Conserved Protein Domain Family
polC

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PRK00448: polC 
DNA polymerase III PolC; Validated
Links
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Statistics
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PSSM-Id: 234767
Aligned: 185 rows
Threshold Bit Score: 1757.81
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
15674106    19 KNMENLFEKLMEQIKMPPNLrr------ssQFEHADIENVEVHT---ASKLWHFQLIFDEILPIDTYKLLTELTE----- 84  
71894029     3 EYKDVKVKSFANYFNLEFYE----------NLIDIKLLDYSIDQ---NTKKINLSFELDSFPTVNDFFAFIGNLD----- 64  
12044881     4 NLENEKDKKVLALSNFLIDNnildhnelnsLIERIESIYFNKYI---EEKVFLFAITISRPLTIDIWNALYEGFNelneg 80  
13357937     1 --METKNALFKKIVKISDQL-----------LNKISIKKLTKDK---KNNLFVYFDEFVDVTIIDELHQLSKTTL----- 59  
13507773    10 GKRIWALSQFLVKKNILDHNel------hqLNNRIELVYLENDR---ENALFLVALTLKKPLTIDIWNALYEGFQd---- 76  
148377333    3 SVGYKRFEAFCKANNIEINS----------ELQGTELVLFNQKYddnSNEKLKIEFRFKNPISYETIKKIKSFIR----- 67  
170762156    1 --METKNALFKKIVKISDQL-----------LNKISIKKLTKDK---KNNLFVYFDEFVDVTIIDELHQLSKTTL----- 59  
193216948    3 NEFDETFLKLCKEIKFELND----------EFRGTSFKEAKLNK---STHKWTFDIIFPHHISIDNFKDFKTHLD----- 64  
269115238    1 -MLDKTFVQLCKEIKFEFDEq---------QFYGAKVLSVESNL-----NEWKFKIAFANHIDIEQYKQFREKLV----- 60  
291320001    3 SVGYKRFEAFCKANNIEINS----------ELQGTELVLFNQKYdenSNEKLKIEFRFKNPISYETIKKLKSFIR----- 67  
15674106    85 -----TAFS---TIAR--TEISVSSRNQNIDEQNLNDYYQYALTL---------PELCDSAFSSIFKKY-HLEK-EEEKI 143 
71894029    65 ------------NIKDfkVFYSFSFLKINNTESWIEDFLKTACGYlklnelnsvNKVNNQFFYDEFSKSwKISL------ 126 
12044881    81 fkadnESFKltiTFKEnePFFKSKNSFSSVTIAIIKDYFHSFFSK---------DKKYKILIEQELSNP-NFLSyENDEL 150 
13357937    60 ---------------MhdLQIWYINNLKEVDHKKILTFFKKISEQnan---lifLEQINDLNTKIEYNS------NLNSL 115 
13507773    77 ----aEGAElriTFQEdaTFFKDGSTKSSVTLAIIKDYFKSFFGK---------DKKYRILLEQELTHP-NFLSySNHEL 142 
148377333   68 -------------LNKdrLDVSFVVSNDSYNKNSILQYVYQIIDK------------------TRFKTLnQINW-ENKFY 115 
170762156   60 ---------------MhdLQIWYINNLKEVDHKKILTFFKKISEQ----------NANLIFLEQINDLNtKIEYnSNLNS 114 
193216948   65 -----KRFPn--------NNFSFSVRSLIRDKSTIIDYLHYVFLC---------DHSPLLAYKNFFNMD-LVSL-EGDDF 120 
269115238   61 -----KRFGk--------VELILAIETIIRNKQIIVDYLNYLIECnpkk-ywpfVKYNYSCITTSAIEI------DEKTL 120 
291320001   68 -------------LNKdrLDVSFVVSNDSYNKNSILQYVYQIIDK-----------TRFKPLNQINWEN-KFYV-DEDHI 121 
15674106   144 H-LMVEDNPQ-----MDFFVEKYFPIL-EEKFKSFGFGEVRITPLVDQELtet---qaaAHAEKVAARLA---AQTAEQA 210 
71894029   127 --TKTANEIK---------VEKELLKL-NKFLEKIGIDIIYCFIDNKDSAnnsdesdieSSVLNFVQ------NFQEEFE 188 
12044881   151 K-AQCQTKEL-----TEWLVQKSKSFI--FWMNNAGFKNFNFIALYPIDK-----------------------NESKLKV 199 
13357937   116 I-LKINDKLI-----YDHFIANKLEILnILKVWSLPYSNFEIHFENLSSLl-------nEKHEQAVNEII---SHHIQQQ 179 
13507773   143 K-ANCQSQEL-----DQWLIEQRQAFI--KWMHQAGFTHFGFVSLFN-PP-----------------------AEKQLKV 190 
148377333  116 VdDNHTGHFEnidrdFENQYGILLSKL-LNKLKEYGFVLLNFSYDYIQSS------------PESYSKSEeaaKQNEKIK 182 
170762156  115 LiLKINDKLI-----YDHFIANKLEILnILKVWSLPYSNFEIHFENLSSL--------------LNEKHE---QAVNEII 172 
193216948  121 I-LILPNQET-----YDGLKKLENNLKeSLENIGFGFYKIKLKIIEEDTK-----------------KRR---AKKIEAV 174 
269115238  121 TlSLLTNEIYevfksNKDLFKEALASI------GFDFYNVVFNLGLNNKK-----------------------SVASKKL 171 
291320001  122 G-HFENIDRD-----FENQYGILLSKL-LNKLKEYGFALFNFSYDYIQSS------------PESYSKLEeaaKQNEKIK 182 
15674106   211 QISEIKKQRSEERESKNtreakpefvetalsdgiffgrkisgqspiTSMSFIAGEGFgvifeglvfeaahreftgkesgk 290 
71894029   189 TNSPSTFSKNKFRKKQS--------------------------------------------------------------- 205 
12044881   200 KAVTVSQYDKQFETKVF--------------------------------------------------------------- 216 
13357937   180 KHLEQQISQQQNFYNNQkan-----------------------fnyYKNPS----------------------------- 207 
13507773   191 KSMKVSKYDKQFETEVF--------------------------------------------------------------- 207 
148377333  183 QELLKKMIELDSSSdky--------------------------dsyNSNPLKVKRNFn---------------------- 214 
170762156  173 SHHIQQQKHLEQQISQQqnf-----------------------ynnQKANFNYYKNP----------------------- 206 
193216948  175 VENFDKFKKEEANNTPSstsn---------------------qpyrRSKAKAIEMDI----------------------- 210 
269115238  172 DGWIEQFNNLKDNENNLkesfs-------------------ksnfySKKESARPIEM----------------------- 209 
291320001  183 QELLKKMIELDSSSdky--------------------------dsyDSNPLKVKRNFn---------------------- 214 
15674106   291 vnhilelkmadetstfmiskwgrkdeeiaqfdqivstvkamnekiiadrtdgednftdslsdalwlrvqgniehdkykdd 370 
71894029       --------------------------------------------------------------------------------     
12044881       --------------------------------------------------------------------------------     
13357937       --------------------------------------------------------------------------------     
13507773       --------------------------------------------------------------------------------     
148377333      --------------------------------------------------------------------------------     
170762156      --------------------------------------------------------------------------------     
193216948      --------------------------------------------------------------------------------     
269115238      --------------------------------------------------------------------------------     
291320001      --------------------------------------------------------------------------------     
15674106   371 lvltanavveikpkptidrvalqikavksdkiqlgreikNNEPVTPMRSVSefSTN---GPVVFEGYVFKGELREIKSR- 446 
71894029   206 ---------------------------------------REIQFFSIKELNenFSSlekEQISVKGTIYKKELLFKNNN- 245 
12044881   217 ----------------------------------------ATEFIPIHKIN--QQI---DDVKIIGQIFELKTHESLTG- 250 
13357937   208 ----------------------------------------NKTITKLIDIN--PLM---NNAKIRAYVFLKKIDILKSG- 241 
13507773   208 ----------------------------------------STEFVPIHKIN--QQM---DEIKLMGQIFELKDFPGYNNl 242 
148377333  215 ---------------------------------------KSYTTYSIKDLAtaPNR---INVEFVGLLFASKKSFSKNK- 251 
170762156  207 ---------------------------------------SNKTITKLIDIN--PLM---NNAKIRAYVFLKKIDILKSG- 241 
193216948  211 ----------------------------------------KSALNSYADLI-----------TLKGEVFSIDVRKFSSG- 238 
269115238  210 ------------------------------------------------DLTtaNETfeeIKITTKGEVFFIESKVLKNK- 240 
291320001  215 ---------------------------------------KSYTTYSIKDLAtaPSR---INVEFVGLLFASKKSFSKNK- 251 
15674106   447 KTgnisyLLEFEM--TDYT--SSFYVQKWL-RGE---EEIQLAKQIKAGLWCRVRGNVQR--DNFKNDLVLQL---TDLI 513 
71894029   246 -------FEKHNLfiTDYD--DAIKLIASK-SSK---VKNEFLDNLEVGKTFIFYCYVDT--DQRGNKYIQI----TKVN 306 
12044881   251 KK-----TLNIYV--TDFQlgGSLILKWSY-------TDEKKIEGITIGNWIKAHIQVER--DPNTQILYGIV---REIN 311 
13357937   242 AI-----AYKLNV--IDDS--ETLTIMTYLpSGEh--PLKKFLDELKIDQLIEAEIDIVL--DNMSKSGQVPI---GKIK 305 
13507773   243 RN-----TLNIYV--TDFQlgGSLILKWFY-------KDPKTIEGIKIGTWVKATVKVER--DAKTQLLQGII---KEIS 303 
148377333  252 KL-----TIQFKV--SDFQ--SAVNCTWFL-DTDwlsNEQKNLINPDNQSWVKVKGSIPSaeKIKGNNFFIYV---DSLE 318 
170762156  242 -------AIAYKLnvIDDS--ETLTIMTYLpSGEh--PLKKFLDELKIDQLIEAEIDIVL--DNMSKSGQVPI---GKIK 305 
193216948  239 KS-----MASFGL--SDYN--EAIIIKVLL-EDN---EELK----ITNGETVIVTGKLTD--DQYSKTKIVFCgstKNII 299 
269115238  241 KI-----LYTLKI--SDYK--EAILVKKFY-------DSENEIPDIKVGDTIIVTGKLSD--DNFTKSKVLIAmgkECFI 302 
291320001  252 KL-----TIQFKV--SDFQ--SAVNCTWFL-DTDwlsNEQKNLINPDNQSWVKVKGSIPSa-DKIKGNNFFIYvdsLELT 320 
15674106   514 EIPTQN---VREDKs-DEKRVEFHAHTNMSQMDAIPSASSLVAQAAKWGHKAIAITDHGGLQSFPEAHSAGKKNG-VKII 588 
71894029   307 TSPDLR---EYSTDhqKIKRIEFNCKSKNNTLDGLLTPEEIVAEAKRQGHSAVGISDYNSIFSFPEFYYAAKANN-IKPI 382 
12044881   312 PVEIPNnykRLDLS--KQKRVELVFHTKMTAFDGINDIEEYAQFAKERGWKAITVTDKDNIHIYPKFYEVAKKYD-LKAI 388 
13357937   306 KICCVE---DKHVKkqITPRLELNFHTKMSSLDAIISTQELIDFAVKNQLKTIGITDRNVVQAYPEIAKFSKKQD-LKII 381 
13507773   304 PIETPAyyrRPDQD--KQKRVELVFHTKMSAFDGINSVQEYAQFAKERDWKTIAVTDKDNIHIYPTLYEVAKKYG-LKAI 380 
148377333  319 LTDSPLn-iKEDIVseDRKRVEFHISTKMNTMDGLFNADDFVERAKRWKMPAVGIMDTDGAQGYPKLFNKAKKAG-IKAI 396 
170762156  306 KICCVE---DKHVKkqITPRLELNFHTKMSSLDAIISTQELIDFAVKNQLKTIGITDRNVVQAYPEIAKFSKKQD-LKII 381 
193216948  300 VTEGLQ---RLSDDneENKRIEFALRSNMSTQDGISSPSAYLKAAKHFGHRAIAITDLDDVQSFPEFYNATKKDKsVVPI 376 
269115238  303 KTEPLQ---KLIEDneDNKRVELAARSNMSAQDGISTPSDYIDAAKFYGHKAIALTDLDDVQGFPEFYNYAKKQKdVKPI 379 
291320001  321 DSPLNI---KEDIAseDRKRVEFHISTKMNTMDGLFNADDFVERAKRWKMPAVGIMDTDGAQGYPKLFNKAKKAG-IKAI 396 
15674106   589 YGVEANLVEDKIPIVYNET-D-VDMYESTYVVFDVETTGLSAVHNDLIQIAATKMHKGNPI-DEFDEFINPGYRLSEFTT 665 
71894029   383 YGAGFAMLEDTNGAFLTEFqN-QDLITGRYVVFDIETTSLSAYHGEIIEFAATIIENKAVV-DKVDIFIKSKEKLSHFTT 460 
12044881   389 YGLEFNLTDDHIKIVHNPD-N-TKLSDATFVIFDIETTGLHGRYDDVIEFSARKIKNNSEI-DHQQFFLKIDKPIPKTIT 465 
13357937   382 YGLETEELEDQIPLVLNVR-D-QNLDNATYVIFDIETTGLFPNFDEIIEFGAVIMQNNKQIgEKIQFFIKPIQQINENVT 459 
13507773   381 YGLECNLIDDHIKIVSNPD-K-TKLKDATFVIFDIETTGLHGRYDSVIEFAGIKVKHNREV-ERMQFFLKIDGPLPAAVT 457 
148377333  397 YGTAFTTINKANEAILGNV-PnGNFKDYSYVSFDIETTGLSPKFHEIIEFGAVDINQDLKVgEVTQFFIKPQAKIGAFTT 475 
170762156  382 YGLETEELEDQIPLVLNVR-D-QNLDNATYVIFDIETTGLFPNFDEIIEFGAVIMQNNKQIgEKIQFFIKPIQQINENVT 459 
193216948  377 YGATISSISSDNGFFYGTP-AdFDLSSQTYVVFDLETTGLSPRFNEIIEFGASIIENGIIK-ESHQFFIKPTKPIPPSIT 454 
269115238  380 YGATLSTIDSDKKFFYNFK-N-FNLKEEEYVVFDLETTGLSPRLDDIIEFGATIVKNNTIT-QKIQFFLQTKRELSAFTV 456 
291320001  397 YGTAFTTINKANEAILGNA-PnGNFKDYSYVSFDIETTGLSPKFHEIIEFGAVDINQDLKVgKVTQFFIKPQAKIGAFTT 475 
15674106   666 ELTGITDDHVK-NAKPLYEVLTKFQKFCEGTILVAHNA-TFDVGFMNMNYSRNGLPIITQPVVDTLEFARNLYPEMKRFG 743 
71894029   461 RLTSITNEMLDqKGIELKEALQKIYDVLNNNVAVAHNA-NFDYNFLIEKFDQNNMQAPKCTFIDSLVVSRILFEHRDKHN 539 
12044881   466 EITKITDEMLE-GGIDQQQGLEKIRNYLDDCVMVAHNGiNFDLPFLQTQFEKYNIKPLTNPLIDTLCLSWALNPLFSSHT 544 
13357937   460 NLTNISQEMVN-NAIDEKTALLKIKEIFDDHILVAHNGiNFDINFINQRLLKWGLEPLKNPSIDTLMISRAINP-FKSHR 537 
13507773   458 EITKITQAQLE-DGMEQQAGLEKLRAWLDGCVMVAHNGlSFDLPFLQTQFEKYNIAPLTNPLIDTLALSWALNPGFASHT 536 
148377333  476 ELTGITQQMLDsEGLSIKDGLQRIYDCLDGKVAIAHNA-KFDFNFLKEQFRLNNVPFPNVTVIDTLIASRIGFPNYKRHK 554 
170762156  460 NLTNISQEMVN-NAIDEKTALLKIKEIFDDHILVAHNGiNFDINFINQRLLKWGLEPLKNPSIDTLMISRAINP-FKSHR 537 
193216948  455 EITKITDNTVA-NGYSQEEGVRKIYDILKNRICVAHNA-KFDINVCKENFLKYGLDNSKIIGIDSLAIARFLIDEAKSYR 532 
269115238  457 ESSHINNEMLK-NGYAQEEGIKKIYEILKDKIAVAHNA-NFDINFCKEKFSKLGLDNSKIFGLDTLALSYFLNPDEFRHS 534 
291320001  476 ELTGITQQMLDsEGLSIKDGLQRIYDCLDGKVAIAHNA-KFDFNFLKEQFRLNNVPFPNVTVIDTLIASRIGFPNYKRHK 554 
15674106   744 LGQLTKKFQIGLEHH--HMANFDAEATGRLLFVFLEELR-TRntGWTSLLELNDKLVSEDSYKKVR---PKHVTLYAKTQ 817 
71894029   540 LNEFCRNLSVNYDTEkaHRALYDTEVLADAWIEATLKLK-DIk-QISNFQELSEY-KSDALFSKYF---SLYINTVVKNQ 613 
12044881   545 LSNICSKLKLEFDDErlHRAEYDTEALKKVFFYFKKQLK-EM--GINTLTEIDQNLNKKCQIDLMKrvfTNTAIVYVKNQ 621 
13357937   538 LGAICKKYEVDYNDEsaHRADYDAIVLADVFKVMKNNLFnDF--GITNLSEINTKLQTTMLKNRSF---GNWINLYIKNQ 612 
13507773   537 LSNICAKLKFDFDDErlHRADYDTQALKKVFDYFKEQVE-LM--GITNLEQLDQELNQQCHFELLKrtfTNTGIIYIKSQ 613 
148377333  555 LEDVTSRLGVVYDPNvaHRGDYDAKVLANVWVNIISELN-SK--NIFTFEDLGNF-TSNDLYAKMH---GYEVSTIALNN 627 
170762156  538 LGAICKKYEVDYNDEsaHRADYDAIVLADVFKVMKNNLFnDF--GITNLSEINTKLQTTMLKNRSF---GNWINLYIKNQ 612 
193216948  533 LEIVAKKFNVYYARNeaHRADYDANVLANVWILMILKLArEK--NIRTANELAAV-NDDKLFAKKF---PREVRVIAKNQ 606 
269115238  535 LGYVAKRFNIIYDTTvaHRGDYDANVLAKIWIKMIDKLAkDY--NILNSQDLNNV-DSQKILSHKF---TYETRILVKNQ 608 
291320001  555 LEDVASRLGVVYDPNvaHRGDYDAKVLANVWVNIISELN-SK--NIFTFEDLGNF-TSNDLYAKMH---GYEVSTIALNN 627 
15674106   818 EGLKNLFKIVSFGNVKYYAGLPRVPRSV-LEANREGLLVGSACEIGEVFDAAINKTFEETLEIAKFYDFIEVFPPALYRS 896 
71894029   614 AGLKELFQLVSIANTKTFYGAPKIFWST-LKSFKN-ILVGSNGVQGELFDILLLSSRQRVEKYIQKLDYIEIPHPDLFDS 691 
12044881   622 RGFQNLYEMLSIALTDHNANRPLVLASS-LAKFRKSFLLTENPVQGDIFKAALTKPINELEKAIEKVDFVLISQPNAYLG 700 
13357937   613 ANVKDMYELVSISHTDMYYTRPTITTSF-LANKKDKLIISNSIHESDLINALYSKNDEEIKRLIQRYDFITLPSLGSQKH 691 
13507773   614 SGFAKLYELLSIALTDNNATRPLVLTST-LQKFAKSFVITDNPVQGDIFKAALTKPLKELEAAIKRVDFVLIAPPGAYAG 692 
148377333  628 KGLKKQFELITDCLTKKFINGPITFKEDfVNLDRSDVLVGSGTLKGLLIDKYFYSSHDDFIKELKHYDFIEIPAPQCFEH 707 
170762156  613 ANVKDMYELVSISHTDMYYTRPTITTSF-LANKKDKLIISNSIHESDLINALYSKNDEEIKRLIQRYDFITLPSLGSQKH 691 
193216948  607 KGLKKLFKIISKSLTDDYHGGPRLFIDK--WEHDEDLLLGTSTNAGWVWEEAMTGTDENILKALAPYDYIEFPPISTFNY 684 
269115238  609 AGLKKLFKIISRSLTSQFKKNPQIYFDQ--LGNDEDLFFGSATNQSYVWDQVFTGTNENLLNSLKYYDYIELPPISSFQY 686 
291320001  628 KGLKKQFELITDCLTKKFINGPITFKEDfVNLDRSDILVGSGTLKGLLIDKYFYSSHDDFIKELKHYDFIEIPAPQCFEH 707 
15674106   897 LVVGGSFKSEKELEQTLKDLIKIGKTLGKPVLATGNLHYLNPEDAIYREIIVRSLGLGAEINWtqghg-----ehakpLP 971 
71894029   692 YLDRNQLTKDQLLESL-QILISLAKKHNKLIISTAEPRYRHKGDREIFKVLT-----SFPIRDkrhflwnykavkagnYS 765 
12044881   701 YTLREGLK-KELINDAIKLVIKTATKLKKLVAVASDAYFIHPWENEYYKAIVCAKGLGGKWHRhfnn-------kekeQT 772 
13357937   692 LVYAKKI-TIENVQKAFKKLIYLALELNKIIIYSSSPYYFFKDDKKFYDVYVNTKGLEGKAHRfa-----------neVY 759 
13507773   693 YTIREGLKKEA-IPNAIKLVVDTAQRLNKLVAVASDAYFIHPWENEYYKAIVCAKGLGGRWHRhfny-------kereQR 764 
148377333  708 WIKYGFI-TTKQLHDGLSEIISEAKKHSKICIATADVKYLDPWDKEIFMSLVYAKGIKNARHYlfdykk----aeegkLV 782 
170762156  692 LVYAKKI-TIENVQKAFKKLIYLALELNKIIIYSSSPYYFFKDDKKFYDVYVNTKGLEGKAHRfa-----------neVY 759 
193216948  685 IYKDDSI-TLEQVQFAYKDLLEKAKKLGKLCIAVSDARYIYDYQSLIYRIYVNAPTLGGGQHWlkk---------yreIA 754 
269115238  687 MIDSNHV-TLDELKFLYKDLISKAKSLNKMCVAVSDCRYIYNYQRLIHEIYIEAPTLGGGLHWlk-----------krPS 754 
291320001  708 WIKYGFI-TTKQLYDGLSEIISEAKKHSKICIATADVKYLDPWDKEIFMSLVYAKGIKNARHYlfdykk----aeegkLV 782 
15674106   972 LPEAHFRTTDEMLEAFSFLDE-KTAREIVIDNTQKMA-DEFD--V-LTPVRDDLYTPKMvfdggETSEERIVRLTYEKAH 1046
71894029   766 VPNFYFLTTDEMLDAFSFLKDkSLIEDIVVNNAHKLN-NLID--EnIEVIKTDLYPPSI-----KNSSELLKDLVYKNAK 837 
12044881   773 VPEVFLHTTDEMLKRMSFLGE-DIAYKLVVENTNKIV-KLLDlnE-LVPTKNKLYPPVM-----QDSNQKLIDKTWKQAE 844 
13357937   760 VPDLEYIDQKNAIDELAYLEDeKLINLIINENPVHIN-SWFD--DsIQPLKEGLYAPKM-----EGVDQKTIDYVYHTAK 831 
13507773   765 VPNVFVRTTGEMLNEMSFLGE-QLAYELVVENTNKLAkQLTA--DdLVPVQTKLQPPVI-----EGSNENLAAKTWSQAK 836 
148377333  783 IPNQRFLTTDEMLEQFAFLNDkKLAEEIVIDNTQKIA-NMAE--N-IEVIKTGLFTPEF-----DDSKKKLHDLVYKNAH 853 
170762156  760 VPDLEYIDQKNAIDELAYLEDeKLINLIINENPVHIN-SWFD--DsIQPLKEGLYAPKM-----EGVDQKTIDYVYHTAK 831 
193216948  755 TPDFKYLTTRQMKDEFKFLNDgTLINEIVVDNTHKLA-EQIT--PkIEVIKDKLYFPTF-----DDSANKLKEVVYQTAK 826 
269115238  755 HPEFRYLTTREMLKEFAFLNDsYLINEIVIENPNKIA-NEIS--SnIQVIKDKLYVPTF-----DNSPQKLREVVYRTLK 826 
291320001  783 IPNQRFLTTDEMLEQFAFLNDkKLAEEIVIDNTQKIA-NMAE--N-IEVIKNGLFTPEF-----DDSKKKLHDLVYKNAH 853 
15674106  1047 EWYGNPLPDIIDARLEKELRSILGNGFSVVYIISQELVKRSNDRGYIVGSRGSVGSSLVATMIGITEVNPLAPHYRCPEC 1126
71894029   838 KKYGEVLPKLVQDRIDKELIPIINYKFDVVYWISHILVKKANDDGYVVGSRGSVGSSLIANLINITEVNPLEPHYICDNC 917 
12044881   845 KRYGKNLPKLIKERIEKELNAIISNGFGIVFWISHLLVEQSVKDGYFVGPRGSIGSSLIANLIGISEINPLAAHYLCEQC 924 
13357937   832 KIYGENLPTIVEQRIKKELNSIIKHGFSVVYWISHLLVEKSMQDGYGVGSRGSVGSSLVATFLNITDVNPLTPHYLCPNC 911 
13507773   837 AIYGDPLPKLIEQRIQEELKAIIDNGFGIIYWISHLLVKQSVQDGYFVGPRGSIGSSLVANLIGISEINPLVPHYLCESC 916 
148377333  854 AKYGENLPELIQKRIDSELNPIIKYGFDVIYWISYKLVKLSIDQGFIVGSRGSIGSSFVASLIGISEVNPLVPHYCCPKC 933 
170762156  832 KIYGENLPTIVEQRIKKELNSIIKHGFSVVYWISHLLVEKSMQDGYGVGSRGSVGSSLVATFLNITDVNPLTPHYLCPNC 911 
193216948  827 ERYGNNIDEKILSRIEKELGPITKYGYSVIYWISHKLVKRSNQDGYLVGSRGSVGSSIVANLAGITEVNPLKPHYLCEKC 906 
269115238  827 ERYGDNPDPIIVKRIEKELNPIIKYGYSVIYWISHKLVKKSNEDGYLVGSRGSVGSSIVANLAGISEVNPLPPHYLCKNC 906 
291320001  854 AKYGENLPELIQKRIDSELNPIIKYGFDVIYWISYKLVKLSIDQGFIVGSRGSIGSSFVASLIGISEVNPLVPHYCCPKC 933 
15674106  1127 QYFECYDDGSFGSGYDMPDKNCPKCDHK--LIKDGHDIPFETFLGFKGDKVPDIDLNFSGDDQPLAHLDVRDIFGEDYAF 1204
71894029   918 KHFEVVNNDKITSGYDLDDKNCPNCDSI--MDKDGHSIPFETFLGFKADKVPDIDLNFSGEYQIAIHNYTRELFGEDKTF 995 
12044881   925 HYFEV--SDSVDDGYDLMIRDCPKCHEKasFKGDGHNIPFATFMGFSGDKIPDIDLNFSSEYQAKAHDYVRKLFGVNNTF 1002
13357937   912 KKCEFITNAD--DGFDLAPKSCEQCQTP--MLTDGHNIPFETFLGFDGDKVPDIDLNFSGVYQAVAHNFIKSIFGETHSY 987 
13507773   917 QYFEV--NEEVDDGYDLMVRDCPKCGAKaaFKGDGHNIPFATFMGFAGDKIPDIDLNFSSEYQAKAHAYVRELFGEQYTF 994 
148377333  934 KHFEIANVSGITSGYDLPDKTCPQCHTK--IKGDGQSIPFETFLGFNADKVPDIDLNFTGEFQGVVHEEILKLFGESHTF 1011
170762156  912 KKCEFITNAD--DGFDLAPKSCEQCQTP--MLTDGHNIPFETFLGFDGDKVPDIDLNFSGVYQAVAHNFIKSIFGETHSY 987 
193216948  907 KHFEWSEDPHIFSGWDLPDKKCPKCATI--MLKDGHDIPFETFLGFEANKVPDIDLNFSGEYQVTIHNYVKELFGEAHTF 984 
269115238  907 KYFEWNSNKEIYSGWDLPDKHCPNCNSI--LSKDGHNIPFETFLGFEADKVPDIDLNFSGEYQPTIHNYVKELFGEAHTY 984 
291320001  934 KHFEIANVPGITSGYDLPDKICPQCNTK--IKGDGQSIPFETFLGFNADKVPDIDLNFTGEFQGVVHEEIRKLFGESHTF 1011
15674106  1205 RAGTIGTVAEKTAFGFVKGYERDYD----QFYGNAEIDRLAAGSTGVKRTTGQHPGGIIVIPNYMDVYDFSPVQFPADDV 1280
71894029   996 RAGTVSSIQYRKAFGFIKKYIEDTN----TFYSNGFIDYLAEKCIDVKVTTGKHAGGIVVLPENLDIEEFTPVNYASDGL 1071
12044881  1003 RAGTIATVAEKTAYGYARNYFEIIKr--vDLATTAEIERFKQKLIGIKRTTGQHPGGIMIFPSDHSVYEFTPCGFPADDV 1080
13357937   988 RAGTIGTMAQTSAENTVKKYFENRFne-nKIIRDSTVSLYVQKCIDSKRTTGQHPGGIIIVPKEYSIWDFSPYNFPANDI 1066
13507773   995 RAGTIATVAEKTAYGYARNYFEIIKq--tELATAPEIERFKQKLVGIKRTTGQHPGGIMIFPNHKSVYEFTPCGYPADDT 1072
148377333 1012 RAGTISKVAEKTAFGYVKSYAEQTR----QNIPQIFVEFLANRIKDVKRTTGQHPGGIIIIPKQFDIFDFTPINYPANDQ 1087
170762156  988 RAGTIGTMAQTSAENTVKKYFENRFne-nKIIRDSTVSLYVQKCIDSKRTTGQHPGGIIIVPKEYSIWDFSPYNFPANDI 1066
193216948  985 RAGTIATIASKTAYGFCRKYDEEIHslheEPWTRTFLDFLASKTEGVKRTTGQHPGGIIIIPKEFDVEDFTPVNYPANDI 1064
269115238  985 RAGTIATVAEKTAYGFCKKYEEEKRgn-yQPWSHLFLDFLASKTQGVKRTTGQHPGGIIIIPKEFDVEDFTPVNYPANDT 1063
291320001 1012 RAGTISKVAEKTAFGYVKSYAEQTR----QNIPQIFVEFLANRIKDVKRTTGQHPGGIIIIPKQFDIFDFTPINYPANDQ 1087
15674106  1281 -NAEWQTTHFDFHAIHDNILKLDILGHDDPTMIRKLQSLSGIVPQDIPMDDPGVMKLFTGTESLGLT-EEQLGVK-LGTL 1357
71894029  1072 eDKEWKTTHFKYDFLKENLLKLDLLGHSDPTQIRFLEQATGLLSKNIPKKDKNLLKLFSSTEPMEID-PNDINGEtTGAI 1150
12044881  1081 -ESEWKTTHFEYDALGDAILKLDILGQDDPTMLKHLADLTKINPQNIPHFDKNLISMFSSNKPLNLK-PGIVDEV-TGAV 1157
13357937  1067 -NETWKTTHFAFEYLHDSLLKFDILGHDNPTILKLLKDYTGIDERDVPMYDPLVMKSFSDISALNIKpSDVLNET-TGAI 1144
13507773  1073 -SSDWKTTHFEYDALGNTILKLDILGQDDPTMLKHLGDLTHVNPQNIPRFDKKLTEMFWSVNPLKLK-PHYLDEP-TGAI 1149
148377333 1088 -SSSWLTTHFDYKAIHDNVLKFDILGHDNPTSIKLLEQYTGINIYDVPKNDESVIKLFSSTEPMGIK-PDQISNEkTGAI 1165
170762156 1067 -NETWKTTHFAFEYLHDSLLKFDILGHDNPTILKLLKDYTGIDERDVPMYDPLVMKSFSDISALNIK-PSDVLNEtTGAI 1144
193216948 1065 -TSAWKTTHFDFTSIHDNVLKLDLLGHDDPTVIRMLEDLTKTDAKKIPKFDEKVMSLFSSTEAIKIN-PSEISNEtTGAY 1142
269115238 1064 -ESSWKTTHFDFTSIHDNVLKLDLLGHDDPTVIRMLETLTNTNAKEIPKFDAEVMKLFYTTESLKIS-PSDIGGEtTGAY 1141
291320001 1088 -SSSWLTTHFDYKAIHDNVLKFDILGHDNPTSIKLLEQYTGINIYDVPKNDESVIKLFSSTEPMGIK-PDQISNEkTGAI 1165
15674106  1358 GIPEMGTFTSMNMIAEAKPKNFADLLQISGLSHGTDVWSGNAQDLIRSGIADLSSVIGCRDDIMVYLIHKGLENGLAFTI 1437
71894029  1151 ALPEFGTKFTREIIKTSKPHLFADLISISGLSHGQNVWKNNAEDLILNENKTLNEIVCCRDDIMNYLIKKGVDASLSFKV 1230
12044881  1158 GIPEFGTKFVRKILEQTKPKDFADLIRVSGLSHGKNVWADNAQKLIKSNRLTLRDVIACRDDIMLYLINKGMQAKDAFEI 1237
13357937  1145 SIPEFGTRFVRGMLVDTKPKSFADLIRISGLSHGESVWLGNAQSLIKSGKL-LKDVIACRDDIMTYLIRQNVEPKTAFLI 1223
13507773  1150 GIPEFGTKFVRKILEQTKPKGFGDLIRVSGLSHGKNVWADNAQKILKDQNLSLKDVIACRDDIMLYLIHKGMQAKDAFEI 1229
148377333 1166 GLPEFGTSFVRQMLNDIKPKTVADLISISGLSHGTNVWINNADELVLEKGRKLNEVVCCRDDIMPMLIAKGIEPLMSFTL 1245
170762156 1145 SIPEFGTRFVRGMLVDTKPKSFADLIRISGLSHGESVWLGNAQSLIKSGKL-LKDVIACRDDIMTYLIRQNVEPKTAFLI 1223
193216948 1143 GLPEFGTTFVRRMLKTAKPKSFNDLILMSGLSHGTDVWSGNAEELIKQG-KKLQDCVCCRDDIMRDLINWNIDHLEAFEI 1221
269115238 1142 GLPEFGTNFVRKMLKKAQPRSFNDLILLSGLSHGTDVWTDNAEELVARG-KKLIECVCCRDDIMRGLIEWNIEPLTAFQI 1220
291320001 1166 GLPEFGTSFVRQMLNDIKPKTVADLISISGLSHGTNVWINNADELVLEKCRKLNEVVCCRDDIMPMLIAKGIEPLLSFTL 1245
15674106  1438 MERVRKGMwnkipaEEREKYVEAMREHDVPEWYIESCSKIKYMFPKAHAAAYIMMALRVAYFKVHHPILYYCAWFSIRAT 1517
71894029  1231 TESVRKGK------GVDSEDIKILSTYNIPDWFFDSMQKIKYMFPRAHAVAYVIMAWRMGYYKLYYPLEFYASFFSVKCS 1304
12044881  1238 MEKVRKGI------KVNAKEVSLMQNCGVEQYWINACLKINYLFPKAHAAAYVLMAWRIAWFKLYHPLSYYACLLSFKLK 1311
13357937  1224 MEDVRKGK------KIKPEHQIILKELKVPEWYIESANKIKYMFPKAHATAYVMHAWKFAWYKIYYPLEYYAAFFSVRAD 1297
13507773  1230 MEKVRKGI------ALNAKEVQLMQSNGVEQHWINSCLKISYLFPKAHAAAYVLMAWRIAWFKLYHPLSYYACLLSFKLK 1303
148377333 1246 MEKVRKGK------GLSNEEVGLLEKHNVPDWLIKSMQKIEYLFPKAHATAYVTMALWIAWFKLYEPLAFYASYFTAHSK 1319
170762156 1224 MEDVRKGK------KIKPEHQIILKELKVPEWYIESANKIKYMFPKAHATAYVMHAWKFAWYKIYYPLEYYAAFFSVRAD 1297
193216948 1222 MEKVRKGK------GLSEYQESLLQSKNVPIWYIESLKKIKYMFPKAHATAYVIMAWRIAWYKFYYPLQFYASFYSTRPD 1295
269115238 1221 MEKVRKGK------GLTPEWEELLKSHNVPEWYIESLQKIKYMFPKAHATAYVIMAWRIAWYKLYYPLPFYASFYTNRPD 1294
291320001 1246 MEKVRKGK------GLSNEEVGLLEKHNVPNWLIKSMQKIEYLFPKAHATAYVTMALWIAWFKLYEPLAFYASYFTAHSK 1319
15674106  1518 AFDIGVMGA--G--LEAVKAKMKEI--K----DKGFDATNVETNLYTTLELCNEMLERGFTFGKIDLYRSEATEFVI--D 1585
71894029  1305 KFDLSAMIDfsKdgYWKIKNKIEEIekLi--rTNNKKDNKKEEDILESLNVALEMYSRGFTIQNIDIEKSDAYNWIIdkD 1382
12044881  1312 EHDINGFEK--G--YEFIKNRLDELnkL----YRIKKIKPKEAELLTSYEVYLEMMARNIKLQQISIQNSNARMFVE--H 1381
13357937  1298 NFDLFVINQ--G--KEFIEKTYNDIeqRsksrDPQKKVSSRELALQPIYEIVIELLARGFKISNISIEQSQATSYVIdkE 1373
13507773  1304 EHDVSGFKS--G--VSFVKQKLEELntL----YRIKRIKPKEAELLTSYEVYLEMMARGIKLEQISLTHSHATRFVE--H 1373
148377333 1320 ADDIENMIDkpN--GIKVSKRLYEL-------KKTEDRSNKENDLIGVFEVAEELYARGFYISNVDIDKSQAEKWLIdkE 1390
170762156 1298 NFDLFVINQ--G--KEFIEKTYNDIeqRsksrDPQKKVSSRELALQPIYEIVIELLARGFKISNISIEQSQATSYVIdkE 1373
193216948 1296 AIDIKVMSD--G--KDAVDNKLLELkkRsd-sKK-EPLSTKETNLIPILEITQELYARGFKITNVHISKSKAARWIVdiE 1369
269115238 1295 AIDIQIMSS--G--AASVHQKLIELknRq--nSTGEKLSVKEEALIPVLEITQELYARGFKIKNVDLKLSLADKWIIdeK 1368
291320001 1320 ADDIENMIDkpN--GIKVSKRLYEL-------KKTEDRSNKENDLIGVFEVAEELYARGFYISNVDIDKSQAEKWLIdkE 1390
15674106  1586 GDTLIPPFVTMDGLGENVAKQIVAARAEGEFLSKMELRKRGGVSQTIIENMTNMGVLEGMPD-DNQLSLF 1654
71894029  1383 SKSLIPPFSALDGIEAGAIK-IINARKERPFKTVLDFAKRSGVSSTIVEKLKELNVFKDLPE-SEQLSLF 1450
12044881  1382 NGVLIAPFITIPGMGEAVASSIVEARNEKPFASLNDFKKRTKITKKHVETMEQLQLFDEFEH-QDDHKLF 1450
13357937  1374 NNAIIPPFIAIQGLGETVANSIIEARNQKVFSTIEDLKNRTKISRTDLKNLRVLGVLDHLSE-TEQLTLF 1442
13507773  1374 NGMLIAPFITIPGMGEAVANSIIEARNEKPFSSLDDFKKRTKITKKHIEAFTQMQLLDEFREqDNQKKLF 1443
148377333 1391 RGCLIPPFSTIESLGSVKANDIVNARAEKAFLSKEDFKIRTGVSKTVFDTMNRMKILDSLND-SDQLTLF 1459
170762156 1374 NNAIIPPFIAIQGLGETVANSIIEARNQKVFSTIEDLKNRTKISRTDLKNLRVLGVLDHLSE-TEQLTLF 1442
193216948 1370 NKALIPPFVVVEGLGETVADSIIQARNEHEFLSVEDFEKRTKVNSKIASQLKLLGILDELDE-TNQNSLF 1438
269115238 1369 DKALIPPFNVVDGLGITVAQTIVSARKEGFFLSIEDLASRTKVNSRIISELKKIGVLDCLDD-TNQVSLF 1437
291320001 1391 RGCLIPPFSTIESLGSVKANDIVNARAEKAFLSKEDFKIRTGVSKTVFDTMNRMKILDSLND-SDQLTLF 1459
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