1CB5_B 4 GLNSEKVAALIQKLNSDPQFVLAQNVGTTHDLLDICLKR-ATVQRAQHVFQHAVPQEgkPITNQKSSGRCWIFSCLNVMR 82 human Q1G8V8 4 EISFDTIEDFTSNLSKHPAYGVAANAAQTNGIFKASQST-QSKVDLDPTFSVEIDTG--SVTNQKQSGRCWMFSALNTMR 80 Lactobacillus delbrue... Q5FM39 4 EISKDTINKFEQDLTNHPAYKVASRAAQENGIFKASQDL-QTKIDLDPTFSIEIETG--KPADQKQSGRCWMFSALNTMR 80 Lactobacillus acidoph... Q5M650 3 sLSTDFTEKLFADYKANAKYGAIENAVTHNGLLKSIETR-QSEVENDFVFSIDLTKD--EVSNQKASGRCWMFAALNTFR 79 Streptococcus thermop... Q9CEG3 2 tVTSDFTQKLYENFAENTKLRAVENAVTKNGLLSSLEVR-GSHAANLPEFSIDLTKD--PVTNQKQSGRCWMFAALNTFR 78 Lactococcus lactis su... O69192 4 ELTFEQLENFSRKWRENPDKLVFQASIMKNGIKAATENP-TSKVSIQPVFSHEVATD--KVSNQQQSGRCWMFAALNTFR 80 Listeria monocytogene... Q1GBV7 4 ELSPQLLESFSRDFNADPKNQVISRAARRSGLLEAAYNP-AVSHRLNRTFSIELDTD--NVTNQQQSGRCWLFSTLNVVR 80 Lactobacillus delbrue... Q1GBV8 4 ELTLQELAEFSANFNADPKNQVIARAAARSGVLEASYNE-RVAGRLTRVFSTELPTD--NVTNQKQSGRCWLFSTLNVLR 80 Lactobacillus delbrue... Q5FMH5 4 ELTVQELEKFSADFNKNPKNKIIARAAQRSGVLEASYND-RVEGELTRVFSTELDTD--NVTNQLHSGRCWEFSTLNVLR 80 Lactobacillus acidoph... O83150 2 YLTKELLDTFAHEVAADPIHKAVAGAVARVGLEEAALNT-EVARQHTHIFSTETKRG--EMTNQKMSGRCWIFAALNAAR 78 Treponema pallidum 1A6R_A 21 SIDISKINSWNKEFQSDLTHQLATTVLKNYNADDALLNKtRLQKQDNRVFNTVVSTDstPVTNQKSSGRAWLFAATNQLR 100 baker's yeast Q9W3F6 39 VITNQLLEKWRKNFYSEPKNLLAQNVCSRVDPFDVCLSR-KALETTNHVFNYKVETEgkPVTNQRSSGRCWLFAALNCIR 117 fruit fly P87362 5 GLSTEKAAAFTRRLRAEPQFLLAQNVATCSDPLEVCLQR-QVVQDTIQVFQHAVPAEgkPVTNQKNSGRCWIFSCLNAMR 83 chicken
1CB5_B 83 LPFMKKLNIEEFEFSQSYLFFWDKVERCYFFLSAFVDTAqrKEPEDGRLVQFLLMNPANDGGQWDMLVNIVEKYGVIPKK 162 human Q1G8V8 81 HSIQKEFKLKGFELSQSYTFFWDKFEKSNFFFENVIGSA--DKPLGDRKVSFLFATPQSDGGQWDMLCGLIEKYGIVPKK 158 Lactobacillus delbrue... Q5FM39 81 HPLQKKFQLKDFELSQNYTNFWDKFEKSNWFFENVIATA--DKPLGDRKVSFLFATPQQDGGQWDMLCGIIEKYGIVPKS 158 Lactobacillus acidoph... Q5M650 80 HKLISDFKLESFELSQAHTFFWDKYEKSNWFLEQIIATA--DQEIGSRKVKFLLDTPQQDGGQWDMVVSLFEKYGVVPKS 157 Streptococcus thermop... Q9CEG3 79 HKFINEFKTEDFEFSQAYTFFWDKYEKSNWFMEQIIG----DIEMDDRRLKFLLQTPQQDGGQWDMMVAIFEKYGIVPKA 154 Lactococcus lactis su... O69192 81 HKLNGTLGLKDFELSQNYTNFWDKLEKANYFLENIIETA--SEDEDSRLVSWLLDTPQQDGGQWDMLVSIIEKYGVVPKS 158 Listeria monocytogene... Q1GBV7 81 HNFGKANKAKNFTFSQSYNFFWDKIERANYFYDRIIATA--DRPLTDRTVRGYFDWCQTDGGQWHMAASLIAKYGVVPAY 158 Lactobacillus delbrue... Q1GBV8 81 HDFGAKHKAKNFTLSQSYNFFWDKLERANLFYEKVIETA--DKPLDDREVRSYFDFAGHDGGQWHMAVSLVKKYGVVPSY 158 Lactobacillus delbrue... Q5FMH5 81 HAFGKKYKAKNFTFSQAYNFFWDKIERANMFYNRILDSA--DMPLDSRQVKADLDFAGADGGQFQMAAALVEKYGVVPSY 158 Lactobacillus acidoph... O83150 79 VNTMKKLDIETVEFSQNYLFFWDKLEKANFFLENILETL--DEPLTSRLMAHLLANPVQDGGQWDMFSGLLEKYGLVPKE 156 Treponema pallidum 1A6R_A 101 LNVLSELNLKEFELSQAYLFFYDKLEKANYFLDQIVSSA--DQDIDSRLVQYLLAAPTEDGGQYSMFLNLVKKYGLIPKD 178 baker's yeast Q9W3F6 118 LPFMKNYNLDEFEFSQAFLFYWDKIERCNYFLNNVVKTAqrGEKVDGRLVSFLLLDPTSDGGQWDMLVNLITKHGLMPKK 197 fruit fly P87362 84 LPFMKKYNIEEFEFSQSYLFFWDKVERCYYFLNAFVETAqkKEPIDGRLVQFLLTNPTNDGGQWDMLVNIVEKYGVVPKK 163 chicken
1CB5_B 163 CFPES-YTTEATRRMNDILNHKMREFCIRLR-NLVHSGATKGEISATQDVMMEEIFRVVCICLGNPP----ETFTWEYRD 236 human Q1G8V8 159 VYPET-ANSENSRALDDTLNTMLRKGGLELR-ALVNEGKSAEEVEAHKAELLDAIFRMLATSLGLPP----KSFNFEYTD 232 Lactobacillus delbrue... Q5FM39 159 VYPET-ANATNSSALNDTLNTLLRKDGLELR-KLVNDGKSEEEIQTRKEEMLNDVFRVLAVSLGVPP----KKFNFEYRD 232 Lactobacillus acidoph... Q5M650 158 VYPES-VASSNSRELNQYLNKLLRQDAQILR-DLIASGADQAAVQAKKEEFLQEIFNYLAMTLGLPP----RQFDFAYRD 231 Streptococcus thermop... Q9CEG3 155 VYPES-QASSSSRELNQYLNKLLRQDAEILR-YTIEQGGD---VEAVKEELLQEVFNFLAVTLGLPP----QNFEFAFRN 225 Lactococcus lactis su... O69192 159 AMPET-FQSGKSADLNHLLNERLRTDAVILR-KAFTEKKD---TAGLKEEMLAEIYQLLVMTLGEPP----KVFDFEYRN 229 Listeria monocytogene... Q1GBV7 159 SMPES-FNSNHSQALDMVLADKERKDALTLR-RLAQAGDQ-EKLEAARTDFLSQIYRIMATALGEPP----KTFDLEFRD 231 Lactobacillus delbrue... Q1GBV8 159 VMPES-FNTSATNGLASALADKERKDALALR-RLAQAGDQ-EGLEKARKTFLNEIYRMVAIAVGEPP----KTFDLEYRD 231 Lactobacillus delbrue... Q5FMH5 159 AMPET-FNTNNTTSFATALGDKLKKDALVLR-ELKQYGKD-DEIAKTREKFLSEVYQMTAIAVGEPP----KTFDLEYRD 231 Lactobacillus acidoph... O83150 157 CMPET-FHSSNSRVLLAVLTRRLRKHAQLLR-SAHEEGVALHTLREKKEAFLSSIYSILVKALGRPP----EKFDFVYKD 230 Treponema pallidum 1A6R_A 179 LYGDLpYSTTASRKWNSLLTTKLREFAETLRtALKERSADDSIIVTLREQMQREIFRLMSLFMDIPPvqpnEQFTWEYVD 258 baker's yeast Q9W3F6 198 CFPES-FSCESSLRMNAILKSKLREYARNLR-VLMEKNPTDEEIACKIQEQMAEIYKVVGICLGIPS----ETFTWEYYD 271 fruit fly P87362 164 YFPES-HTTEATRRMNEILNHKMREYCLRLR-NMVATGTNKEELCAAMDTMIEEVFRIVSTCLGNPP----ETFCWEFRD 237 chicken
1CB5_B 237 KDKNYQKIGPITPLEFYREHVKplFNMEDKICLVNDPRPQHKHNKLYTVEYLSNMVGGRKTLYNNQPIDFLKKMVAASIK 316 human Q1G8V8 233 DDGNYHIDKDITPQDFFKKYVG--WDLENYISVINGPTADKPYNKVFSVEYLGNVVGGRQVRHLNLELSKFKDLIINQLK 310 Lactobacillus delbrue... Q5FM39 233 DDKNYHIDKDITPKEFFDKYVG--MDLEDHISTINAPTSDKPFHKVFSVEYLGNVEGGRQVRHLNLKVDEMKDLIIKQLK 310 Lactobacillus acidoph... Q5M650 232 KDDNYQSEKGITPRAFFEKYVG--LKLSDYVSVINAPTADKPYGKSYTVEMLGNVVGAPSVRYINLPMDRFKELAIAQMK 309 Streptococcus thermop... Q9CEG3 226 KDNEYKKFVG-SPKEFYNEYVG--IDLNNYVSVINAPTADKPYNKSYTVEFLGNVVGGKEVKHLNVEMDRFKKLAIAQMQ 302 Lactococcus lactis su... O69192 230 KDNEFKQELQITPKDFYERYVD--MDLKNYIPLINAPTKDKPFNQAFTVDYLGNIVNGTPIKYLNVEMDVLKKAATDQIK 307 Listeria monocytogene... Q1GBV7 232 DDKNYHLDKGLTPVQFYKKYCA--TDLDDYVVLANAP--DHEMNRVLHLGFEDNIKGGYPNLFINVPMEYLEDAAIAQLK 307 Lactobacillus delbrue... Q1GBV8 232 DDKNYHLEKNLTPVSFFNKYFD--VDLDDYVVLTNAP--DHEYGKLYHLGAEDNVEGGSPILFLNVPMEYLEQAAVAQLK 307 Lactobacillus delbrue... Q5FMH5 232 DDKKYHLDKNLTPLEFLHKYMGe-VDFDDYVVLTNAP--DHEYNKLYGLPAEDNIEGSLRIKLLNVPMEYLSSAAIAQLK 308 Lactobacillus acidoph... O83150 231 KEKKFHKVRDLTPQKFFCDFVG--WDLKNKVSLIHAPTADKPFGRAYTVKFLGTVKEAPCICYVNTPIEVLKEATASAIR 308 Treponema pallidum 1A6R_A 259 KDKKIHTIKS-TPLEFASKYAK--LDPSTPVSLINDP--RHPYGKLIKIDRLGNVLGGDAVIYLNVDNETLSKLVVKRLQ 333 baker's yeast Q9W3F6 272 KSKNYQSIGPVSSLEFYERYVKphFNVEDKVCLVTDPRPTSSYDQAYTVDCLGNVVGGRPVLYNNQSVELLLAVVTKSLK 351 fruit fly P87362 238 KEKNYHKFGPMTPVQFYNEHVKpyFNMEDKVCLVNDPRPQNPYCQLYTVEYLGNMAGGRKTLYNNQPIEVLKKLAATSIK 317 chicken
1CB5_B 317 DGEAVWFGCDVGKHFNSKLGLSDMNLYDHELVFGVSLKNm-NKAERLTFGESLMTHAMTFTAVSEkDDqdGAFTKWRVEN 395 human Q1G8V8 311 QGEVVWFGSDVSKGGDREAGLLDTKIYQRDQLFDYDFSM--SKADRLDSGESMMNHAMVITAVDL-VD--DKPTKWKIEN 385 Lactobacillus delbrue... Q5FM39 311 SGEVVWFGSNVVKDSERRAGLLDTDLYRRDELFDVDFSM--SKAEKLDSGESMMDHAMVITGVDI-VD--GKPTKWKIEN 385 Lactobacillus acidoph... Q5M650 310 AGESVWFGSDVGQVSDRQKGILATNVYDFTASMDINWTQ--DKAGRLDYSESLMTHAMVLTGVDLdAD--GKPIKWKIEN 385 Streptococcus thermop... Q9CEG3 303 AGETVWFGCDVGQESNRSAGLLTMDSYDFKSSLDIEFTQ--SKAGRLDYGESLMTHAMVLAGVDLdAD--GNSTKWKVEN 378 Lactococcus lactis su... O69192 308 DGETVWFGCDVGQLSEKTTGIMDTDIFLLNQTFGFKTAM--TKAERLDYKHSMLTHAMVLTGVNV-AN--GEVNRWKVEN 382 Listeria monocytogene... Q1GBV7 308 DGEAVWFGNDVGRQMDRKTGFMDLDLYQLDQLLDIDSHL--SKADRLATGIGESSHDMALVGVDV-DG--GQVRQWKVEN 382 Lactobacillus delbrue... Q1GBV8 308 DGEAVWFGNDVGRQMDHKTGYLDTDLYKLEDLFAVDLSL--SKADRLATGVGEVSHAMTLVGVDE-DK--GDIRQWKVEN 382 Lactobacillus delbrue... Q5FMH5 309 DGEAVWFGNDVLRQMDRKTGYLDTNLYKLDDLFGVDLKM--SKADRLRTGVGEVSHAMTLVGVDE-DN--GEIRQWKVEN 383 Lactobacillus acidoph... O83150 309 AGEPVWFGCDVGQMMTRKDGIMDTEIFGYESMLGTTPEF--NKAERLDYGESLLTHAMVITGFDEdAQ--GNPVRWQVEN 384 Treponema pallidum 1A6R_A 334 NNKAVFFGSHTPKFMDKKTGVMDIELWNYP-AIGYNLPQ--QKASRIRYHESLMTHAMLITGCHVdETs-KLPLRYRVEN 409 baker's yeast Q9W3F6 352 AGEAVWFGCEVSKRFASKQGIEDVDVHDFKLVFDIDIQTtfSKADRLIYGESAMTHAMVFTAVSVdKS--GVAQKLRVEN 429 fruit fly P87362 318 DGEAVWFGCDVAKHFYSKLGINDLNIFNHELVFGVSVKNm-NKAERLIFGDSLMTHAMVLTAVSEkDGqeDCYEKWRVEN 396 chicken
1CB5_B 396 SWGEDHGHKGYLCMTDEWFSEYVYEVVVDRKHVPEEVLAVLEQ---EPIILPAWDPMG 450 human Q1G8V8 386 SWGDKPGFKGYFVMSDEWFDQFVYQAVLNKAFLPEDVKKAYDEgkeNPIELLPWDPMG 443 Lactobacillus delbrueckii subsp. bulgaricus... Q5FM39 386 SWGEKPGFKGYFVMSDKWFDSFVYQAVINKKFLPDDLKKAYDEgvkDPIQLLPWDPMG 443 Lactobacillus acidophilus Q5M650 386 SWGDKVGQKGYFVASDAWMDEYTYQIVVRKDFLTAEELAAYEA---DPQVLAPWDPMG 440 Streptococcus thermophilus LMG 18311 Q9CEG3 379 SWGKDAGQKGYFVASDEWMDEYTYQIVVRKDLLTEEELAAYEE---KPQVLLPWDPMG 433 Lactococcus lactis subsp. lactis Il1403 O69192 383 SWGEKIGNNGYFVASDAWMDEFTFQVVVHKKYLSKELIEAFNQ---EPIALKPWDPMG 437 Listeria monocytogenes EGD-e Q1GBV7 383 SWGDKSGEKGYFTMSADWFREYTYEVAVQKKHVPAEILDLLKN---QPIELDPWDSLi 437 Lactobacillus delbrueckii subsp. bulgaricus... Q1GBV8 383 SWGDKSGEKGFFVMSHNWFKEYVYEVVVHKKYLTKDQQELLSS---TPVELAPWDSLA 437 Lactobacillus delbrueckii subsp. bulgaricus... Q5FMH5 384 SWGEKSGSKGFFVMSNDWFNDYVYEVVVHKKYLTDKQKELAEG---PITDLPAWDSLA 438 Lactobacillus acidophilus O83150 385 SWGDDTGKKGMFSMSDRWFDEYLYQITIDKKFVPQVWLDALEK---PIIALEPWDPMG 439 Treponema pallidum 1A6R_A 410 SWGKDSGKDGLYVMTQKYFEEYCFQIVVDINELPKELASKFTSgkeEPIVLPIWDPMG 467 baker's yeast Q9W3F6 430 SWGEDRGEKGYLVMNADWFREFGFEVVVDKKYVPEDVLRVFDM---DPIVLPAWDPMG 484 fruit fly P87362 397 SWGEDRGNKGYLIMTDDWFSEYVYEVVVDKKYVPEDVLAVMEQ---EPIVLPAWDPMG 451 chicken
Jiyao W et al.(2023). "The conserved domain database in 2023.",