Conserved Protein Domain Family
pyrB

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PRK13376: pyrB 
bifunctional aspartate carbamoyltransferase catalytic subunit/aspartate carbamoyltransferase regulatory subunit; Provisional
Statistics
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PSSM-Id: 237369
Aligned: 12 rows
Threshold Bit Score: 925.702
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
42525648    1 MENKFMGRSLTVIDDLSIDERKYLFDKTKRLKKAIQEDDQkvMDEFRINDKDFGIYEVFLEPSTRTKESFRNAAKFH--- 77 
302337948   2 NTNTFQGRTLAVIRDFSQEERLYLFSHTRRLKQALLEGDRktVDEYRIDDGDFGIYEVFLEDSTRTKESFKNAAQFH--- 78 
170289095   1 MKRDFLGRTLAVIEDLSVEEQMFLYEKTRELKQRWYSGED--VSDFRIKKRNVGIYIVFVEPSTRTKESFINAAKFHsgp 78 
15644390    1 MKRDFLGRTLAVIEDLSVEEQMFLYEKTRELKQRWYSGED--VSDFRIKKRNVGIYIVFVEPSTRTKESFINAAKFHsgp 78 
222099790   4 LKRDFLGRTLAVIEDLSVEEQMFLYEKTRELKKRWYSGED--VSDFRIRKRNVGIYIVFVEPSTRTKESFINAAKFHagp 81 
148270279   1 MKRDFLGRTLAVIEDLSVEEQMFLYEKTRELKQRWYNGED--VSDFRIKKRNVGIYIVFVEPSTRTKESFINAAKFHsgp 78 
281412585   1 MKRDFLGRTLAVIEDLSVEEQMFLYEKTRELKQRWYNGED--VSDFRIKKRNVGIYIVFVEPSTRTKESFINAAKFHsgp 78 
157363003   1 -MRSFRGRTLALIRDFTIDEQLFLYQKTKELKQKWLNRED--MSEFQIKG-DVNIYIVFVEPSTRTKESFINAAKFHk-- 74 
217077643   1 MKNDFLGRSLTVIEDFSVDEQMFLYAQTRKLKKLWKEKSD--ISEFQIKK-NVGIYIVFVEPSTRTKESFINAARFHk-- 75 
150021078   1 --MNFLGRSLTVINDFSVEEQLFLYEKTKILKSLWKEKKD--YSMFQIKK-DVGIYIIFVEPSTRTKESFINAAKFHk-- 73 
154248922   1 MKRDFLGRTLAVINDFSVEEQLFLYKSTQKLKEKIRNKED--VSEFQIKR-ETGIYIVFVEPSTRTKESFINAAKFHk-- 75 
160902441   1 MKNDFLGRSLTVMNDLTVEEQLFLYNQTKRLKAKWANKED--LTEFQIKN-QTGIYIVFLESSTRTKESFINASKFHk-- 75 
42525648   78 QVKLSDLAAESSSFNKGESYADTFNTLAGYQN-SIFIVRSKVEGVCRWLEDEAQAFYQRNNLKRkPAFINAGDGKHEHPT 156
302337948  79 GVKLNSLDVGHSSINKKESYADTFNTLCGYDN-KIFIVRSTLEGVCRWLEENGKEFARRNGLSVpPAFINAGDGKHEHPT 157
170289095  79 NVKVNVFDSEHSSFNKQESYTDTFSMLTGYSDySIFVVRTRLEGVCRLLERRISEFASRNGIEV-PSFINAGDGKHEHPT 157
15644390   79 NVKVNVFDSEHSSFNKQESYTDTFSMLTGYSDySIFVVRTRLEGVCRLLERRISEFASRNGIEV-PSFINAGDGKHEHPT 157
222099790  82 NVKVNIFDSEHSSFNKQESYTDTFAMLTGYSDySIFVVRTRLEGVCRLLERRISEFALRNGIEI-PSFINAGDGKHEHPT 160
148270279  79 NVKVNVFDSEHSSFNKQESYTDTFSMLTGYSDySIFVVRTRLEGVCRLLERRISEFASRNGIEV-PSFINAGDGKHEHPT 157
281412585  79 NVKVNVFDSEHSSFNKQESYTDTFSMLTGYSDySIFVVRTRLEGVCRLLERRISEFASRNGIEV-PSFINAGDGKHEHPT 157
157363003  75 NARVNIFDAEHSSFNKNESYVDTFNMLTGYGIySIFVVRTRLEGVPRLLERKVGEFAQRHGIER-PAFINGGDGKHEHPT 153
217077643  76 NAKVNIFDSEHSSFNKKESYLDTFNMLTGYSDySIFVLRTRLEGTCKYLDEKVSEFAERHGVEK-PAFINAGDGKHEHPT 154
150021078  74 NAKVNIFDSEHSSFNKKESYVDTFNMLTGYNDySIFIVRTRLEGTCKYLDEKVSDFAKRHGIEK-PAFINAGDGKHEHPT 152
154248922  76 NAKVNVFDSEHSSFNKQESYVDTFNMLTGYSGySIFILRTRLEGVTRLLEQKVGEFAERHGIER-PAFINGGDGKHEHPT 154
160902441  76 NAKINIFESEHSSFNKNESYIDTFNMLTGYSDySIFIIRSKLEGTCKLLDEKVSEFASRHNLPH-PSFINAGDGKHEHPT 154
42525648  157 QELLDEFTFIEDNNWSFDKIHIALVGDLYHGRTVHSKADGLKIFKSVKVDLIAPAELAMPEYYKVRMQENGFTVREFSSI 236
302337948 158 QELLDEFSFLEQLDWDESRLHIALVGDLYHGRTVHSKVDGLKLFGSVSVDLIAPKELAMPEYYVRKMEENDFAVRTFSSI 237
170289095 158 QELLDEYTFLEQNGFDNSFIHVALVGDLLHGRTVHSKVNGLKIFKNVKVDLVAPEELMMPEHYVEKMKKNGFEVRIFSSI 237
15644390  158 QELLDEYTFLEQNGFDNSFIHVALVGDLLHGRTVHSKVNGLKIFKNVKVDLVAPEELMMPEHYVEKMKKNGFEVRIFSSI 237
222099790 161 QELLDEYTFLEQNNFDNSYIHLALVGDLLHGRTVHSKVNGLKIFKNVKVDLVAPEELMMPEHYIERMKKNGFEVRTFSSI 240
148270279 158 QELLDEYTFLEQNGFDNSFIHVALVGDLLHGRTVHSKVNGLKIFKNVKVDLVAPEELMMPEHYVEKMKKNGFEVRIFSSI 237
281412585 158 QELLDEYTFLEQNGFDNSFIHVALVGDLLHGRTVHSKVNGLKIFKNVKVDLVAPEELMMPEHYVEKMKKNGFEVRIFSSI 237
157363003 154 QELLDEFTFLEQNNFDNSHIRIALIGDLLHGRTVHSKVDGLKIFKNVEVDLIAPQQIQMPQHYIEKMKSNGFEVRKFSSI 233
217077643 155 QELLDEYTFLEQMDFDNSFIHIALVGDLLHGRTVHSKVNGLKIFKNVLVDLIAPEEISMPPHYIKKMKENGFEVRIFDSI 234
150021078 153 QELLDEFTFLEQMNFDNSYIHIALVGDLLHGRTVHSKVNGLKIFKNVLVDLIAPEELAMPKHYVEKMKKNGYEVRIFDSI 232
154248922 155 QELLDEFTFLEQMNFDNSHIRIALVGDLLHGRTVHSKANGLKVFKNVEVDLIAPEELQMPKSYIEKMKRNGFEVRLYSSI 234
160902441 155 QEILDEFTFLEQMDFNNEYIHIALIGDLLHGRTVHSKVEGLKIFKNVEVDLIAPEELQMPKHYISKMKLKGYNVRIFSSI 234
42525648  237 EEYLRQAD-VALIWYFTRPQLERMGEQVLKKQDELRRSITFRKEFIEKLPENTRFYHPLPRHRVHPTIPTFLDATPLNGW 315
302337948 238 EEYLSQSN-TAPIWYFTRPQLERMGDDILKRQDELRSKIVFRREFLSKIADGTKFYHPLPRHKEHPTIPTFLDDTELNGW 316
170289095 238 REYLSQKD-VAKIWYFTRLQLERMGEDILEKVHILREAVTFKKEYLDALPEGVKFYHPLPRHKVYPTIPNFLDTLPLNGW 316
15644390  238 REYLDQKD-VAKIWYFTRLQLERMGEDILEKVHVLREAVTFKKEYLDALPEGVKFYHPLPRHKVYPTIPNFLDTLPLNGW 316
222099790 241 EEYLNQKD-VAKMWYFTRLQLERMGEDILEKVHLLREAVTFRKEFLEKLPEGVKFYHPLPRHKLYPTIPNFLDSLPLNGW 319
148270279 238 REYLSQKD-VAKIWYFTRLQLERMGEDILEKVHILREAVTFKKEYLDALPEGVKFYHPLPRHKVYPTIPNFLDTLPLNGW 316
281412585 238 REYLSQKD-VAKIWYFTRLQLERMGEDILEKVHILREAVTFKKEYLDALPEGVKFYHPLPRHKVYPTIPNFLDTLPLNGW 316
157363003 234 DEYLSNKD-VAKIWYFTRLQLERMGEDILEKEHILRKAVTFRKDMLDKVKEGTKFYHPLPRPKIDPEIPTFLDELPLNGW 312
217077643 235 ESYLKSTDkVAKIWYFTRLQLERMGEDILEKEHVLRKSVTFRKEFLEYIPQDVKFYHPLPRHKIYPTIPTFLDNLPLNGW 314
150021078 233 ENYLKEKN-IAPIWYFTRLQLERMGEDILEKEHLLRKSVTFRKDFLEKLPENVKFYHPLPRHKIYPTIPTFLDNLPLNGW 311
154248922 235 DEYLETTN-PAPIWYFTRLQLERMGEDILEKAHLLKKAVTFRKDMLDKIPEGTKFYHPLPRPKIDPEIPTFLDTLPLNGW 313
160902441 235 EEYLKQSK-KANIWYFTRLQLERMGEDILEKEHILRKSVTFTKEFLPLISENVKFYHPLPRHKTYPTIPTFLDPLPLNGW 313
42525648  316 ERQSINGMYVRMVLLSMIAGK--IGDDYKGPEPKsceRVEDEDYIVEVPINNskESKVETFSEGVRPIQNGIVIDHICRG 393
302337948 317 ENQSINGKLIRIVLLSLIAGK--IGHDFVPKAEKplaSVDDEPFLQDVPVAQ--DGPPKQYAEGVNPISDGIVIDHICRG 392
170289095 317 ETQARNGYWVRIVLLSMFGGA--LEAPFDTSKKE---EKPEEDFIIPAPITHgsKGVQKEGKRGIKPIENGTVIDHIAKG 391
15644390  317 ETQARNGYWVRIVLLSMFGGA--LEAPFDTSKKE---EKPEEDFIIPAPITHgsKGVQKEGKRGIKPIENGTVIDHIAKG 391
222099790 320 ETQARNGYWVRIVLLSMFGGA--IEAPFDTSKKA---PEKEEDFIIPAPIVHgtKGVQKDGKRGIKPIENGTVIDHIAKG 394
148270279 317 ETQARNGYWVRIVLLSMFGGA--LEAPFDTSKKE---EKPEEDFIIPAPITHgsKGVQKEGKRGIKPIENGTVIDHIAKG 391
281412585 317 ETQARNGYWVRIVLLSMFGGA--LEAPFDTSKKE---EKPEEDFIIPAPITHgsKGVQKEGKRGIKPIENGTVIDHIAKG 391
157363003 313 EIQARNGFWVRVVLLSLLGGAveMECDQSITFQK---EEDEYEFIIPTQIVHgtKGVAKEGKRGIKPIENGTVIDHIAKG 389
217077643 315 EQQAINGYWTRTVLLSMLGGA--LKANFDTSFNP---QENDEDFIIPAPIVNgtKGVSKEGKRGIKPIENGTVIDHIAKG 389
150021078 312 ETQAINGYWTRTVLLSMLGGA--LEAEFDTRTQP---EIPDEEFITPAPIVDgtKGILKEGKRGIKPIESGTVIDHIAKG 386
154248922 314 EHQAINGYWVRVVLLSMLGGA--LLADFDTTKKR---EELPDDFIIPAPIVDgtKGVAKEGKRGIKPISNGTVIDHIAKG 388
160902441 314 EKQAINGYWTRIILLSMLGGA--LTAPFDTSRKNl--EINEEDFIIPAPIKDgkKGLLSEGKRGIKPIENGTVIDHIAKG 389
42525648  394 DKPSVIRHHMSKIINVMGLEEgKGGEWVSTStkDKGTFKGIIFRPGEYkFSRADLKRLSAVASSCTLNLIKDGKIQSKYR 473
302337948 393 DSEQEIREHMARIIGVLKLYG-KGGEWVTSSriAPGTMKGIIFRPGFSgFDGKQMKQLAAIAPGSTLNIIHESRVVKKLR 471
170289095 392 KTPEEIYSTIVKIRKILRLYDvDSADGIFRS--SDGNFKGYISLPDRY-LSKREIKKLSAISPNTTVNIIKNSTVVEKYR 468
15644390  392 KTPEEIYSTILKIRKILRLYDvDSADGIFRS--SDGSFKGYISLPDRY-LSKKEIKKLSAISPNTTVNIIKNSTVVEKYR 468
222099790 395 KTPEEIYATIVKIRKILKLYDvDSADGIFRS--SDGSFKGYISLPDRY-LSKKEIKKLAAISPNTTVNIIKNSSVVEKYR 471
148270279 392 KTPEEIYSTIVKIRKILRLYDvDSADGIFRS--SDGNFKGYISLPDRY-LSKREIKKLSAISPNTTVNIIKNSTVVEKYR 468
281412585 392 KTPEEIYSTIVKIRKILRLYDvDSADGIFRS--SDGNFKGYISLPDRY-LSKREIKKLSAISPNTTVNIIKNSTVVEKYR 468
157363003 390 KSTEEIFNTIVKIRKILKLHDcDSADGIFKS--ADGSYKGYISLPDRY-LSKKEIKKLAAIAPNTTVNIIKGASVKEKYR 466
217077643 390 KDKDKIFETIVKIRKILKLFDlDSADGIFKS--ENGEFKGYISLPNRY-LSKKEIKMLSAISPNTTVNIIKNSRVVEKYR 466
150021078 387 KTKEQIFETIVKIRKILKLYDlDSADGIFKS--NDGNFKGYISLPDRY-LSKKEIKKLSAISPNTTVNIIKNSRVVEKYR 463
154248922 389 KTTEEIYNTIVKIRKILKIYDvDSADGIFKS--ADGNYKGYISLPDKY-LSFKEIKKLAAISPNTTVNIIKDSRVVEKYR 465
160902441 390 QKSEKIYETIMKIRKILKFYNiDSADGIFRS--ADGRLKGYISLPDVH-LSKKEIKKLSAISPNTTVNIIEGGRVKEKYR 466
42525648  474 THLPPRIYNFEDLICKNEACISHPAQSEGVPAIFYRTIDNRYACQYCGTIHTFKEIWG 531
302337948 472 LHMPPRIYNFDTISCSNTACISHPSNGESVPAEFFRVAGDIFVCKYCEKPHTFKEIWK 529
170289095 469 IKLPPTIYGFEELRCKNENCITNPAHGENASPSFVRNEKGQFICEYCETPHSFEEIWS 526
15644390  469 IKLPPTIYGFEELRCKNENCITNPAHGENASPSFVRNEKGQFICEYCETPHSFEEIWS 526
222099790 472 IKLPPTIYGFEELRCKNENCITNPAHGENVSPSFVRDENGRFVCEYCETPHSFEEIWS 529
148270279 469 IKLPPTIYGFEELRCKNENCITNPAHGENASPSFVRDEKGQFICEYCETPHSFEEIWS 526
281412585 469 IKLPPTIYGFEELRCKNENCITNPAHGENASPSFVRDEKGQFICEYCETPHSFEEIWS 526
157363003 467 IKLPPKIYNFDEIRCKNENCITHPKNGENVGASFIRID-DRLVCEYCETPHEYSEIWV 523
217077643 467 IFLPPFIYGFSELRCKNENCITNPVNGENAEAFFIRNNEGELVCKYCETPHSFEEIWN 524
150021078 464 ISLPPYIYGFAELKCKNENCITNPKHRENAEAFFVKNENGELVCKYCETPHTFEEIWN 521
154248922 466 LQLPPRIYNFDEIRCKNENCITNPAHGENVSASFIQVD-GKFVCEYCETPHEYHEIWN 522
160902441 467 ISLPPIIYGFEELRCKNENCITNPQNNENVQVSFIRNEENELICEYCETPHTFEEIWR 524
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