Conserved Protein Domain Family
MidA

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COG1565: MidA 
SAM-dependent methyltransferase, MidA family [General function prediction only]
Statistics
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PSSM-Id: 441173
Aligned: 303 rows
Threshold Bit Score: 264.365
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_015153051   1 Mtdd-----snLELKQAIRRAIAsssQQRITFAEYMELALYHPTCGYYTTkAVQMGKQGDFFTSTHLGADFGELLAEQFV 75 
WP_012462129   1 M-----------EIEQHIRQIIRs--ENNITVENLMSIVMESRYNSYYRI-QQPLGKAGDFITAPEISQMFGEMIGIWCI 66 
WP_011642700   1 ------------MIADTLRDRIRs--GGPISIAAFMTEALFDPRHGFYAT-KDPIGAVADFITAPEISQMFGELIGLVAA 65 
WP_012778167   1 Mnav----skqPTLEERLKSLIKt--DGPISLSVFMQLALFDRKQGYYAT-RPGLGK--DFTTAPEISQIFGEMLGVWAA 71 
WP_013047066   1 MtiasgneinaDDMTASLVAQIVa--DGPLSLARYIEIALSTADAGYYQS-SDPFGHKGDFITAPEISGLFGEMCGLFLA 77 
WP_013419355   1 Mpsdas-dsglTPLALKLRRDIAe--RGPIPLHDYMEACLYDLQHGYYRK-RDPLGRGGDFITAPEISQVFGELIGLWAA 76 
WP_013946576   1 Midng--lrrdTPLARRIKERIRr--DGPMTVDSYMSACLWDADYGYYRR-QQVFGASGDFITAADVSQVFGELLGVWAG 75 
WP_045370137   1 Me--------sTLLSVRLKAQIAr--IGPITVERYMDVCLADTTAGYYPS-KQPIGAAGDFVTAPEVSQMFGELLGLWAY 69 
WP_046479230   1 Mnydpd-arrdTPLSCNLIARIKr--DGPLTVRQYMTACLQDADHGYYRR-REAIGRTGDFITAPEISQIFGELIGLWSA 76 
WP_099340628   1 --------------MNLLEKLIYk--KKVITLDKFIDIALYNKQLGYYQT-KKIFSRDGDFITSPLISSIFSEMISIWIV 63 
WP_015153051  76 QMWQ-ILGKPQ-------PFTLVEMGAGQGFLVLDLLKYVQLNYPEFFAVLDYIIVEQSPALRELQQQTIPPTPlekggk 147
WP_012462129  67 DLWH-KLNRPQ-------KIDLIELGPGKGTLLCDILNATRHI-KKFSTAISLTLVEINCSLKKIQQDNLLSFNv----- 132
WP_011642700  66 QTWL-DMGRPA-------AFKLIEMGPGRGTMMSDALRAARTV-PGFMDATEIMLIEASAALKAVQAQTLGPSGa----- 131
WP_012778167  72 HEWQ-QMGCPS-------PFYLIEMGPGRGIMMKDIWRATAKI-AGFHDAAHPYLIEPSPSLRKIQAKRLSALK------ 136
WP_013047066  78 HMFE-LGKAPEetesgrkKPVIIECGPGRGTLMADMRHVWGQLMP-ELAACTVHLIETSPYLRTLQEQALPDa------- 148
WP_013419355  77 QVWM-QMGQPQ-------SVCLVELGPGRGTLMADALRAARVM-PGFLQSIAVHLVESSEVLREAQKATLAGVPv----- 142
WP_013946576  76 VVWQgVLGAPN-------PITIVEYGPGRGTMMRDILRAARIV-PGFSNVTRVHLVEASESLIELQTATLSEFRh----- 142
WP_045370137  70 AVWQ-SMGSPH-------PVILAELGPGRGTLMADALRALRRL-PGFMDSVHVALVETSPPLRRAQEEALAGSGa----- 135
WP_046479230  77 VVWQ-QMGGPS-------RINLIELGPGRGSLMRDALRALRLV-PDFLSAANVHLVESSETLRAAQTETLGAIDl----- 142
WP_099340628  64 SYWI-YLKKPK-------QINILELGPGNGLMINQIINSLKKI-KTFDAKFTIYLHEKSESLVKVQKKNLNIFK------ 128
WP_015153051 148 tipptplekggktipptplekggktipptplekggnvlsttpflrgsppaggSIRWCS-LEEIpDnSiaG--CFFSNELI 224
WP_012462129 133 ----------------------------------------------------PIKWVKsVNHIvS-S--YptIILANEFF 157
WP_011642700 132 ----------------------------------------------------QIRWIDrLDAA-A-P--GpcFIVGNEFL 155
WP_012778167 137 ----------------------------------------------------NPQWVNeLTDI-P-N--GpsIILANEVL 160
WP_013047066 149 ----------------------------------------------------VIHWHDdLSAL-P-A--AplYGIANEFF 172
WP_013419355 143 ----------------------------------------------------PIQWHGdMGEV-P-S--GpaIVIANEFF 166
WP_013946576 143 ----------------------------------------------------VLSWGReLDEI---N--PpaIIFANEFL 165
WP_045370137 136 ----------------------------------------------------EISWHDtIENV-P-A--GplIVLANEFI 159
WP_046479230 143 ----------------------------------------------------PINWHPrLEDV-P-E--GptIVIGNEFL 166
WP_099340628 129 ----------------------------------------------------NIIWTKnINEI-K-Q--YptIIIANEFF 152
WP_015153051 225 DALPVHQIAIERGV------LREVYVGQ------G-KQggqgssnsshqplatshsPFTEI-TEKLSTPRLQEYFDLVgI 290
WP_012462129 158 DALPIKQYIKKINQqsgqinWLERVVKI------DnNN------------------KLYFD-TIDADINE-HKF-LKL-H 209
WP_011642700 156 DCLPVRQALRHKGE------WHERLVGLaptygnDsES------------------DFVFV-LGPPLGQD-TDLIPER-L 208
WP_012778167 161 DCLPIRQFIRQDGA------WCERKIGL------DkNG------------------NFMLG-ISSPISTE-TENTPDN-L 207
WP_013047066 173 DALPVAHAICRKGI------WRHRLVTA------Tp--------------------ALGFGeGAPLTTAELDRWHLSH-K 219
WP_013419355 167 DCLPVRQFAFDGAAe----vWRERVVAF------E-DG------------------AFHLA-TSADVAQ--PPLTAAS-Y 213
WP_013946576 166 DAWPVAQWVKTASG------WHIRAVTL------DaRG------------------DLQFT-AIDGECPR--DAFEAL-L 211
WP_045370137 160 DALPIRQLIWRDGA------WRERCVRI------AySG------------------GFEFC-DGPALPVE-SLRRNAE-L 206
WP_046479230 167 DALPVEQLIATPSG------WRCRSVTV------DdLD------------------RLQFG-EIALPPSG-RLDIPVH-A 213
WP_099340628 153 DAFPIKQFFKINTK------WHEQCISFk-----NnIK------------------RIIYY-KNKINNN--YLKKYSK-F 199
WP_015153051 291 -DItsstyPDGYRSEVNLAALDWLQAVAQKLQR--GYVLTIDYGYPASRYYNPA-RSQGTLQCYYQHHHhNDPYINIGQQ 366
WP_012462129 210 nNA-----PNGGVLEISPAQHQTIQAVSNLLKKngGGSLIIDYGYDISPEQRKNyQYNSSLQAVKHHQY-HPLLENLGCA 283
WP_011642700 209 rDA-----EDGALVELRPGDRQVVDQLAERFANqpGRALFIDYGPATS-------EIGDTLQAIRAHKK-QPPLQDPGTA 275
WP_012778167 208 sD------MVQDVVEISSALDAFIELISDRLKHdnSRALFIDYGPANS-------TPGDTLRAYSDGKQ-VDPLSNVGNV 273
WP_013047066 220 aAS-----PDGTVAEFCVMGEDIMQVLAAHIARfgGAILIIDYGKTDN--------FGDTVQAVAAHKP-VDLFYQPGQA 285
WP_013419355 214 gEP-----RDGDILEHCPGVGPLLAKFAARAGDapLAALVIDYGYAKP-------AFGETLQAVRRHKF-AGLFDAPGET 280
WP_013946576 212 pGA-----PPGTVIESQ-RLDQLADALQALSERgpIAFLMVDYGHTTP-------AAGDTLQAVRAHKY-ESPLTSPGEA 277
WP_045370137 207 rQL-----PDGSILEVRPAANAVVAALAAKAKDapLAALIVDYGHEAT-------ECGDTLQAISRHKF-VDPLQAPGSV 273
WP_046479230 214 eNA-----PAGSILTV-PNFSELSAPLASLGKSapLAALLIDYGHAAS-------EIGDSLQAVRDHHH-EHPLTSPGEA 279
WP_099340628 200 fNI-----NKSRVIEYPVKIENYINSISKILKKnnGVFLTFDYGYSDS-------IGKNTLRAIKKHKI-VNLLKEYTDC 266
WP_015153051 367 DITAHVDFTALQRWGDRCG--------LPTVGFTQQGLFLMALGLGDRIAALSQtT--SQslQQVLWRRDALHQLLDPMG 436
WP_012462129 284 DLSAHVDFWSLKNIAVAEG--------IASFGSISQNVLLHKLGIKTRLNMLKQ-InsDE--NLASKLDLQYNRLTYVRA 352
WP_011642700 276 DLTARVDFESLMQAGRTAG--------LTAHGPQTQGQWLRDLGLEARAAVLSQ-S--QP--GKRSEIARQIWRLTDTEQ 342
WP_012778167 274 DLTADVDFAKVVQSAKTHG--------LEIAGPSPQGWFLNALGGVERVNALIN-Q--NP--DKIDEISEGAMRIMAPDQ 340
WP_013047066 286 DISHWVDFGALAACASEAG--------ARLIGPVEQGSFLTQIGLKARAEQAAK-Ha-DP--EMRRALLAAYDRLVSPAQ 353
WP_013419355 281 DLTAHVDFSRLARLAEEAS--------FVVFGPMAMGEWLLRLGVEARANQLLA-St-SA--EEARAIAQSIARLVDPAQ 348
WP_013946576 278 DLTVHINFYDLASTLHRAG--------LALDGPVTQAEFLGALGIVERASRLMA-A--NP--ARAAEIETGVARLLAPNG 344
WP_045370137 274 DLTAHVDFGALKDAVRAAG--------LAAYGPKRQRALLLELGLEARLERLCQ-Da-TP--EQRDALVAGADRLIDPAA 341
WP_046479230 280 DLTTQVDFEAVRTQITMSGsenaadpaLVVDGPITQAEFLGALGIVQRASRLMA-A--NP--IEAGNIELGVARLLAPQG 354
WP_099340628 267 DITFDVNFNILKNIFKKNN--------IRHIGTVSQNFFLQKLGIMERATQIIK-Kq-NV--NDSKDLILSINKLINPKE 334
WP_015153051 437 LGG-FGVLIQSR-GLTETevaqplMGLK 462
WP_012462129 353 MGElFKAIAITSaPSIIP------LGFC 374
WP_011642700 343 MGElFKLVCLDSaELPPP------PGFS 364
WP_012778167 341 MGErFQALCLSTkDLPSP------AGF- 361
WP_013047066 354 MGSaFKVALLVPqGDGTP------PGFV 375
WP_013419355 349 MGAlFKILSWTRgISEPP------PPFG 370
WP_013946576 345 MGGrFKVLAARSpGLPSL------PGFS 366
WP_045370137 342 MGVlFKALAITSnDLPAP------PAFE 363
WP_046479230 355 MGTrFKALGVRSgGLPTL------PGF- 375
WP_099340628 335 MGStFQALAFCNkDCKFN------LGFI 356
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