6KSP,6LU9,7EU7,5UN1,7LZH


Conserved Protein Domain Family
Lig_chan

?
pfam00060: Lig_chan 
Ligand-gated ion channel
This family includes the four transmembrane regions of the ionotropic glutamate receptors and NMDA receptors.
Statistics
?
PSSM-Id: 459656
Aligned: 48 rows
Threshold Bit Score: 180.967
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
?
Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
6KSP_A 542 DFAVWACIAAAIPVVGVLIFVLNRIQAVRSQSAtqprpsASATLHSAIWIVYGAFVQQgGESSVNSVAMRIVMGSWWLFT 621 
O81078 566 SLELWVTTGCFFVFIGFVVWLFEHRVNTDFRGP------PQYQIGTSLWFSFSTMVFA-HRENVVSNLARFVVVVWCFVV 638  thale cress
O04660 574 TLALWLISLLSFFIIGLVVWVLEHRVNPDFDGP------GQYQLSTIFWFSFSIMVFA-PRERVLSFWARVVVIIWYFLV 646  thale cress
Q9SHV1 580 SIELWLTTLVFFFLVGISVWTLEHRVNSDFRGP------ANYQASTIFWFAFSTMVFA-PRERVLSFGARSLVVTWYFVL 652  thale cress
Q9SDQ4 578 TSRLWCVVLVSFLVIAVVIWILEHRINEDFRGP------PRRQLSTMLLFSFSTLFKR-NQEDTISNLARLVMIVWLFLL 650  thale cress
Q7XJL2 591 TLPMWAVTASFFVIVGAAIWILEHRINDEFRGP------PRRQIITILWFTFSTMFFS-HRETTVSTLGRMVLLIWLFVV 663  thale cress
Q8GXJ4 613 TIEMWAVTGGFFLFVGAMVWILEHRFNQEFRGP------PRRQLITIFWFSFSTMFFS-HRENTVSSLGRFVLIIWLFVV 685  thale cress
Q8LGN0 582 SLDLWVTTACFFVFIGFIVWILEHRVNTDFRGP------PHHQIGTSFWFAFSTMNFA-HREKVVSNLARFVVLVWCFVV 654  thale cress
Q9C5V5 577 GLDLWVTTACFFVLIGFVVWLFEHRVNTDFRGP------PHHQIGTSFWFSFSTMVFA-HREKVVSNLARFVVVVWCFVV 649  thale cress
Q8LGN1 568 TLSLWLTIASFFILTGAIVWLIERHDNADFQGS------CFQQIGTLLCFGFSTLVFA-HRERLQHNMSRFVVIVWIFAV 640  thale cress
6KSP_A 622 LIVCSSYTANLAAFLTVSRMDSPVRTFQDLS-KQLEMSYGTVRDSAVYEYFRAKGTNPLEQDSTFAELWRTISKNGgadn 700 
O81078 639 LVLTQSYTASLTSFLTVQSLQPTVTNVNDLIkNRDCVGYQGGAFVKDILLGLGFHEDQLKPFDSAKDADDLLSKGK---- 714  thale cress
O04660 647 LVLTQSYTASLASLLTTQHLHPTVTNINSLLaKGESVGYQSSFILGRLRDSGFSEASLVSYGSPEHCDALLSKGQA---- 722  thale cress
Q9SHV1 653 LVLTQSYTASLASLLTSQQLNPTITSMSSLLhRGETVGYQRTSFILGKLNETGFPQSSLVPFDTAEECDELLKKGP---- 728  thale cress
Q9SDQ4 651 MVLTASYTANLTSILTVQQLPSAITGIDSLRaSEVPIGYQAGTFTLEYLTYSLGMARSRLVPLDSTEEYEKALKLG---- 726  thale cress
Q7XJL2 664 LIITSSYTASLTSILTVQQLNSPIKGVDTLI-SSTGRIGFQVGSFAENYMTDELNIASSRLVPLASPEEYANALQN---- 738  thale cress
Q8GXJ4 686 LIINSSYTASLTSILTIRQLTSRIEGIDSLVtSNEPIGVQDGTFARNYLINELNILPSRIVPLKDEEQYLSALQRG---- 761  thale cress
Q8LGN0 655 LVLIQSYTANLTSFFTVKLLQPTVTNWKDLIkFNKNIGYQRGTFVRELLKSQGFDESQLKPFGSAVECDELFSNGT---- 730  thale cress
Q9C5V5 650 LVLTQSYTANLTSFLTVQRFQPAAINVKDLIkNGDYVGYQHGAFVKDFLIKEGFNVSKLKPFGSSEECHALLSNGS---- 725  thale cress
Q8LGN1 641 LILTSNYTATLTSVMTVQQIRG-LKSNEN------IGFFSASIAANVVNDNPTFQGPRYKGLKTADDFTNALRNGT---- 709  thale cress
6KSP_A 701 cvsNPSEGIRKAKKGNYAFLwdVavveyAALTDDDCSVTVIGNSISSKGYGIALQHGSPYRDLFSQRILELQDTGDLDVL 780 
O81078 715 ---SKGIAAAFDEVAYLKAI----------LSQSCSKYVMVEPTFKTGGFGFAFPKNSPLTGEFSRAILNLTQNNVTQQI 781  thale cress
O04660 723 ---EGGVSAVLMEVPYVRIF---------LGQYCNKYKMVQTPFKVDGLGFVFPIGSPLVADISRAILKVEESNKANQLE 790  thale cress
Q9SHV1 729 ---KNGGVAAAFLGTPYVRL--F------LGQYCNTYKMVEEPFNVDGFGFVFPIGSPLVADVSRAILKVAESPKAVELE 797  thale cress
Q9SDQ4 727 ---PTNWGGVAAIVDELPYI--E------LFLAERTGFKIVGEPFMHRGWGFAFKRDSPLAIDMSTAILKLSETRKLQEI 795  thale cress
Q7XJL2 739 ---GTVAAIVDERPYIDL--------------FLSDYCKFAIRGQEFTRCGWGFAFPRDSPLAVDMSTAILGLSETGELQ 801  thale cress
Q8GXJ4 762 ---PNAGGVAAIVDELPYIE--Vl----LTNSNCKFRTVGQEFTRTGWGFAFQRDSPLAVDMSTAILQLSEEGELEKIHR 832  thale cress
Q8LGN0 731 ---ITASFDEVAYIKVIL-------------SQNSSKYTMVEPSFKTAGFGFVFPKKSPLTDDVSRAILNVTQGEEMQHI 794  thale cress
Q9C5V5 726 ---ISAAFDEVAYLRAIL-------------SQYCSKYAIVEPTFKTAGFGFAFPRNSPLTGDVSKAILNVTQGDEMQHI 789  thale cress
Q8LGN1 710 ---ISFIVDEVPYVKLFV-------------AKHPSEFVIVETESVTNGFGFAFQKGSPLVQKVSREIEKLRRTEKLKAI 773  thale cress
6KSP_A 781 KQKWWPHTg-RCDLTSHSSAQtdg---ksLKLHSFAGVFCILAIG 821 
O81078 782 EDRWFPKKn-DCPDPMTALSSn------rLNLSSFLGLFLIAGTA 819  thale cress
O04660 791 NAWFKPIDe-SCPDPLTNPDPnpsvsfrqLGFDSFWVLFLVAAIV 834  thale cress
Q9SHV1 798 HAWFKKKEq-SCPDPVTNPDSnptvtaiqLGVGSFWFLFLVVFVV 841  thale cress
Q9SDQ4 796 RKKWLCKT--NCAGKSNWNPEpn-----qLHLKSFKGLYLVC-IA 832  thale cress
Q7XJL2 802 KIHDRWLSksNCSSPHGSQSGds----eqLNVHSFWGMFLVVGIA 842  thale cress
Q8GXJ4 833 KWLNYKHE---CSMQISNSEDs------qLSLKSFWGLFLICGIT 868  thale cress
Q8LGN0 795 ENKWFKKPn-NCPDLNTSLSSn------hLSLSSFWGLFLIAGIA 832  thale cress
Q9C5V5 790 ENKWFMKQn-DCPDPKTALSSn------rLSLRSFWGLFLIAGIA 827  thale cress
Q8LGN1 774 ENWWFQRQ------TTSATSEdtf---hpLTVYTFRGLFMITGVS 809  thale cress
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap