1HP8


Conserved Protein Domain Family
MTCP1

?
pfam08991: MTCP1 
Click on image for an interactive view with Cn3D
Mature-T-Cell Proliferation I type
Members of this family adopt a coiled coil structure, with two antiparallel alpha-helices that are tightly strapped together by two disulfide bridges at each end. The protein sequence shows a cysteine motif, required for the stabilization of the coiled-coil-like structure. Additional inter-helix hydrophobic contacts impart stability to this scaffold. The precise function of this eukaryotic domain is, as yet, unknown. MTCP1 is found in mitochondria. Mature-T-Cell Proliferation) is the first gene unequivocally identified in the group of uncommon leukemias with a mature phenotype.
Statistics
?
PSSM-Id: 430360
Aligned: 42 rows
Threshold Bit Score: 49.9878
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
?
Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
1HP8_A          12 PCQKQACEIQKCLQaNSYMESKCQAVIQELRKCCAQYPK-------GRSVVCSGFE-KEEE 64 
XP_002529007     8 PCKKEACDIQACLSkNNFLPQRCLKVIENLQSCCEKCEYk--------STHCGSVSsLLKQ 60 
XP_002960434     7 PCNQHACDIQACLQrNHYVMESCRQVILNLQKCCDECENr--------SKHCAALSgLIAQ 59 
EDX08106         8 PCKPNACRIQACLTkNHYQEDKCLDVLEAMRQCCLKWHKe--------SLCCSGID-LEKT 59 
EDS35093         9 PCKVSACRIQTCLKeHKFDETRCYDVLEAMRQCCLKWHQv--------SLCCSGIK-LDRD 60 
ybcl:Ecym_2134 154 ACKAEACAIQACLKrHGYDEGRCVAAVNELYACCRRFYRgq---rgGSSSCCPGAE-VVER 210
G2TRJ8           3 DCQKEACNLQSCIQrNQYNQGNCEKFVNDLLLCCKRWYDknsltgnEAPHTCPELK-PLLR 62  Schizosaccharomyces pombe 972h-
XP_007416662     9 ICQLEACQLQKCLNrFTYQPERCEELVKRLYKCCKVMYDeng--dqIKSTACASKE-KVKE 66 
EDR07833         6 TCQTEACDLQSCLNrNTYAPEKCEKNLRSLYECCQRFYKlte--grGESTSCPLPN-VVQR 63 
EGO00835         8 ECQAEACALQTCLSsNTYSPENCGRQLRGLYLCCKQMYSese--gkKESSACPMSS-VVER 65 
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap