2NW7


Conserved Protein Domain Family
TDO2

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COG3483: TDO2 
Tryptophan 2,3-dioxygenase (vermilion) [Amino acid transport and metabolism]
Statistics
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PSSM-Id: 442706
Aligned: 139 rows
Threshold Bit Score: 240.475
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2NW7_A         5 KN----LRD-----L--EPGIHTD--L-EGRLTYGGYLRLDQLLSAQQPLS-------EpaHHDEMLFIIQHQTSELWLK 63 
WP_011521489 334 estapvearsssgcpvaHGNGAGD----EHKLTYGSYLKIPELLSLQQLQSe-----pP--RHDELLFIVIHQTYELWFK 402
WP_081453281   2 cptsrsHRPrclpfVevDEAVIVD--H-SPVLTYSSYLALDEILTAQRPHS-------D--EHEEMLFIVVHQVHELWFK 69 
WP_015202260   5 nknietalnelekrYgnRLVENLEsnVyRRELTYDDYLKIETLLSLQQPLT-------D--YHDELIFLVYHQQTELWFK 75 
WP_038503102   1 -------------------mgEKD----QKAITYISYLKVDELLELQQPESd------G--EHDEMLFIIIHQTYELWFK 49 
WP_070954934   1 -----------mvqietPDSHERN----QKHITYISYLKVDELLELQQPES-------N--EHDELLFIIIHQTYELWFK 56 
WP_091807311   2 pdtgntGRP-----DgtEQGGTHEv-P-HASLTYTSYLALDEVLGAQRPRS-------A--EHDELLFIVIHQVYELWFK 65 
WP_095671694   1 -------------------msDQD--F-DSALTYTSYLAVDELLKLQKPLSkstdsegP--EHDEMLFIIIHQSYELWFK 56 
WP_054048975   1 -------------------msSTD--T-QAALTYTSYLALDEVLGAQRPRS-------E--EHDELLFIVIHQVYELWFK 49 
WP_082859716  12 SEeirrRQA-----EqtGGGPQTE--FpTGNTPFVEYARMDELLQLRRPRT-------K--ALTEPAFIVMSQVKELLFD 75 
2NW7_A        64 LLAHELRAAIVHLQ--------RDEVWQCRKVLARSKQVLRQLTEQWSVL-ETLTPSEYMGFRDVLGPSSGFQSLQYRYI 134
WP_011521489 403 ELLHDLEAVVRCLQavardpraRDEVYEAARLLRRCTEVLRVLVSQFTIL-ETMLPTHFLAFRDKLEPASGFQSQQFRQI 481
WP_081453281  70 QLLHEFAGLQRQLA--------LGDSAHVLHSLRRSLGILKAVIAQIDVL-ETMTPSQFTSFRGNLGTASGFQSAQFREI 140
WP_015202260  76 LVIHELERAIKALKa------sTSDIISSIDAVTRINRYFAIITNSFSVLmEGLSTEEFLIFRKAFGSASGFQSLQFRII 149
WP_038503102  50 QMLHEIAELQRTLE--------AGQSHRSLAILGRVRTIMKTCVGQLDIL-ETMTPLQFNTFRGRLQSSSGFQSAQFREF 120
WP_070954934  57 QIIHELGALQQALE--------AGDTHRSQAILGRVRTIMKTCVAQVDIL-ETMTPLQFNSFRGRLSSSSGFQSAQFREV 127
WP_091807311  66 QLLHELGYLQVKLE--------EGDTPHSVRTLRRTLTILKVVVAQIDVL-ETMTPSQFTSFRARLEAASGFQSSQFREL 136
WP_095671694  57 QLIHEFEAAAKSLE--------AGDTHRSLAILGRIRTILKVCVTQVDIL-ETMTPLQFNAFRGYLSSSSGFQSAQFRKV 127
WP_054048975  50 QILHEVAELQRVLE--------SGHTPHAVRVLRRTLTIFKVIVAQIDVL-ETMTPRQFTSFRARLDASSGFQSAQFREL 120
WP_082859716  76 LLRTEFGTARGQLA--------KDAVEDALWTLRRASRIQDVLLASWDVL-AALTPLEFAEFRDVLGNASGFQSVSYRRL 146
2NW7_A       135 EFLLGNKNPQ-----------MLqvFAYDPAGQARLRE-VLEAPSLYEEFLR-YL-ARFGHAIP--QQy----------- 187
WP_011521489 482 EFLCGLRDEK-----------LMrvHEPEPKEHAELVK-RLHEPSLHDVLFD-AL-RALGKLPAyaPDa----------- 536
WP_081453281 141 EAVLGRRDRR-----------TFerYLEGSGERYRIES-AMNRPTLFDSFLG-YL-VVHGYPVP--HDl----------- 193
WP_015202260 150 EILAGLQRDVr-----------------EKPIQENAKYiETEQPQHQDKSEAkFYwECAARNLAt-NEptltllrfkeqh 211
WP_038503102 121 EAVLGRRDQAgagadkhsgmgMAehLIAGSPARARVEA-AMQRRSLWDSTLI-YL-ESRGHKMP--ADv----------- 184
WP_070954934 128 EAILGRRDHAgadaekstgmgMAehLIEGSTARARVEA-AMKRPSLWDSALR-YF-DSRGHKMP--ADv----------- 191
WP_091807311 137 EAVLGRRDRG-----------VFehYPAGSEARTRIAA-AMSRPSLFDSFVC-YL-REHGYDLR--RR------------ 188
WP_095671694 128 EALLGRRDSK-----------MAshLPI--DVQEEIHE-ITSRNSIWDSTLA-YL-SNRGHKIP--SDv----------- 178
WP_054048975 121 EAVLGRRDDH-----------AFahYPEGGEQRARIAA-AMSRPSLFDSFLA-YL-GTHGYKLP--AEv----------- 173
WP_082859716 147 EFLLGNKNPA-----------MAipHGKSP-AYHDIDA-QLREPSLYDEALG-LL-SRAGFDIP--DRc----------- 198
2NW7_A       188 -----------QARDWTAAH----VADD----TLRPVFERIYENTDRYWREYSLCEDLVDVETQFQLWRFRHMRTVMRVI 248
WP_011521489 537 -----------TDRDRFEARa--------------fAIRDVYEDEKHFRDWIDVCERLTEFDELVVSWRLRHIQMVERTI 591
WP_081453281 194 -----------LYRDVSLPL----EPSV----ELQSVLLQVYHDDD---VAAEVCEGLVDLDQRIQEWRYRHGKMVERII 251
WP_015202260 212 lpylnflysqrESLSLRLIFyqivSQRMkqeiEIVKLLETLFDEK-IEKDLIVLAEELLKMDEAIIHWKQAHLKTVAKHL 290
WP_038503102 185 -----------MNRDVTVGY----TDHE----GVQEVLLDVHRNDA---EAAMICEALVDLDEGLQEWRYRHVKMVERTI 242
WP_070954934 192 -----------LDRDVTVGY----SSDA----RVQQVLVSMHRSDL---EAASVAESLLDVDEGLQEWRYRHVKMVERTI 249
WP_091807311 189 -------------DDVSLPA----APSR----AVRDVLLRVYADDG---GPASVCEHLVDLDEGIQEWRYRHVKMVERTI 244
WP_095671694 179 -----------LERDKSTHY----QSDP----RVLEALLEVHRSDP---ESAMVCERLVDIDEGLQEWRYRHVKMVERTI 236
WP_054048975 174 -----------IGRDVAKPA----EPSR----AVQEVLLEVYADDS---GPSTVAEHLIDLDEGLQEWRYRHVKMVERTI 231
WP_082859716 199 -----------LRRDFAVPY----QPDD----AVESAWRAVYADPGGHRRLYLLAEGLMDTADQFARWRYTHLVTVQRML 259
2NW7_A       249 GF-KRGTGGSSGVGFLQQALAL-TFFPELFDVRTSV 282
WP_011521489 592 GL-KMGTGGSTGASYLRLTLDK-TFFPELWEARTML 625
WP_081453281 252 GD-KAGTGGSSGAAYLRATLST-PMFPDLWTVRGRL 285
WP_015202260 291 SQvRRGTGETNWGEYLTKSIAEhRCFPELQLAKQNV 326
WP_038503102 243 GH-KMGSGGSSGVGYLSSTLFR-PVFADLWAIRSRF 276
WP_070954934 250 GR-KPGTGGSPGVGYLASTLFR-PVFADLWEIRSQL 283
WP_091807311 245 GG-KEGTGGSSGAAYLRTTLSS-PVFPDLWSVRSEL 278
WP_095671694 237 GH-KVGTGGSDGVKYLASTLFN-PVFRDLWEIRSQF 270
WP_054048975 232 GS-KMGTGGSAGAAYLRSTLFA-PVFPDLWAVRSEL 265
WP_082859716 260 GA-KPGSGGTHGVAWLKGIAEH-RFFPELWSVRSTI 293
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