQ-KKGNYplfg------ckydFNLEGVV-DVPEFLVYFPLLTEMAKKYNMKLIYKKTFLEFYEEKiknne 396 house mouse Q28FT4 265 FGNDVYTVKFE-KKGKYplfg------ckydFSLEEVV-NVPEFLVYFPVLVEMAKKYQMKLIYKKTFREFFEEKvknde 336 tropical clawed frog
Q98257 901 -RAFIDGVAqmesrts-----------------tknffeLNRAALQSCRGLDVEELLQ-YYVVYVFAKR 950 Molluscum contagiosum virus sub... O74880 321 yGPLMDRMK------------------------------VVDNEGHRGIGGQEKEAAG-FYLAFAFEKR 358 Schizosaccharomyces pombe 972h- P32783 384 iERFSPKMRe----------------------------gLQRSDGRYGVEGDEKEAASyFYTMFAFRKV 424 Saccharomyces cerevisiae S288C Q5ADX5 435 fSKLNKNLId----------------------------gMKRSDGKYGAEGDEKEAVA-FYIGFVFEKV 474 Candida albicans SC5314 Q9LHQ7 302 fVELMRRLGa----------------------------lGDGSNDQSTLSADEWEAAY-LYLSFVLRKR 341 thale cress P25950 788 -KRFINSVSkmeerks-----------------tknffeLNREALK-HEGTDIDDLLR-YYIVYVFSKR 836 Rabbit fibroma virus (strain Ka... P0DSX5 796 -KKFINGAStmedrps-----------------trnffeLNRGAIK-CEGLDVEDLLS-YYVVYVFSKR 844 Variola virus human/India/Ind3/... Q9VJQ4 350 gRHLLQRMSglesvqpqrcen------deefahvsnfqgAQRSRSVGTLSKSEWEAAT-LYLVCAFKKC 411 fruit fly Q9D0L8 397 nKMLLKRMQaleqypahensklasekvgdythaaeylkkSQVRLPLGTLSKSEWEATS-IYLVFAFEKQ 464 house mouse Q28FT4 337 qKMLLKRMKalepypaapnfklvsgrtedyehaqklvenGQVKLPLGTLSKSEWEATS-IYLLFAFEKQ 404 tropical clawed frog
Jiyao W et al.(2023). "The conserved domain database in 2023.",