3DGT


Conserved Protein Domain Family
GH16_Strep_laminarinase_like

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cd02182: GH16_Strep_laminarinase_like 
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Streptomyces laminarinase-like, member of glycosyl hydrolase family 16
Proteins similar to Streptomyces sioyaensis beta-1,3-glucanase (laminarinase) present in Actinomycetales as well as Peziomycotina. Laminarinases belong to glycosyl hydrolase family 16 and hydrolyze the glycosidic bond of the 1,3-beta-linked glucan, a major component of fungal and plant cell walls and the structural and storage polysaccharides (laminarin) of marine macro-algae. Members of the GH16 family have a conserved jelly roll fold with an active site channel.
Statistics
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PSSM-Id: 185691
Aligned: 22 rows
Threshold Bit Score: 317.719
Created: 28-Oct-2004
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
 
active sitecatalytic
Conserved site includes 14 residues -Click on image for an interactive view with Cn3D
Feature 1:active site [active site]
Evidence:

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                                                                                         
3DGT_A          8 GWSQVFLDDFDGaa----------gSSVNTANWQFDTGtsypg-gagnWGTGEVESMTSSTSNVSLdgnGDLLITPRRDa 76   Streptomyces ...
YP_871890      53 GWTTVFSDDFTGpa----------gSGVNTANWLYDTGtgypg-gapnWGTGEVETMTNSTANVYQdgnGHLVIKPIRNa 121  Acidothermus ...
YP_003115017  184 NWNLVWQDTFGGns----------gTAPSSANWIEDTGhnsag-gpadWGTGEVESASSSTANVSVdgnGHLNITALKDg 252  Catenulispora...
YP_001826276  758 GWTELLRDDFDGpa----------nSRPSPANWSHDLGtcypgcpaprWGTGEIETMTDSTDNVRLdgqGVLEIVPTRK- 826  Streptomyces ...
XP_366256     202 FKKIVFQDNFAKqk---------agALPDQAKWLIDLGtqypg-gaanWGTQEIQTYTNNPANLGIk-nGALTITPVRN- 269  Magnaporthe g...
YP_003201651   40 TWQTVFRDDFTGs------------GLPDPNKWILTQGtsypg-gpdaFGTGEIETMTNRPENVDVr-nGNLYITPQRDs 105  Nakamurella m...
YP_003117914   52 GWNQVFLDDFGGa-----------sGSGIDGQWKYDTGpg------ssFGTGEIETMTNSTSNVHLdggGNLDITAQGS- 113  Catenulispora...
ZP_04476310   176 AWTEVWRDDFDGts----------gTSPSGANWILRTGtrypg-gaakWGTGEVETMSASTANVSLdgtGKLNIRAVRDg 244  Streptosporan...
YP_003114818   59 GWNTVFSDNFAGga----------gTAPSSANWFYDIGt--------gYGTGEREQTTNSTNNVYLdgnGHLVLKALNN- 119  Catenulispora...
XP_959407      33 GYHVHLPKGFKKalfienfalyvpgSLPSTSKWAFDLGtsypg-gpegWGTGEVQTYTASTDNIVIttsGTLQITPVKDp 111  Neurospora cr...
Feature 1              #  # #                                  # # #                  # #  #      
3DGT_A         77 -SGNWTSGRIETTRTDFQPp-aGGKLRVEARLQMPNvtgdaaAGYWPAFWMLGapfrg-nyqnWPGVGELDIMENVQGLN 153  Streptomyces ...
YP_871890     122 -NGSWTSGRIETQRTDFAAp-pGGQLEIIASLQQPNpa--sgLGYWPAFWALGaaarpvgatnWPSIGELDIMEDVNARS 197  Acidothermus ...
YP_003115017  253 -AGNWTSGRIETQRSDFAAp-aGGMLEVTATIKQPNva--npAGYWPAFWALGngsrt-gsgtWPAIGETDIMENVNGHQ 327  Catenulispora...
YP_001826276  827 -DGKWSSGRITTVRSDFAPp-pGGVLRIEASIALPDvtgpaaAGYWPAFWTLGadlrd-gytgWPGVGELDVMESVNGRD 903  Streptomyces ...
XP_366256     270 -GNAWTSARIETKAGSDVQcppGGKLRVEASLKLAAsdpatqLGIWPAFWMLGqgfrt-drnsWPKVAEIDILEVSNGVG 347  Magnaporthe g...
YP_003201651  106 -AGRWTSARVESAASNYRPp-aGGVMHVESRLQLPNvtgseaLGYWPAFWMLGgpyrq-drwsWPAIGEFDIMENVQGLN 182  Nakamurella m...
YP_003117914  114 -GSNWTSGRVQTTSANVGAp-aGGKLEVTASIQQPTg----gLGYWPAFWMLGpg-------qWPENGEIDIMEDVNALS 180  Catenulispora...
ZP_04476310   245 -AGDWTSGRVETQRTDFAPq-pGERLRFTARLKQPDvp--daTGYWPGFRATGaayrg-dynnWPAVGETDIMTDVNGRS 319  Streptosporan...
YP_003114818  120 -GGTWTSGRIESTRDDFQAp-pGGELEMSASIQQPNpa--ngLGYWPAFWSLGapmr--agggWPQSGEIDMMEDVNGLN 193  Catenulispora...
XP_959407     112 vTGNWTSSRIETVAARDIVcppGQAIRIEAWIKLGDlpvskqLGIWPAFWMMSsayrg-nywnWPMVGEIDILENVNGAS 190  Neurospora cr...
Feature 1             # #                                                                         
3DGT_A        154 KTWATMHCGtspGGPCNEts-----gIGNSTACpnttcqsgFHTYTMEWDRSVSp-----EAIRFSVDGVTYQTVTan-q 222  Streptomyces ...
YP_871890     198 QVAQTLHCGvnpGGPCNEts-----gLGSGLVAcsgc-qtgYHTYAVIVDRRNTs----aEQLRFYVDGNLNYTINes-q 266  Acidothermus ...
YP_003115017  328 TTSSGLHCGtapNGPCNEss-----gRGSGLRTcagc-lsaYHTYAEVIDRTQSd-----EQIRFLVDGQVTWTVSes-q 395  Catenulispora...
YP_001826276  904 TVFGSMHCGvldGGPCREpv-----gLTSGPRAcpdc-reaFHTYAVEVDLSPGa-----REVRWYRDDRVHHRVRad-a 971  Streptomyces ...
XP_366256     348 TVFHTAHCGvinGGPCKEkt-----gLGGSGQFpr----gkFVKVAVTIDRSNKaggfqqEKLEWSVDGKVTHTLTgaev 418  Magnaporthe g...
YP_003201651  183 WTYNVLHCGvwaGGPCNEqeginngvNNAGAPCkvttcqagMHTYGLEWDDSGPv-----EQLRWYLDGELTFTVNanqv 257  Nakamurella m...
YP_003117914  181 EVAGTIHCGvdpGGPCNEgn-----gIGSGLRAcggc-qsgFHTYTMILDRTNTs----aESIAFYLDGSQYFSVNes-q 249  Catenulispora...
ZP_04476310   320 QLSNTLHCGtapDGACNEyg-----gRTSGLATcegc-qtgFHEYTQIIDRTRSd-----EEIRFYLDGVQTWVVRqs-q 387  Streptosporan...
YP_003114818  194 EASQTLHDSa--NSPGHPli-----aCPGAGSGcq----tgYHTYSVIIDRTNTs----aEQMQFLMDGVVESTITea-s 257  Catenulispora...
XP_959407     191 AAWQTIHCGktaPGPCNEyt-----gITNKAAHrw----sgFHRFSVDIDRTNPggswkeEQIVWRIDGKAVFTVKgsrv 261  Neurospora cr...
Feature 1                         # # #                                       
3DGT_A        223 mDAATWTNATNHGFFVILNVAMGGGFPGafgggp-------tgatePGHPMVVDYVQVTS 275  Streptomyces sioyaensis
YP_871890     267 mDPTTWQNAIDHGFFLIFDVAMGGGFPNgvcgctt-----ptaattSGAGMSIDWVAVYQ 321  Acidothermus cellulolyticus 11B
YP_003115017  396 vGVTTWQNAVDHGFFLILDLAVGGSWPNadcgcts-----ptaattSGGTLSVGPIAVYS 450  Catenulispora acidiphila DSM 44928
YP_001826276  972 mDAGTWERAVDHGVFLILNVAVGGKLPEadgata-------gpatePGHPMRVDRVRVAV 1024 Streptomyces griseus subsp. grise...
XP_366256     419 kDADAWENLARTPKMILLNVAIGGEFPDgkakiktp---taktvggEPSAMSVQYVAAFS 475  Magnaporthe grisea 70-15
YP_003201651  258 pAATWNSLADHAGYFIILNVAMGGAFPNklgggp-------nagtkPGVPMVVDYVEVKY 310  Nakamurella multipartita DSM 44233
YP_003117914  250 vGTSTWQQAYDHNLSIILDLAMGGAFPNgvcgctt-----ptgstaSGGTMRVDYVAAYT 304  Catenulispora acidiphila DSM 44928
ZP_04476310   388 vGVSAWRAAVHHGFYLRFDLAIGGSLPDaiagftt-----ptaattSGGVLSVDSVSVSR 442  Streptosporangium roseum DSM 43021
YP_003114818  258 vGTAAWQAAIDHGFFIIWDLAMGGNYPDgvsgttt-----ptaattSGASLSAAWVAVYE 312  Catenulispora acidiphila DSM 44928
XP_959407     262 dDEKAWTALTRTPKYILLNVAVGGSFPDvlanpslertpnnatvggEGSAMEVRYVAVFS 321  Neurospora crassa OR74A

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