3B8E,3IXZ,3WGU,4XE5,2ZXE


Conserved Protein Domain Family
P-type_ATPase_Na-K_like
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cd02608: P-type_ATPase_Na-K_like 
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alpha-subunit of Na(+)/K(+)-ATPases and of gastric H(+)/K(+)-ATPase, similar to the human Na(+)/K(+)-ATPase alpha subunits 1-4
This subfamily includes the alpha subunit of Na(+)/K(+)-ATPase a heteromeric transmembrane protein composed of an alpha- and beta-subunit and an optional third subunit belonging to the FXYD proteins which are more tissue specific regulatory subunits of the enzyme. The alpha-subunit is the catalytic subunit responsible for transport activities of the enzyme. This subfamily includes all four isotopes of the human alpha subunit: (alpha1-alpha4, encoded by the ATP1A1- ATP1A4 genes). Na(+)/K(+)-ATPase functions chiefly as an ion pump, hydrolyzing one molecule of ATP to pump three Na(+) out of the cell in exchange for two K(+)entering the cell per pump cycle. In addition Na(+)/K(+)-ATPase acts as a signal transducer. This subfamily also includes Oreochromis mossambicus (tilapia) Na(+)/K(+)-ATPase alpha 1 and alpha 3 subunits, and gastric H(+)/K(+)-ATPase which exchanges hydronium ion with potassium and is responsible for gastric acid secretion. Gastric H(+)/K(+)-ATPase is an alpha,beta-heterodimeric enzyme. This subfamily belongs to the P-type ATPases, a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.
Links
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Statistics
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PSSM-Id: 319794
Aligned: 28 rows
Threshold Bit Score: 1650.54
Created: 28-Apr-2005
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
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  next features
Conserved site includes 7 residues -Click on image for an interactive view with Cn3D
Feature 1: P-type ATPase signature motif, 7 residue positions
Conserved feature residue pattern:D K [TS] G T [LIVM] [TS]Click to see conserved feature residue pattern help
Evidence:
  • Comment:a characteristic P-type ATPase conserved sequence motif: DK[TS]GT[LIVM][TS], in which D is the reversibly phosphorylated Asp
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1                                                                                         
3B8E_A         37 GLTPARAAEILARDGPNaltpppttpewvkfcrqlFGGFSMLLWIGAILCFLaygiqaat-eeepqndNLYLGVVLSAVV 115  pig
3IXZ_A         72 GLSASLAAELLLRDGPNalrpprgtpeyvkfarqlAGGLQCLMWVAAAICLIafaiqase-gdlttddNLYLALALIAVV 150  pig
3WGU_A         55 GLTPARAAEILARDGPNaltpppttpewvkfcrqlFGGFSMLLWIGAILCFLaygiqaat-eeepqndNLYLGVVLSAVV 133  pig
Q92126         69 GLKSAFAAEVILRDGPNelkppkgtpeyikfarqlAGGLQCLMWVAAVICLIafgieesq-gdltsadNLYLAITLIAVV 147  African clawe...
Q6RWA9         53 GLTSEQAKTRLDRDGPNaltppkttpewvkfcknmFGGFSLLLWIGAVLCFIahgipcwcagepylydNLYLGIVLAAVV 132  pork tapeworm
ABO61332       67 GLSPEKAKEILLRDGPNcltppkttpewvkfcktlFGGFSMLLWIGAILCFIaygiqagt-yddppgdNLYLGIVLTAVV 145  longfin insho...
NP_732572      80 GLSHAKAKENLERDGPNaltppkqtpewvkfcknlFGGFAMLLWIGAILCFVaysiqast-seepaddNLYLGIVLSAVV 158  fruit fly
NP_506269      40 GLTRQKAQEVLAKNGPNalsppettpewikfcknlFGGFAMLLWVGAILCYIaysvdyft-meypskdNLYLGIVLMTVV 118  Caenorhabditi...
NP_001104092   51 GLSFVEAKLRLEINGPNiltpqpptpkwivflktmFGGFAILLWAGSFLCFVgyliqlqt-qheppddNLYLGIALTVLV 129  fruit fly
P28774         42 GLTNAQARSNIERDGPNcltppkttpewikfcknlFGGFALLLWTGAILCFLaygieassgnedmlkdNLYLGIVLATVV 121  Artemia franc...

Feature 1                                                                                         
3B8E_A        116 IITGCFSYYQEaksskimesfknMVPQQALVIRngekMSINAEEVVVGDLVEVkgGDRIPADLRIIsangCKVDNSsLTG 195  pig
3IXZ_A        151 VVTGCFGYYQEfkstniiasfknLVPQQATVIRdgdkFQINADQLVVGDLVEMkgGDRVPADIRILqaqgRKVDNSsLTG 230  pig
3WGU_A        134 IITGCFSYYQEaksskimesfknMVPQQALVIRngekMSINAEEVVVGDLVEVkgGDRIPADLRIIsangCKVDNSsLTG 213  pig
Q92126        148 VVTGCFGYYQEfkstniiasfknLVPQQATVVRdgdkFQINANQLVVGDLVEIkgGDRVPADIRIItsqgCKVDNSsLTG 227  African clawe...
Q6RWA9        133 VITGCFSYYQEsksskimesfakLVPQYAVVIRggqrIDAPAEALVVGDIIDVkfGDRVPADIRVIkassFKVDNSaLTG 212  pork tapeworm
ABO61332      146 IVTGIFSYYQEaksskimdsfknMVPQYAVVVRsgekLNVRAEELVVGDMVEVkfGDRIPADIRVVaahsFKVDNSsLTG 225  longfin insho...
NP_732572     159 IVTGIFSYYQEsksskimesfknMVPQFATVIRegekLTLRAEDLVLGDVVEVkfGDRIPADIRIIearnFKVDNSsLTG 238  fruit fly
NP_506269     119 VITGVFQYYQEsksskimdsfknMVPTFALVHRdgqkQQVKTEELVVGDIVEVkgGDRVPADLRVVsafgFKVDNSsLTG 198  Caenorhabditi...
NP_001104092  130 IVTGLFTYFQVhksssimdsfknLVPQYATVIRegeiNTVTSDEIVKGDIVEVkfGDRVPADIRILeahgLKVDNSsLTG 209  fruit fly
P28774        122 IVTGIFSYYQEnkssrimdsfknLVPQYALALRegqrVTLKAEELTMGDIVEVkfGDRVPADLRVLearsFKVDNSsLTG 201  Artemia franc...

Feature 1                                                                                         
3B8E_A        196 ESePQTRspdftnenplETRNIAFfSTNCveGTARGIVVYTGdrTVMGRIATLASGLeggqTPIAAEIEHFIHIITGVAV 275  pig
3IXZ_A        231 ESePQTRspecthesplETRNIAFfSTMCleGTAQGLVVNTGdrTIIGRIASLASGVenekTPIAIEIEHFVDIIAGLAI 310  pig
3WGU_A        214 ESePQTRspdftnenplETRNIAFfSTNCveGTARGIVVYTGdrTVMGRIATLASGLeggqTPIAAEIEHFIHIITGVAV 293  pig
Q92126        228 ESePQTRspeythesplETRNIAFfSTMCleGTATGIIINTGdrTIIGRIATLASGVgnekTPIAIEIEHFVDIIAGLAI 307  African clawe...
Q6RWA9        213 ESePQTRtaeytnenplETKNLAFfSTNAveGTCRGVVVATGdrTVMGRIANLASGLemgaTPIAREIAHFIHIITGVAV 292  pork tapeworm
ABO61332      226 ESePQSRsaeftnenplETKNLAFfSTNAveGTCVGLVVKTGdkTVMGRIANLASGLevgeTPIAKEIAHFIHLITGVAV 305  longfin insho...
NP_732572     239 ESePQSRgaefthenplETKNLAFfSTNAveGTAKGVVISCGdhTVMGRIAGLASGLdtgeTPIAKEIHHFIHLITGVAV 318  fruit fly
NP_506269     199 ESePQSRspdctnenplETRNIAFfSTNAveGTAKGIVIYTGdnTVMGRIAHLASGLdtgmTPIAREIEHFIHLITGVAV 278  Caenorhabditi...
NP_001104092  210 ESePQVRstefthenplETKNLAFfSTNVleGTCRGVVIATGdsTVMGRIANLAAGLddvqSPISREIQLFIRFITIFAI 289  fruit fly
P28774        202 ESePQARspeftndnplETKNLAFfSTNAveGTMRGIVIGIGdnTVMGRIAGLASGLdtgeTPIAKEIAHFIHIITGVAV 281  Artemia franc...

Feature 1                                                                                    #####
3B8E_A        276 FLGVSFFIlslileytwleavIFLIGIIVANVPEGLLATVTVCLTLTAKRMarkncLVKNLEAVETLGSTsTICSDKTGT 355  pig
3IXZ_A        311 LFGATFFIvamcigytflramVFFMAIVVAYVPEGLLATVTVCLSLTAKRLaskncVVKNLEAVETLGSTsVICSDKTGT 390  pig
3WGU_A        294 FLGVSFFIlslileytwleavIFLIGIIVANVPEGLLATVTVCLTLTAKRMarkncLVKNLEAVETLGSTsTICSDKTGT 373  pig
Q92126        308 FFGATFFVvamvigytflramVFFMAIVVAYVPEGLLATVTVCLSLTAKRLarkncVVKNLEAVETLGSTsVICSDKTGT 387  African clawe...
Q6RWA9        293 FLGVTFFIiafilgyywldavIFLIGIIVANVPEGLLATVTVCLTLTAKRMaskncLVKNLEAVETLGSTsTICSDKTGT 372  pork tapeworm
ABO61332      306 FLGVTFFViafilgyywldavIFLIGIIVANVPEGLLATVTVCLTLTAKRMarkncLVKNLEAVETLGSTsTICSDKTGT 385  longfin insho...
NP_732572     319 FLGVTFFViafilgyhwldavIFLIGIIVANVPEGLLATVTVCLTLTAKRMaskncLVKNLEAVETLGSTsTICSDKTGT 398  fruit fly
NP_506269     279 FLGISFFIiafilgyhwltavVFLIGIIVANVPEGLIATVTVCLTLTAKRMaskncLVKNLEAVETLGSTsTICSDKTGT 358  Caenorhabditi...
NP_001104092  290 ILGLSFFAisltlgyefidavVFLIGIIVANVPEGLLVTVTVCLTLTAKRMaskncLVKNLEAVETLGSTsTICSDKTGT 369  fruit fly
P28774        282 FLGVTFFIiafvlgyhwldavVFLIGIIVANVPEGLLATVTVCLTLTAKRMaskncLVKNLEAVETLGSTsTICSDKTGT 361  Artemia franc...

Feature 1         ##                                                                              
3B8E_A        356 LTQNrMTVAHMWSdnqiheadttenqsgvsfdktsatwlalsriagLCNRAvfqanqenlpilkravaGDASESALLKci 435  pig
3IXZ_A        391 LTQNrMTVSHLWFdnhihsadttedqsgqtfdqssetwralcrvltLCNRAafksgqdavpvpkriviGDASETALLKfs 470  pig
3WGU_A        374 LTQNrMTVAHMWFdnqiheadttenqsgvsfdktsatwlalsriagLCNRAvfqanqenlpilkravaGDASESALLKci 453  pig
Q92126        388 LTQNrMTVSHLWFdnhihsadttedqsgqsfdqtsdtwralskvvsLCNRAffksgqdgipvpkriviGDASETALVKfs 467  African clawe...
Q6RWA9        373 LTQNrMTVAHMWFdnkifeadtsddqstanysrasstwmalsriamLCNRAefkpgeetnpvlkrecnGDASESALLKcv 452  pork tapeworm
ABO61332      386 LTQNrMTVAHMWYggkiveadtsedqsnatynkdtadwialsriamLCNRAefkagqdnvpvlkkecnGDASESALLKcv 465  longfin insho...
NP_732572     399 LTQNrMTVAHMWFdnqiieadttedqsgvqydrtspgfkalsriatLCNRAefkggqdgvpilkkevsGDASEAALLKcm 478  fruit fly
NP_506269     359 LTQNrMTVAHMWYdetihecdttetqtsq-ekrtgasfealvriasLCNRAefkagqqdtpilrrdctGDASEIALLKft 437  Caenorhabditi...
NP_001104092  370 LTQNrMTVAHLWYdqiivesdttesfrgshfkiedksfnalfmcaaLCNSAefkggqddipvfkkdvnGNASEAALLKft 449  fruit fly
P28774        362 LTQNrMTVAHMWFdgtiteadttedqsgaqfdkssagwkalvkiaaLCSRAefkpnqsttpilkrevtGDASEAAILKcv 441  Artemia franc...

Feature 1                                                                                         
3B8E_A        436 elccgsvkemrerytKIVEIPFNSTNKYQLSIHKnpntaeprHLLVMKGAPERIldrcssilihgkeqpldeelkdAFQN 515  pig
3IXZ_A        471 eltlgnamgyrerfpKVCEIPFNSTNKFQLSIHTledprdprHVLVMKGAPERVlercssilikgqelpldeqwreAFQT 550  pig
3WGU_A        454 elccgsvkemrerytKIVEIPFNSTNKYQLSIHKnpntaeprHLLVMKGAPERIldrcssilihgkeqpldeelkdAFQN 533  pig
Q92126        468 eitvgnvmeyrerfkKVTEVPFNSTNKFQLSIHElqdpldlrYLMVMKGAPERIlercstimikgqelpldeqwkeAFQT 547  African clawe...
Q6RWA9        453 glsiggvtgyrtdkpKVAEIPFNSTNKYQVSVHQtddg-derYLVVMKGAPERIldrcstvlmegqelhmddqwreSFNN 531  pork tapeworm
ABO61332      466 elsignvpeyrrrnkKVVEIPFNSTNKYQVSIHEnedpndprYILVMKGAPERImdrcstalmngkdldvdetfrtNFNA 545  longfin insho...
NP_732572     479 elalgdvmnirkrnkKIAEVPFNSTNKYQVSIHEtedtndprYLLVMKGAPERIlercstifingkekvldeemkeAFNN 558  fruit fly
NP_506269     438 eltqgnviavreknkKIAEIPFNSTNKYQVSIHDng----dhYLLVMKGAPERIldvcstiflngkeseltdklreDFNT 513  Caenorhabditi...
NP_001104092  450 etifagigafrqkhiKLTEIPFNSTEKYQVSVHEfnss-dgyFIVEMKGAPERIldrcstiiiqglsveltptlklEFEE 528  fruit fly
P28774        442 elttgeteairkrnkKICEIPFNSANKFQVSIHEnedksdgrYLLVMKGAPERIlercstifmngkeidmteelkeAFNN 521  Artemia franc...

Feature 1                                                                                         
3B8E_A        516 AYLELGglGERVLGFChlflpdeqfpegfqfdtddvnfpldnlCFVGLISMIDPPRaaVPDAVGKCRsAGIKVIMVTGDH 595  pig
3IXZ_A        551 AYLSLGglGERVLGFCqlylsekdyppgyafdveamnfptsglSFAGLVSMIDPPRatVPDAVLKCRtAGIRVIMVTGDH 630  pig
3WGU_A        534 AYLELGglGERVLGFChlflpdeqfpegfqfdtddvnfpldnlCFVGLISMIDPPRaaVPDAVGKCRsAGIKVIMVTGDH 613  pig
Q92126        548 AYMDLGglGERVLGFChlylnekeysrgfnfdteemnfptsglCFAGLISMIDPPRatVPDAVMKCRtAGIRVIMVTGDH 627  African clawe...
Q6RWA9        532 AYLELGgiGERVLGFCdlrlpadkfprgfkfdidepnfpiegmPFVGLMSMIDPPRaaVPDAVSKCRsAGIKVVMVTGDH 611  pork tapeworm
ABO61332      546 AYMELGglGERVLGFCdyilptesfppgfqfdgdevnfpltglRFVGLMSMIDPPRaaVPDAVGKCRsAGIKVIMVTGDH 625  longfin insho...
NP_732572     559 AYMELGglGERVLGFCdfmlpsdkypngfkfntddinfpidnlRFVGLMSMIDPPRaaVPDAVAKCRsAGIKVIMVTGDH 638  fruit fly
NP_506269     514 AYLELGgmGERVLGFCdfvlpadkfpkgfkfdveevnfplknlRFVGLMSMIDPPRaaVPDAVAKCRsAGIKVVMVTGDH 593  Caenorhabditi...
NP_001104092  529 AYLEMGgmGERVLGFAdlllpmskypisyefsadppnfplenlRFLGLISLIDPPRaaVPDAVAKCRsAGVRVIMVTGDH 608  fruit fly
P28774        522 AYMELGglGERVLGFCdyllpldkyphgfafnaddanfpltglRFAGLMSMIDPPRaaVPDAVAKCRsAGIKVIMVTGDH 601  Artemia franc...

Feature 1                                                                                         
3B8E_A        596 pITAKAIAKGVGIisegnetvediaarlnipvsqvnprdakacvvhgsdlkdmtseqlddilkyhteIVFARTSPQQKLI 675  pig
3IXZ_A        631 pITAKAIAASVGIisegsetvediaarlrvpvdqvnrkdaracvingmqlkdmdpselvealrthpeMVFARTSPQQKLV 710  pig
3WGU_A        614 pITAKAIAKGVGIisegnetvediaarlnipvsqvnprdakacvvhgsdlkdmtseqlddilkyhteIVFARTSPQQKLI 693  pig
Q92126        628 pITAKAIAASVGIisegsetvediaarlripveqvnkrdaracvinggqlkemsseelvealklhpeMVFARTSPQQKLI 707  African clawe...
Q6RWA9        612 pITAKAIAKGVGIisdgnktvediaaergvpvsqvnpreasacvvhgsdlrdmtpaqideilenhseIVFARTSPQQKLI 691  pork tapeworm
ABO61332      626 pITAKAIAKGVGIisegsktvedisaeqgipvdqvnsgdagaavihgtdlrdmtpaqiddilrnhseIVFARTSPQQKLI 705  longfin insho...
NP_732572     639 pITAKAIAKSVGIisegnetvediaqrlnipvsevnpreakaavvhgaelrdvssdqldeilryhteIVFARTSPQQKLI 718  fruit fly
NP_506269     594 pITAKAIAKSVGIisdgtetvediairrgipveevnpreakaavihgsdlremsedqlaeiikyhseIVFARTSPQQKLM 673  Caenorhabditi...
NP_001104092  609 pITAKAIARSVGIittptaediakqrgvtvldidsrqat--aivvhggelremkaeeldaviyyhneIVFARTSPQQKLI 686  fruit fly
P28774        602 pITAKAIAKSVGIisegnetvediaarlnipvsevnprdakaavvhggelrditpdaldeilrhhpeIVFARTSPQQKLI 681  Artemia franc...

Feature 1                                                                                         
3B8E_A        676 IVEGCQrqgaiVAVTGDGVNDSPASKKADIGVAMGiaGSDVSKQAADMILLDDNFASIVtGVEEGRLIFDNLKKSIAYTL 755  pig
3IXZ_A        711 IVESCQrlgaiVAVTGDGVNDSPALKKADIGVAMGiaGSDAAKNAADMILLDDNFASIVtGVEQGRLIFDNLKKSIAYTL 790  pig
3WGU_A        694 IVEGCQrqgaiVAVTGDGVNDSPALKKADIGVAMGiaGSDVSKQAADMILLDDNFASIVtGVEEGRLIFDNLKKSIAYTL 773  pig
Q92126        708 IVESCQklgaiVAVTGDGVNDSPALKKADIGVAMGiaGSDAAKNAADMILLDDNFASIVtGVEQGRLIFDNLKKSIAYTL 787  African clawe...
Q6RWA9        692 IVEGIQrmgaiVAVTGDGVNDSPALKKADIGVAMGitGSDVSKQAADMILLDDNFASIVtGVEEGRIIFDNLKKSIAYTL 771  pork tapeworm
ABO61332      706 IVEGCQrqghiVAVTGDGVNDSPALKKADIGVAMGiaGSDVSKQAADMILLDDNFASIVtGVEEGRLIFDNLKKSIAYTL 785  longfin insho...
NP_732572     719 IVEGCQrmgaiVAVTGDGVNDSPALKKADIGVAMGiaGSDVSKQAADMILLDDNFASIVtGVEEGRLIFDNLKKSIAYTL 798  fruit fly
NP_506269     674 IVEGFQkqgqiVAVTGDGVNDSPALKKADIGVAMGiaGSDVSKQAADMILLDDNFASIVvGVEEGRLIFDNLKKSIAYTL 753  Caenorhabditi...
NP_001104092  687 IVEACQrrgeiVAVTGDGVNDSPALKRADIGVAMGisGSDVSKQAADMILLDDNFASIVvGIEEGRIIFDNLKKSIAYTL 766  fruit fly
P28774        682 IVEGCQrqgaiVAVTGDGVNDSPALKKADIGVAMGiaGSDVSKQAADMILLDDNFASIVtGVEEGRLIFDNLKKSIVYTL 761  Artemia franc...

Feature 1                                                                                         
3B8E_A        756 TSNIPEITPFLIFIIAniPLPLGTVTILCIDLGTDMVPAISLAyeqAESDIMKRQPRnpktdklvneqlismAYGQIGMI 835  pig
3IXZ_A        791 TKNIPELTPYLIYITVsvPLPLGCITILFIELCTDIFPSVSLAyekAESDIMHLRPRnpkrdrlvneplaaySYFQIGAI 870  pig
3WGU_A        774 TSNIPEITPFLIFIIAniPLPLGTVTILCIDLGTDMVPAISLAyeqAESDIMKRQPRnpktdklvnerlismAYGQIGMI 853  pig
Q92126        788 TKNIPELAPYLIYITAsvPLPLGCITILFIELCTDIFPSVSLAyerAESDIMHLKPRnprrdrlvnealavySYFQIGII 867  African clawe...
Q6RWA9        772 TSNIPEITPFLIFILAdvPLPLGTITILCIDLGTDMVPAISLAy-eEAEDIMKRMPRdpfrdklvnerlismAYGQIGMI 850  pork tapeworm
ABO61332      786 TSNIPEISPFLFFILLdiPLPLGTITILCIDLGTDMVPAISLAyeqAESDIMKRQPRdpvndklvnerlismAYGQIGMI 865  longfin insho...
NP_732572     799 TSNIPEISPFLAFILCdiPLPLGTVTILCIDLGTDMVPAISLAyehAEADIMKRPPRdpfndklvnsrlismAYGQIGMI 878  fruit fly
NP_506269     754 TSNIPEISPFLTYILFgiPLPLGTVTILCIDLGTDMVPAISLAyeeAESDIMKRQPRdpirdklvnerlislAYGQIGMI 833  Caenorhabditi...
NP_001104092  767 TSNLPEIVPFLFFVIFdiPLALGTIAILCIDIGTDMLPAISLAyekAESDIMARMPRdpfedrlvnkklilmAYLQIGVI 846  fruit fly
P28774        762 TSNIPEISPFLLFILFdiPLPLGTVTILCIDLGTDMVPAISLAyeeAESDIMKRRPRnpvtdklvnerlislAYGQIGMI 841  Artemia franc...

Feature 1                                                                                         
3B8E_A        836 QALGGFFTYFVILAENGFLPIHLLGLRVNWDDRWINDVEDSYGQQWTYEQRKIVEFTCHTPFFVTIVVVQWADLVICKTR 915  pig
3IXZ_A        871 QSFAGFTDYFTAMAQEGWFPLLCVGLRPQWENHHLQDLQDSYGQEWTFGQRLYQQYTCYTVFFISIEMCQIADVLIRKTR 950  pig
3WGU_A        854 QALGGFFTYFVILAENGFLPIHLLGLRVNWDDRWINDVEDSYGQQWTYEQRKIVEFTCHTAFFVSIVVVQWADLVICKTR 933  pig
Q92126        868 QSFAGFVDYFTVMAQEGWFPAYVLGLRSHWENQHLQDLQDSYGQEWTFSQRLYQQYTCYTVFFISYEICQISDVLIRKTR 947  African clawe...
Q6RWA9        851 QASGGFFVYFVIMAENGFWPSRLLGLRKQWDSPAINDVADSYGQEWTYTQRKRLEYTCHTAFFASIVIVQWTDLLICKTR 930  pork tapeworm
ABO61332      866 QASAGFFTYFVIMAENGFWISQLLGIRKNWDSMGVNDLEDSYGQEWTYAQRKKLEYTCHTAFFVSIVVVQWADLIICKTR 945  longfin insho...
NP_732572     879 QAAAGFFVYFVIMAENGFLPKKLFGIRKMWDSKAVNDLTDSYGQEWTYRDRKTLEYTCHTAFFISIVVVQWADLIICKTR 958  fruit fly
NP_506269     834 QASAGFFTYFWIMADNGFMPWDLYQLRAQWDSRAYNNVLDSYGQEWTYANRKILEYTCQTAYFVSIVVVQWADLIISKTR 913  Caenorhabditi...
NP_001104092  847 QTVACFFTFFAIMAEHGFPPSRLKGIREDWDSKNVEDLEDGYGQEWTYRERKVLEYTAGTGFFVSIVVTQVFDLLICKTR 926  fruit fly
P28774        842 QASAGFFVYFVIMAECGFLPWDLFGLRKHWDSRAVNDLTDSYGQEWTYDARKQLESSCHTAYFVSIVIVQWADLIISKTR 921  Artemia franc...

Feature 1                                                                                         
3B8E_A        916 RNSVFQQGM-KNKILIFGLFEETALAAflsycpgmgvalrmypLKPTWWFCAFPYslLIFVYDEVRKLIIRRRPGGWVEK 994  pig
3IXZ_A        951 RLSAFQQGFfRNRILVIAIVFQVCIGCflcycpgmpnifnfmpIRFQWWLVPMPFglLIFVYDEIRKLGVRCCPGSWWDQ 1030 pig
3WGU_A        934 RNSVFQQGM-KNKILIFGLFEETALAAflsycpgmgvalrmypLKPTWWFCAFPYslLIFVYDEVRKLIIRRRPGGWVEK 1012 pig
Q92126        948 RLSVFQQGFfRNKVLVIAIVFQLCLGNflcycpgmpnvfnfmpIRFQWWLVPLPFgiLIFVYDEIRKLGVRRHPGSWFDK 1027 African clawe...
Q6RWA9        931 KNSIYQQGM-WNHHLTFGLFFETTLAIflsycpglehglrmmpLRWTWWLPVLPFsvSIFIFDEVRKKFLRTLPPGNWVE 1009 pork tapeworm
ABO61332      946 RLSLFQQGM-KNHRLTFGIIFETILAAfltycpgldqglrmqpLRASWWFPAFPYslLIFIYDECRKLILRRHPGGWVEN 1024 longfin insho...
NP_732572     959 RNSIFQQGM-RNWALNFGLVFETVLAAflsycpgmekglrmypLKLVWWFPAIPFalAIFIYDETRRFYLRRNPGGWLEQ 1037 fruit fly
NP_506269     914 RNSLVQQGM-SNWTLNFGLVFETALAWfmcycpgldnglrmygLRFSWWFCALPFsiLIFVYDEIRRFLIRRYPGGWVER 992  Caenorhabditi...
NP_001104092  927 RNSILQQGM-GNHVLNFALVLEFIIACllcyvpvfektlrmysIKFIWWIYAFPFglLIFFFDESRRFLIRRNPGGWVEQ 1005 fruit fly
P28774        922 RNSVFQQGM-RNNILNFALVFETCLAAflsytpgmdkglrmypLKINWWFPALPFsfLIFVYDEARKFILRRNPGGWVEQ 1000 Artemia franc...

Feature 1          
3B8E_A        995 E 995  pig
3IXZ_A       1031 E 1031 pig
3WGU_A       1013 E 1013 pig
Q92126       1028 E 1028 African clawed frog
Q6RWA9       1010 R 1010 pork tapeworm
ABO61332     1025 E 1025 longfin inshore squid
NP_732572    1038 E 1038 fruit fly
NP_506269     993 E 993  Caenorhabditis elegans
NP_001104092 1006 E 1006 fruit fly
P28774       1001 E 1001 Artemia franciscana

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