1TO6


Conserved Protein Domain Family
TIGR00045

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TIGR00045: TIGR00045 
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glycerate kinase
The only characterized member of this family so far is the glycerate kinase GlxK (EC 2.7.1.31) of E. coli. This enzyme acts after glyoxylate carboligase and 2-hydroxy-3-oxopropionate reductase (tartronate semialdehyde reductase) in the conversion of glyoxylate to 3-phosphoglycerate (the D-glycerate pathway) as a part of allantoin degradation. [Energy metabolism, Other]
Statistics
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PSSM-Id: 272872
Aligned: 13 rows
Threshold Bit Score: 453.285
Created: 7-Oct-2014
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1TO6_A         2 KIVIAPDSFKESLTAQQVAEAIKRGFQQSIAD-VECLLCPVGDGGEGTVDAIRHSLDLEEKCLQVTGSFGQK-EVMRY-- 77  Neisseria menin...
CAB39872      10 RVVVAPSGFKESLSARAAADAIAAGVRRVLPD-AEIDRIPLVDGGEGTAVALASATGGRLVALAATGPVGDR-VGTHFal 87  Streptomyces co...
P57099         2 KIVIAPDSFKESLTAQQVAEAIKRGFQQSIAD-VECLLCPVGDGGEGTVDAIRHSLDLEEKCLQVTGPFGQK-EVMRY-- 77  Neisseria menin...
P73408         3 QILIAPDSFKGTLSAGEVCQIALD---VLAPE-FDCVAHPLADGGEGTLEAIANNLDGQWQTVRVQGPLPDQtVDACYlw 78  Synechocystis s...
P77364         2 KIVIAPDSFKESLSAEKCCQAIKAGFSTLFPD-ANYICLPIADGGEGTVDAMVAATGGNIVTLEVCGPMGEK-VNAFYgl 79  Escherichia col...
Q9Z9P2         3 TIVIAPDSFKESMTALQAARAIEKGFRRVIPN-ANYRLIPMADGGEGTVQSIVDALQGERKVVKVEGPLGDT-VEAEYgl 80  Bacillus halodu...
WP_029657931  10 KIVIAPDSFKESMTAQQVGNIIKQAFTNVYGNtLHYDIIPMADGGEGTTDALMHATGATKYTVIVNDPLMRP-IEACYar 88  Staphylococcus ...
WP_000312713  29 KIVIAPDSYKESLSASEVAQAIEKGFREIFPD-AQYVSVPVADGGEGTVEAMIAATQGAERHAWVTGPLGEK-VNASWgi 106 Escherichia coli
WP_002387160  11 KFVLAPDSFKESMSAKEACLAMEKGILAVFKD-ADIQHVPMADGGEGTVDSLVDATGGTRVPVRVAGPLPDQiVETYYgl 89  Enterococcus fa...
WP_010990054   2 KIVIAPDSFKESATAVEVATAIKKGWTKARPA-DQISLAPVSDGGEGFLTVLSESSEVELFQAEVTNLNGHK-IMASYgi 79  Listeria monocy...
WP_010956426   3 KIVIAIDSFKGCLSSVEAGEAAAEGVRAACPI-AEVMVLPVADGGEGMQDVLIAATDGQRIAVRAHSPLMEM-REASYgi 80  Porphyromonas g...
AAL61903       2 KIVISPDSFKECLPAWKVAEALATGWRKVLPG-SQLVCLPVADGGEGTLETLIHATDGTFYTKKVTGPLGES-IHAQYgi 79  Escherichia coli
WP_003082051   2 KIVIAPDSFKESLSAPDVAEAIARGWRRVFPQ-AEVLLRPLADGGEGTVDAVLAATAGERRECRVEGPLGEP-TLAHWgw 79  Pseudomonas
1TO6_A        78 FQKEQLALFEVADLVGLGKIPLEKRNPLQIQTRGIGELIRHLISQEIKEIYIGVGGTASNDGGIGIAAGLGYQFYDEDGN 157 Neisseria menin...
CAB39872      88 LGTGDTAVVEMAAVAGLSLVPRALRDPGATTTYGVGELIRAALGTGVRRVLVGCGDSGTSDGGAGALQALGARLLDGDGF 167 Streptomyces co...
P57099        78 FQKEQLALFEVADLVGLGKIPLEKRNPLQIQTRGIGELIRHLISQEIKEIYIGVGGTASNDGGIGIAAGLGYQFYDEDGN 157 Neisseria menin...
P73408        79 LPQEETAVIEMARASGLPLVPVGEHNPEIATSYGTGELITHAARRGAKQIQLAIGGSATNDAGLGLLMALGWQFLDSQGQ 158 Synechocystis s...
P77364        80 TGDGKTAVIEMAAASGLMLVAPEKRNPLLASSFGTGELIRHALDNDIRHIILGIGGSATVDGGMGMAQALGVRFLDADGQ 159 Escherichia col...
Q9Z9P2        81 SGDRKIAVIEMAQASGLHLVPKEKRNPLWTSTYGTGQLLIDALDEGVEQIILGIGGSATNDGGAGMAQAVGVRLLKENGE 160 Bacillus halodu...
WP_029657931  89 ADEQQIAIIEMAAASGLDLLEKEERNPLYTSSYGTGELIKDALNHGAKTIILGIGGSATNDGGTGMLSALGVKFTDVNGD 168 Staphylococcus ...
WP_000312713 107 SGDGKTAFIEMAAASGLELVPAEKRDPLVTTSRGTGELILQALESGATNIIIGIGGSATNDGGAGMVQALGAKLCDANGN 186 Escherichia coli
WP_002387160  90 LGDQETVVIEMAKANGIELVKAAERNPLITSTYGTGEMIQHALNHGAKKIIIGIGGSVTNDGGAGMIQALGARLLDKEGQ 169 Enterococcus fa...
WP_010990054  80 HARQETAIIESANTIGLDLIPAADRNPAHASSAGVGELILASLDHNVKKIIIGLGGSGTNDGGAGLIQALGVALLDKNKQ 159 Listeria monocy...
WP_010956426  81 SADGQTAFIEMASISGLPLVPEDRRNPMQTTTFGTGELIKDALDRGCRKFIVGIGGSATNDAGLGMLQALGFRFYDRDGR 160 Porphyromonas g...
AAL61903      80 LGNQTTAVIELAQASGLELVSPVQRSPLYTTSFGTGELILAALEHNIDTVILCLGGSATNDGGIGLMSALGASFTDAEGL 159 Escherichia coli
WP_003082051  80 LDD-ATAVIEMASASGLHLVPRDRRDATRSSSRGTGELIRAALDAGARKIILGLGGSATNDAGAGLLGALGVRFLAADGE 158 Pseudomonas
1TO6_A       158 ALPAC----GQSLLNLASVSTENRYKIPEDVHIRILADVVSPLCGHQGATYTFGKQKGLDSTMFEVVDQAIQDFYEKVSP 233 Neisseria menin...
CAB39872     168 ELGPG----GRELNRLVRVDPSGLDARLKDTELLVACNPYNVLCGERGVARVFGPQKGATPAQVEELSAGLENWARVLTR 243 Streptomyces co...
P57099       158 ALPVC----GQSLLNLASVSTENRYEIPEDVHIRILADVVSPLCGHQGATYTFGKQKGLDSTMFEAVDQAIQDFYEKVSP 233 Neisseria menin...
P73408       159 SVGWG----GQALGKVAEIIPPVLN---AFPQVTVLCDVTNPFYGANGAAQVYAPQKGADPAMVQRLDQGLRHFARVVRE 231 Synechocystis s...
P77364       160 ALAAN----GGNLARVASIEMDECDPRLANCHIEVACDVDNPLVGARGAAAVFGPQKGATPEMVEELEQGLQNYARVLQQ 235 Escherichia col...
Q9Z9P2       161 PIGKG----GGKLKELARIDMSKVDPRIQQVKLQVACDVDNPLVGEKGAAVVYGPQKGATRATIRELDEQLLHFANIIEE 236 Bacillus halodu...
WP_029657931 169 LLQMN----GANLAHIAQIDITNLDSRLKEVTFKVACDVSNPLLGENGATYIYGPQKGADAKMIPKLDFAMSHYHDKIKM 244 Staphylococcus ...
WP_000312713 187 EIGFG----GGSLNTLNDIDISGLDPRLKDCVIRVACDVTNPLVGDNGASRIFGPQKGASEAMIVELDNNLSHYAEVIKK 262 Escherichia coli
WP_002387160 170 ELTRG----GGALDKLAQIDLTQFDQRIFATEVLVASDVNNPLTGPTGASHVFGPQKGATEEMVAQLDKNLAHYAAIIKK 245 Enterococcus fa...
WP_010990054 160 PIPPG----GIHLQELAYIDASNLNPKLKNIQFQIACDVTNPLLGENGATFVFGAQKGASPDMLVKLENAMQNYGAKLDQ 235 Listeria monocy...
WP_010956426 161 DIGEGmalcGGLLSEVYRIDDSSAHPALADSLFTVACDVRNPFCGPEGAAFAFAPQKGADEEMVARLDDSMQHLAAVIHR 240 Porphyromonas g...
AAL61903     160 SVSVN----GMGLAAIHHIDLQHLDPRLKNVKFIAACDVTNPLTGDNGATRVFAQQKGASANDLEQLEQGMKNYARCIYR 235 Escherichia coli
WP_003082051 159 ELAPG----GAALAGLHSLDLGGLDPRLVDVAVEVAADVDNPLCGPRGASAVFGPQKGASAEQVAQLDAALAHFAKVVAA 234 Pseudomonas
1TO6_A       234 AT---LK----LKGAGAGGGIAgGLCAFAQASIVSGIDTCLDLIDFDKKVSDVDLVIVGEGRLDRQSLAGKAPIGVAKRT 306 Neisseria menin...
CAB39872     244 DLgvvGTdlrtGSGTGASGGLG-AGLAAVGARLLPRFDVLLGHLDLDARLARADLVLTAEGALDHQTPRGKVPAEVARRA 322 Streptomyces co...
P57099       234 AT---LK----LKGAGAGGGIAgGLCAFAQASIVSGIDTCLDLIDFDKKVSDVDLVIVGEGRLDRQSLAGKAPIGVAKRT 306 Neisseria menin...
P73408       232 FD---GFei-nFPRAGAAGGMGgGVAWALETKIESGFTAIAKLTQLEQAMAGCDLVITGEGCFDHQSPQGKVVGGVLELA 307 Synechocystis s...
P77364       236 QT---EInvcqMAGGGAAGGMGiAAAVFLNADIKPGIEIVLNAVNLAQAVQGAALVITGEGRIDSQTAGGKAPLGVASVA 312 Escherichia col...
Q9Z9P2       237 EL---GKevasIPGAGAAGGLGaGLIAFLDAKLIPGVELVLQATNFHELVKDADFVITGEGRIDQQTVYGKTPIGVAKAA 313 Bacillus halodu...
WP_029657931 245 CT---GKsvnqIPGSGAAGGMGaALLAFCETTLTKGIDVVFDITDFHQRIKDADLVITGEGRMDYQTIFGKTPVGVALAA 321 Staphylococcus ...
WP_000312713 263 AL---HVdvkdVPGAGAAGGMGaALMAFLGAELKSGIEIVTTALNLEEHIHDCTLVITGEGRIDSQSIHGKVPIGVANVA 339 Escherichia coli
WP_002387160 246 EI---GIdvemMPGAGAAGGLGaGLLAFTKAQLRPGIDIVVEVNQLEEKIKAADYVFTGEGGMDFQTKFGKAPYGVSRLA 322 Enterococcus fa...
WP_010990054 236 FS---SQkittKKGAGAAGGIAaGLMTFLNADLLSGSTLVMELSNMKDKMKDADIVIVGEGRMDKQSMMGKIPVQIAQEA 312 Listeria monocy...
WP_010956426 241 HT---GQdivhIPGAGAAGGMGgGLLAFLGAVLKPGIELLLDALHFSEKIREADLILTGEGKADRQTLMGKVPAGVLAEA 317 Porphyromonas g...
AAL61903     236 CC---GKdvdtIPGSGAAGGVGaALMAFLDARLQPGISLVLEAIQYTQHLKYAALAIVGEGKLDSQSLNGKAPVGAAKVA 312 Escherichia coli
WP_003082051 235 TL---GEdfsrVPGVGAAGGLGfAARAFLRARFRPGIELVAELAGLADALVGADLVLTGEGRLDAQSLHGKTPVGVARIA 311 Pseudomonas
1TO6_A       307 P-VGVPVVAICGSLVEDLPS--LPfeNIQAAFSILEKSEPLEDSL--KNASLYLEHTASNIGHLLNMP 369 Neisseria meningitidis sero...
CAB39872     323 KlSGRPVLALAGTLGEGAHD--VP--GVDACHGIMPAPMALADAL--LRASELLTDATERALRMVLLG 384 Streptomyces coelicolor A3(2)
P57099       307 P-VGVPVVAICGSLVEDLPS--LPfeNIQAAFSILEKSEPLEDSL--KNASLYLEHTASNIGHLLNMP 369 Neisseria meningitidis MC58
P73408       308 KkINKPAIIVAGQCQLSQTV--LP--NVLKIFSLVGPDMPLEKAL--QHPQTALKKRLVQVKQYLIQS 369 Synechocystis sp. PCC 6803 ...
P77364       313 KqFNVPVIGIAGVLGDGVEV--VHqyGIDAVFSILPRLAPLAEVL--ASGETNLFNSARNIACAIKIG 376 Escherichia coli K-12
Q9Z9P2       314 KqYGVPVIAIAGSLGQGYEA--VFehGIDAAFSLVPRIMSLDEAM--QQGDSLLEQAARNIAVVSSWN 377 Bacillus halodurans C-125
WP_029657931 322 KqYHIPVIAICGSLGENYQH--VYdfGIDSAYSIISSPSTLEDVL--QNSEQNLLNTATDIARILKLQ 385 Staphylococcus aureus
WP_000312713 340 KkYHKPVIGIAGSLTDDVGV--VHqhGIDAVFSVLTSIGTLDEAF--RGAYDNICRASRNIAATLAIG 403 Escherichia coli
WP_002387160 323 KkYQKPVFACAGYIGKDVDV--LYeeGMTAIFGILAKAEPLEAAL--KNGPVNLERTVENIARTLQLV 386 Enterococcus faecium
WP_010990054 313 KkQGCFVLAIVGSLALENNL--AQqhGIDAFFPNIPEITDLPTLF--ENTTKNLERTAENIAKLTLIG 376 Listeria monocytogenes
WP_010956426 318 MkQEIPVVLLAGSIEDAVAL--NRa-GFLGLFPITPSPVSLREAMnpAYARDNLRRTAEQVCRLYafa 382 Porphyromonas gingivalis
AAL61903     313 QmMGVPVIAIAGYIDDQLDLneLRqcGIEACFSVVNGPCNLPTAL--SQGENNLIRLGENLAGYFRAI 378 Escherichia coli
WP_003082051 312 RqAGVPVVALAGSLGDGYQR--LHdaGIDAAFSLAPGPISLEQAC--AGAAAELEARAEQIARLWRLA 375 Pseudomonas
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