Conserved Protein Domain Family
BofA

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pfam07441: BofA 
SigmaK-factor processing regulatory protein BofA
This family contains the sigmaK-factor processing regulatory protein BofA (Bypass-of-forespore protein A) (approximately 80 residues long). During sporulation in Bacillus subtilis, transcription is controlled in the developing sporangium by a cascade of sporulation-specific transcription factors (sigma factors). Following engulfment, processing of sigmaK is inhibited by BofA. It has been suggested that this effect is exerted by alteration of the level of the SpoIVFA protein.
Statistics
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PSSM-Id: 462165
Aligned: 123 rows
Threshold Bit Score: 28.5652
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
CDA50869      10 IVLAVIFIIFKIFNLSIKIFFKLLINALIGAALLFVFNFVfAGLMNLSffyINITWLTALITGIFGVPGVVVLLIIG 86 
CCY92751       9 lGIFGFIIIISMF-RTKKFLLSLFMTALQGIASLIAANFI-GGFFGVH---LSVNAFSLGVCGLGGLPGTVMLLITD 80 
CDA89070       8 AVCVVLLIPIITMFKKGSFLKCIFLSAFQGLAALLAVNSL-GLLTGVS---LAVNWYTILACVCLGIPASISMLVLN 80 
CDC12874       8 LAVICAASVLWWMIKSEKGASCFAVSALQGLAAVFAVNLA-GLVTGIT---LAVNWYTLGTAVLLGLPGVITALGLN 80 
WP_022264812  11 VGVFLALVAIRKIMKSKHPIRSTLLGLLLGPACMLVINII-SIFTSVS---IPISPLSLGISSTLGIPGVTAMLLLQ 83  Pseudoruminococcus...
CDB23373      11 GIIFLLLFSVQIIIKAKNPLKKTFFSMLKGVATLAAVNAL-GAFTGVT---LPVSLLSLAIAAVIGMPGVTAMLIFN 83 
CDC02923      11 FGAFLLFAFAHYISKSRHPFKRSLLSMAIGLLTLLAVNLT-GSFTGVY---LPVSLVSVCCAAFGGVPGVTLMLGLN 83 
CDC82604      11 VSTVIFFAVIYAAKQSKKPLKRACGTVLTGLAALAAVNIS-GIFTGVY---IPVSCLSVCASAVGGIPAVTAMLIID 83 
CDF13963      30 VIILIILAILHKLGKNKKPLLRAFGSMIIGLSALFLVNVT-SVITQVH---IPISMFTVGVSAGGGVPAVALLLFLN 102
WP_003531796  11 AGIFCALLVLHVAAGSKKPFRRALGSALNGLVALVLVNIT-GGFTGVT---LPVSLLSLGVSAGLGIPGVTMLLLLN 83  [Clostridium] inno...
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