"KCCC/NGS Laboratory, Kuwait Cancer Control Center"[submitter] AND "RA - ClinVar

Warning: The NCBI web site requires JavaScript to function. more...

Search results

Items: 22

	Variation	Gene (Protein Change)	Type (Consequence)	Condition	Classification, Review status
Select item 2574680	NM_058216.3(RAD51C):c.37G>T (p.Asp13Tyr)	RAD51C (D13Y)	Single nucleotide variant (missense variant +1 more)	Breast-ovarian cancer, familial, susceptibility to, 3	GUncertain significance
Select item 232581	NM_058216.3(RAD51C):c.52C>T (p.Pro18Ser)	RAD51C (P18S)	Single nucleotide variant (missense variant +1 more)	Hereditary cancer-predisposing syndrome +3 more	GUncertain significance
Select item 492361	NM_058216.3(RAD51C):c.121G>A (p.Val41Met)	RAD51C (V41M)	Single nucleotide variant (missense variant +1 more)	not specified +4 more	GConflicting classifications of pathogenicity
Select item 2573179	NM_058216.3(RAD51C):c.145+1G>C	RAD51C	Single nucleotide variant (splice donor variant)	Breast-ovarian cancer, familial, susceptibility to, 3	GLikely pathogenic
Select item 138869	NM_058216.3(RAD51C):c.186A>G (p.Gln62=)	RAD51C	Single nucleotide variant (synonymous variant +1 more)	Breast-ovarian cancer, familial, susceptibility to, 3 +5 more	GBenign/Likely benign
Select item 136157	NM_058216.3(RAD51C):c.195A>G (p.Arg65=)	RAD51C	Single nucleotide variant (synonymous variant +1 more)	Fanconi anemia +7 more	GBenign/Likely benign
Select item 1730889	NM_058216.3(RAD51C):c.338G>T (p.Gly113Val)	RAD51C (G113V)	Single nucleotide variant (missense variant +1 more)	Breast-ovarian cancer, familial, susceptibility to, 3 +1 more	GUncertain significance
Select item 132721	NM_058216.3(RAD51C):c.376G>A (p.Ala126Thr)	RAD51C (A126T)	Single nucleotide variant (missense variant +1 more)	Breast and/or ovarian cancer +5 more	GBenign/Likely benign
Select item 128204	NM_058216.3(RAD51C):c.406A>T (p.Met136Leu)	RAD51C (M136L)	Single nucleotide variant (missense variant)	Hereditary breast ovarian cancer syndrome +5 more	GUncertain significance
Select item 142840	NM_058216.3(RAD51C):c.431T>C (p.Ile144Thr)	RAD51C (I144T)	Single nucleotide variant (missense variant)	Fanconi anemia complementation group O +5 more	GConflicting classifications of pathogenicity
Select item 471444	NM_058216.3(RAD51C):c.514C>T (p.Leu172Phe)	RAD51C (L172F)	Single nucleotide variant (missense variant)	Hereditary cancer-predisposing syndrome +2 more	GUncertain significance
Select item 2502442	NM_058216.3(RAD51C):c.561C>G (p.His187Gln)	RAD51C (H187Q)	Single nucleotide variant (missense variant)	Fanconi anemia complementation group O +1 more	GUncertain significance
Select item 138867	NM_058216.3(RAD51C):c.572-17G>T	RAD51C	Single nucleotide variant (intron variant)	Fanconi anemia complementation group O +5 more	GBenign/Likely benign
Select item 409842	NM_058216.3(RAD51C):c.634C>T (p.Arg212Cys)	LOC129390903, RAD51C (R212C)	Single nucleotide variant (missense variant +1 more)	Breast-ovarian cancer, familial, susceptibility to, 3 +3 more	GUncertain significance
Select item 484729	NM_058216.3(RAD51C):c.641G>A (p.Arg214His)	LOC129390903, RAD51C (R214H)	Single nucleotide variant (missense variant +1 more)	not provided +3 more	GConflicting classifications of pathogenicity
Select item 142154	NM_058216.3(RAD51C):c.706-18T>C	RAD51C	Single nucleotide variant (intron variant)	Fanconi anemia complementation group O +5 more	GBenign/Likely benign
Select item 2121546	NM_058216.3(RAD51C):c.710G>T (p.Arg237Leu)	RAD51C (R237L)	Single nucleotide variant (missense variant +1 more)	Fanconi anemia complementation group O +1 more	GUncertain significance
Select item 182827	NM_058216.3(RAD51C):c.730A>G (p.Ile244Val)	RAD51C (I244V)	Single nucleotide variant (missense variant +1 more)	Hereditary breast ovarian cancer syndrome +5 more	GUncertain significance
Select item 2505285	NM_058216.3(RAD51C):c.837+3A>T	RAD51C	Single nucleotide variant (intron variant)	Breast-ovarian cancer, familial, susceptibility to, 3	GUncertain significance
Select item 138868	NM_058216.3(RAD51C):c.837+13T>C	RAD51C	Single nucleotide variant (intron variant)	Fanconi anemia complementation group O +4 more	GBenign/Likely benign
Select item 1765149	NM_058216.3(RAD51C):c.892G>A (p.Val298Ile)	RAD51C (V298I)	Single nucleotide variant (missense variant +1 more)	Hereditary cancer-predisposing syndrome +2 more	GConflicting classifications of pathogenicity
Select item 128202	NM_058216.3(RAD51C):c.1102C>T (p.Arg368Trp)	RAD51C (R368W)	Single nucleotide variant (missense variant +1 more)	Breast-ovarian cancer, familial, susceptibility to, 3 +5 more	GConflicting classifications of pathogenicity

ClinVar

Result Filters

Classification type

Germline classification

Types of conflicts

Molecular consequence

Variation type

Variation size

Variant length

Review status

Additional filters

Search results

Items: 22