Conserved Protein Domain Family
DUF4241

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pfam14025: DUF4241 
Protein of unknown function (DUF4241)
This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and eukaryotes. Proteins in this family are typically between 205 and 315 amino acids in length. There is a conserved GDG sequence motif at the C-terminus.
Statistics
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PSSM-Id: 433653
Aligned: 38 rows
Threshold Bit Score: 64.1681
Created: 25-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
EFC48838        563 FKVESTSMVVID---------PF-----TTNSGVIIKNVRPGIwnWKTTHKSKDHVDGG----YEDHFLTAQIVaihqdy 624
WP_007070895     48 VTFPTGKIIVCD---------PLvy-ldKNTVPYREK-VPVGT--FMLETLAAEMEEGNf------RYIATRIR------ 102 Dialister in...
WP_083687607     48 CSVPSGELLVRD---------PIrylsnREELPYFVT-SPVGI--YPLEVAFTRTEDGDi------LYLAVRLR------ 103 Negativibaci...
WP_004327342     47 CDLPSGNLLVRD---------PLvylpnRNERPYFQN-APAGK--YETEICVIKSDDEDc-----dRYAAVRLR------ 103 Bacteroidales
jgi:Weevi_1721   46 FTSLSGKLIACD---------PLgfiltDDDKPYYEV-APVGV--FPTYASFITLENPDneaeTVDLIASYKIA------ 107
CBK97746         45 VHFPTGQIFACD---------PLv---eLEDTLPFLQTIPAGT--YPVKICVVPSEQ------YGDRYACVKVE------ 98 
CDC25310         45 VSFPTGTIFACD---------PLi---eLEDALPFIQTIPAGT--YPVKICVVPSEE------YGDRYACVKVE------ 98 
Q5R0R9          207 LQISSGILGILDfgydiyrfePL------------QRRVTPGE--YLVETVT-----------THDRVAGIRVK------ 255 Idiomarina l...
jgi:GYMC10_1075   8 FEVSSGRLVVAD---------PCyeldtniiimgvlEAVLNGTwvGEVEKVEI----------PDWGEANAKLTayh--- 65 
EFC49640        562 FKVESTSIIAND---------SL-----ADGNPVIIENVRPGTwkWITTNKEKNYVDGG----GIDNYLTAQIIaihsdc 623
EFC48838        625 yeelssdpklwlVPN-NVYRKLERNHKVERDeyydDEI-EGGwFvmkLGVGVDVAMAGIFDEKYFNDEKCLELkrkpksk 702
WP_007070895    103 ------------FAE-EEAAYYELALTGTEDl---SDWkNFD-Y---IGFAVDAGLATVADVKVRDAYCKFESdwyeknp 162 Dialister in...
WP_083687607    104 ------------FNY-RPAVHFEQALTGEEEi---ESF-DGG-F---YGFFSESGLGCICDELSHQAFCAFVEkwrqehp 162 Negativibaci...
WP_004327342    104 ------------FNE-KRAVRFYEALVGNENl---ETLeEGD-Y---FGFCVDAGLGCVCDEIIHRIYCDWDEqwrkdnp 163 Bacteroidales
jgi:Weevi_1721  108 ------------FSD-ETPTEYREALRGNEDl---ASLqEDE-Y---FGFNTDSGLATIFDQDAFPEITKLIDrienkgd 167
CBK97746         99 ------------VSQ-EKLVRYELGMVGNEDl--dEELgEDE-Y---FGFGVDAGMGCVADIQTQAAFKAYWAkrleedp 159
CDC25310         99 ------------ISG-QQPVRYELGMIGNEYl--dEELeEDS-F---FGFCVDAGMGCIADIKAQEAFNLYWEqrleeea 159
Q5R0R9          256 ------------LSEsEQAVKWYAANTPSGN----------------GVYGVDAGNLAIFDVANLVELSHFRKeklfnew 307 Idiomarina l...
jgi:GYMC10_1075  66 ----------hsVAEqGAFLEW---------------------IkcpFVAGVDSGQAGIFDIQkyripdanssdssdtdt 114
EFC49640        624 ydeitknpnlfkYSD-DIYRELE--GEATKTdyypDPVnEDGwYlmkFGVGVDAGVASFFDLKYYNNMEAFGLpfkqksl 700
EFC48838        703 feascklsfnsdw-------qdyffkkmeqdnypsklaapFGIITSSGYGDGCYACLFKKSKGGDVIAVRL 766
WP_007070895    163 egniyddffadifaksyeaaprfqreggdwinftipgtsyRLPMIQSGFGDGCYPVYFGYDRAGNLCRMVM 233 Dialister invisus
WP_083687607    163 dgrlysdyfgplfeqsrisspeiqneggsflnwtvpgtsyRIPMFQTGWGEGQYPVYWGQDEEGRVCQLVV 233 Negativibacillus mass...
WP_004327342    164 ddnpydgyfaalfkenyylhpeyqraggdwlnwqvpgteyHIPIFQSGFGDGTYPVYWGIDEGGEICQLVI 234 Bacteroidales
jgi:Weevi_1721  168 danlyddyfeplfkenlknhpnyqsedgdwinwsvpesdaKFPIFQAGFGEGVYPVYYGYNEKNEIIALYI 238
CBK97746        160 didpyndlfcdlleenakaypkyqgdcgdwlnwtvpgtdcNLPIFASGWGDGYYPVYFGYDAKGKICAVYV 230
CDC25310        160 didpyndlfcdlleenakeypkyqreygdwlnwnipgtdyHLPIFASGWGDGAYPCYFGYDADGKVCGVYI 230
Q5R0R9          308 sleg-------------------------ktellsmtgqdDCVICTSGFGDGAYPAFWGVNEQDEVVSLYI 353 Idiomarina loihiensis
jgi:GYMC10_1075 115 dw--------------------yyaccditesgeeagvldGGVVSRTGIGDGAYGVYKAVNEQDQVVGVKI 165
EFC49640        701 lekafklsygsew-------snylskemqklhypskmaapYGIITSSGYGDGCYACLFKKSEAGDVIAVRM 764
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