"Labcorp Genetics (formerly Invitae), Labcorp"[submitter] AND "LOC1067 - ClinVar

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Items: 73

	Variation	Gene (Protein Change)	Type (Consequence)	Condition	Classification, Review status
Select item 2170020	NC_000013.11:g.32315212G>A	BRCA2, LOC106721785 +1 more	Single nucleotide variant (intron variant)	Hereditary breast ovarian cancer syndrome	GBenign
Select item 1168940	NC_000013.11:g.32315300G>A	BRCA2, LOC106721785 +1 more	Single nucleotide variant (intron variant)	Hereditary breast ovarian cancer syndrome	GBenign
Select item 2174981	NC_000013.11:g.32315355A>G	LOC106721785, ZAR1L +1 more	Single nucleotide variant (5 prime UTR variant)	Hereditary breast ovarian cancer syndrome	GUncertain significance
Select item 2139291	NC_000013.11:g.32315397C>T	BRCA2, LOC106721785	Single nucleotide variant	Hereditary breast ovarian cancer syndrome	GUncertain significance
Select item 1166054	NM_000059.4(BRCA2):c.-296C>T	BRCA2, LOC106721785	Single nucleotide variant	not provided +3 more	GBenign/Likely benign
Select item 662866	NC_000013.11:g.(?_32315480)_(32315687_?)del	BRCA2, LOC106721785	Deletion	Hereditary breast ovarian cancer syndrome	GUncertain significance
Select item 660689	NC_000013.11:g.(?_32315480)_(32371120_?)del	BRCA2, LOC106721785 +1 more	Deletion	Hereditary breast ovarian cancer syndrome	GPathogenic
Select item 652952	NC_000013.11:g.(?_32315480)_(32319345_?)del	BRCA2, LOC106721785 +1 more	Deletion	Hereditary breast ovarian cancer syndrome	GPathogenic
Select item 584385	NC_000013.11:g.(?_32315480)_(32398790_?)del	BRCA2, LOC106721785 +3 more	Deletion	Hereditary breast ovarian cancer syndrome	GPathogenic
Select item 583428	NC_000013.11:g.(?_32315480)_(32316547_?)del	BRCA2, LOC106721785 +1 more	Deletion	Hereditary breast ovarian cancer syndrome	GPathogenic
Select item 882070	NC_000013.11:g.32315487G>T	BRCA2, LOC106721785	Single nucleotide variant (intron variant)	not provided +4 more	GConflicting classifications of pathogenicity
Select item 434531	NM_000059.4(BRCA2):c.-188C>T	BRCA2, LOC106721785	Single nucleotide variant (5 prime UTR variant)	Hereditary breast ovarian cancer syndrome +2 more	GConflicting classifications of pathogenicity
Select item 209599	NM_000059.4(BRCA2):c.-175C>T	BRCA2, LOC106721785	Single nucleotide variant (5 prime UTR variant)	Breast-ovarian cancer, familial, susceptibility to, 2	GBenign
Select item 264955	NM_000059.4(BRCA2):c.-162G>A	BRCA2, LOC106721785	Single nucleotide variant (5 prime UTR variant)	Breast-ovarian cancer, familial, susceptibility to, 2	GBenign
Select item 2761421	NM_000059.4(BRCA2):c.-143_-142insCGTCTTTTAGCATACAGGTCTTGTGCAGCTTTTATCAGATTTCTTCCTCTAAGTCTTGATACTTTTTTTTTTTTTAATAATACTTTAAGTTCCGCAATACATGTGCAGAACCTGCAGGTTTGTTACATAGGTATACACGTGCCATGGTGGTTTGCTACACCCATCAACCTGTCATCTACATTAGATATTTCTCCTAATGCTATCCCTTCCCTAGCCCCCCATCCCCCAATAGCCCCCGGTGTGTGATGTTCCCTGCCCTGTGTCCACGTGTTCTCATTGTTCAACTCCCACTTATCAGTGAGAACACGCGGTGTTTGTTTTTCTGTTCTCGTGTTATTTTTCTGAGAATGATATGGTTTCCAGCTTCATCCATGTCCCTGCAAAGGACATGAACTCATTCTTTTTTATGGCCACATAGTATTCTGTGGTGTATATGGGCCACATTTTCTTTATCCAGTCTATCATTGATGGGCATTTGGGTAGGTTCCAAGTCTTTGCTAATTTTGAAATTATCATTTCACAGCTTAATTTCTGATGGTTCCTTGCTAGTATTTAGAAATACAATTGATTTTTTTATGTTGATCTTAAAAAATTGCAAGCTTACCTATCTTGTTTATTAGATCTAGTAACTTATTTGTAGATTCCATTGGGTTTTCTACAAATAGACTCATGTTGCCTAAGAATAAAGGCTTACTTTTTTCCCACTATGAATCCTTTTTATTTGTATTTTTTTCCTTGCCTTATTGCACTGGCTAGAATCTAAAGTATAATGTTGAACAGACATGGTGAGAGCAGATATTCTTACAACTGACCCACACTTAGGTTTGTGGAGAAAGCACTCAGTCTTTCACCATTAAGTATGTTAACTGTACTTAGTTAACTGTAGGGC	BRCA2, LOC106721785	Insertion (5 prime UTR variant +1 more)	Hereditary breast ovarian cancer syndrome	GUncertain significance
Select item 2144940	NM_000059.4(BRCA2):c.-125G>C	BRCA2, LOC106721785	Single nucleotide variant (5 prime UTR variant)	Hereditary breast ovarian cancer syndrome	GUncertain significance
Select item 264878	NM_000059.4(BRCA2):c.-59_-57del	BRCA2, LOC106721785	Deletion (5 prime UTR variant)	Breast-ovarian cancer, familial, susceptibility to, 2	GBenign
Select item 2822681	NM_000059.4(BRCA2):c.-60A>T	BRCA2, LOC106721785	Single nucleotide variant (5 prime UTR variant +1 more)	Hereditary breast ovarian cancer syndrome	GUncertain significance
Select item 387446	NM_000059.4(BRCA2):c.-60A>G	BRCA2, LOC106721785	Single nucleotide variant (5 prime UTR variant)	Hereditary breast ovarian cancer syndrome +1 more	GConflicting classifications of pathogenicity
Select item 2865755	NM_000059.4(BRCA2):c.-59G>C	BRCA2, LOC106721785	Single nucleotide variant (5 prime UTR variant +1 more)	Hereditary breast ovarian cancer syndrome	GUncertain significance
Select item 1128272	NM_000059.4(BRCA2):c.-56_-55insCTC	BRCA2, LOC106721785	Insertion (5 prime UTR variant)	Hereditary breast ovarian cancer syndrome	GLikely benign
Select item 807001	NM_000059.4(BRCA2):c.-57A>G	BRCA2, LOC106721785	Single nucleotide variant (5 prime UTR variant)	not provided +1 more	GUncertain significance
Select item 719336	NM_000059.4(BRCA2):c.-56del	BRCA2, LOC106721785	Deletion (5 prime UTR variant)	Hereditary breast ovarian cancer syndrome	GLikely benign
Select item 506545	NM_000059.4(BRCA2):c.-56C>A	BRCA2, LOC106721785	Single nucleotide variant (5 prime UTR variant)	not specified +1 more	GConflicting classifications of pathogenicity
Select item 1154030	NM_000059.4(BRCA2):c.-55T>C	BRCA2, LOC106721785	Single nucleotide variant (5 prime UTR variant)	Hereditary breast ovarian cancer syndrome	GLikely benign
Select item 1400968	NM_000059.4(BRCA2):c.-54G>A	BRCA2, LOC106721785	Single nucleotide variant (5 prime UTR variant)	Hereditary breast ovarian cancer syndrome	GUncertain significance
Select item 1038113	NM_000059.4(BRCA2):c.-53C>T	BRCA2, LOC106721785	Single nucleotide variant (5 prime UTR variant)	Hereditary breast ovarian cancer syndrome	GUncertain significance
Select item 1981989	NM_000059.4(BRCA2):c.-52A>C	BRCA2, LOC106721785	Single nucleotide variant (5 prime UTR variant)	Hereditary breast ovarian cancer syndrome	GUncertain significance
Select item 209600	NM_000059.4(BRCA2):c.-52A>G	BRCA2, LOC106721785	Single nucleotide variant (5 prime UTR variant)	Breast-ovarian cancer, familial, susceptibility to, 2	GBenign
Select item 384062	NM_000059.4(BRCA2):c.-51C>T	LOC106721785, BRCA2	Single nucleotide variant (5 prime UTR variant)	not specified +1 more	GConflicting classifications of pathogenicity
Select item 1144050	NM_000059.4(BRCA2):c.-50C>A	BRCA2, LOC106721785	Single nucleotide variant (5 prime UTR variant)	Hereditary breast ovarian cancer syndrome	GLikely benign
Select item 2700378	NM_000059.4(BRCA2):c.-48C>T	BRCA2, LOC106721785	Single nucleotide variant (5 prime UTR variant +1 more)	Hereditary breast ovarian cancer syndrome	GUncertain significance
Select item 2113396	NM_000059.4(BRCA2):c.-48C>G	BRCA2, LOC106721785	Single nucleotide variant (5 prime UTR variant)	Hereditary breast ovarian cancer syndrome	GUncertain significance
Select item 2733506	NM_000059.4(BRCA2):c.-45G>T	LOC106721785, BRCA2	Single nucleotide variant (5 prime UTR variant +1 more)	Hereditary breast ovarian cancer syndrome	GUncertain significance
Select item 1140880	NM_000059.4(BRCA2):c.-45G>C	BRCA2, LOC106721785	Single nucleotide variant (5 prime UTR variant)	Hereditary breast ovarian cancer syndrome	GLikely benign
Select item 2127106	NM_000059.4(BRCA2):c.-43G>T	BRCA2, LOC106721785	Single nucleotide variant (5 prime UTR variant)	Hereditary breast ovarian cancer syndrome	GUncertain significance
Select item 1505260	NM_000059.4(BRCA2):c.-43G>A	BRCA2, LOC106721785	Single nucleotide variant (5 prime UTR variant)	Hereditary breast ovarian cancer syndrome	GUncertain significance
Select item 420553	NM_000059.4(BRCA2):c.-42_-41del	BRCA2, LOC106721785	Deletion (5 prime UTR variant)	Hereditary breast ovarian cancer syndrome +1 more	GLikely benign
Select item 1113812	NM_000059.4(BRCA2):c.-42C>G	BRCA2, LOC106721785	Single nucleotide variant (5 prime UTR variant)	Hereditary breast ovarian cancer syndrome	GLikely benign
Select item 701875	NM_000059.4(BRCA2):c.-42C>A	BRCA2, LOC106721785	Single nucleotide variant (5 prime UTR variant)	Hereditary breast ovarian cancer syndrome	GLikely benign
Select item 565656	NM_000059.4(BRCA2):c.-42C>T	BRCA2, LOC106721785	Single nucleotide variant (5 prime UTR variant)	Hereditary breast ovarian cancer syndrome	GUncertain significance
Select item 1418390	NM_000059.4(BRCA2):c.-41_-40+5del	BRCA2, LOC106721785	Deletion (splice donor variant)	Hereditary breast ovarian cancer syndrome	GUncertain significance
Select item 252427	NM_000059.4(BRCA2):c.-41G>A	BRCA2, LOC106721785	Single nucleotide variant (5 prime UTR variant)	Hereditary breast ovarian cancer syndrome +2 more	GConflicting classifications of pathogenicity
Select item 965884	NM_000059.4(BRCA2):c.-40G>A	BRCA2, LOC106721785	Single nucleotide variant (5 prime UTR variant)	Hereditary breast ovarian cancer syndrome	GUncertain significance
Select item 566022	NM_000059.4(BRCA2):c.-40G>T	BRCA2, LOC106721785	Single nucleotide variant (5 prime UTR variant)	Hereditary cancer-predisposing syndrome +1 more	GUncertain significance
Select item 491197	NM_000059.4(BRCA2):c.-40G>C	BRCA2, LOC106721785	Single nucleotide variant (5 prime UTR variant)	Hereditary breast ovarian cancer syndrome +1 more	GUncertain significance
Select item 2116024	NM_000059.4(BRCA2):c.-40+1G>T	BRCA2, LOC106721785	Single nucleotide variant (splice donor variant)	Hereditary breast ovarian cancer syndrome	GUncertain significance
Select item 972475	NM_000059.4(BRCA2):c.-40+1G>C	BRCA2, LOC106721785	Single nucleotide variant (splice donor variant)	Hereditary breast ovarian cancer syndrome	GUncertain significance
Select item 940200	NM_000059.4(BRCA2):c.-40+1G>A	BRCA2, LOC106721785	Single nucleotide variant (splice donor variant)	Hereditary breast ovarian cancer syndrome +1 more	GConflicting classifications of pathogenicity
Select item 2738444	NM_000059.4(BRCA2):c.-40+2T>A	BRCA2, LOC106721785	Single nucleotide variant (splice donor variant)	Hereditary breast ovarian cancer syndrome	GUncertain significance
Select item 643446	NM_000059.4(BRCA2):c.-40+2T>C	BRCA2, LOC106721785	Single nucleotide variant (splice donor variant)	Fanconi anemia complementation group D1 +2 more	GConflicting classifications of pathogenicity
Select item 2829868	NM_000059.4(BRCA2):c.-40+4_-40+6del	BRCA2, LOC106721785	Deletion (intron variant)	Hereditary breast ovarian cancer syndrome	GUncertain significance
Select item 1078246	NM_000059.4(BRCA2):c.-40+3T>C	BRCA2, LOC106721785	Single nucleotide variant (intron variant)	Hereditary breast ovarian cancer syndrome	GLikely benign
Select item 1470076	NM_000059.4(BRCA2):c.-40+4A>G	LOC106721785, BRCA2	Single nucleotide variant (intron variant)	Hereditary breast ovarian cancer syndrome	GUncertain significance
Select item 1128934	NM_000059.4(BRCA2):c.-40+5GTG[4]	BRCA2, LOC106721785	Microsatellite (intron variant)	Hereditary breast ovarian cancer syndrome	GLikely benign
Select item 2715935	NM_000059.4(BRCA2):c.-40+5G>C	BRCA2, LOC106721785	Single nucleotide variant (intron variant)	Hereditary breast ovarian cancer syndrome	GUncertain significance
Select item 2102748	NM_000059.4(BRCA2):c.-40+10_-40+15del	BRCA2, LOC106721785	Microsatellite (intron variant)	Hereditary breast ovarian cancer syndrome	GUncertain significance
Select item 419639	NM_000059.4(BRCA2):c.-40+5G>T	BRCA2, LOC106721785	Single nucleotide variant (intron variant)	Hereditary breast ovarian cancer syndrome +1 more	GUncertain significance
Select item 1058012	NM_000059.4(BRCA2):c.-40+6T>A	BRCA2, LOC106721785	Single nucleotide variant (intron variant)	Hereditary breast ovarian cancer syndrome	GUncertain significance
Select item 491196	NM_000059.4(BRCA2):c.-40+7G>A	BRCA2, LOC106721785	Single nucleotide variant (intron variant)	Hereditary breast ovarian cancer syndrome +1 more	GLikely benign
Select item 438975	NM_000059.4(BRCA2):c.-40+7G>T	BRCA2, LOC106721785	Single nucleotide variant (intron variant)	Hereditary breast ovarian cancer syndrome +4 more	GConflicting classifications of pathogenicity
Select item 1079746	NM_000059.4(BRCA2):c.-40+8G>A	BRCA2, LOC106721785	Single nucleotide variant (intron variant)	Hereditary breast ovarian cancer syndrome	GLikely benign
Select item 2047996	NM_000059.4(BRCA2):c.-40+10G>A	BRCA2, LOC106721785	Single nucleotide variant (intron variant)	Hereditary breast ovarian cancer syndrome	GLikely benign
Select item 1928974	NM_000059.4(BRCA2):c.-40+10G>T	BRCA2, LOC106721785	Single nucleotide variant (intron variant)	Hereditary breast ovarian cancer syndrome	GLikely benign
Select item 699141	NM_000059.4(BRCA2):c.-40+11G>A	BRCA2, LOC106721785	Single nucleotide variant (intron variant)	Hereditary breast ovarian cancer syndrome	GLikely benign
Select item 757255	NM_000059.4(BRCA2):c.-40+13G>A	BRCA2, LOC106721785	Single nucleotide variant (intron variant)	Hereditary breast ovarian cancer syndrome	GLikely benign
Select item 1609827	NM_000059.4(BRCA2):c.-40+14G>T	BRCA2, LOC106721785	Single nucleotide variant (intron variant)	Hereditary breast ovarian cancer syndrome	GLikely benign
Select item 2748055	NM_000059.4(BRCA2):c.-40+15T>C	BRCA2, LOC106721785	Single nucleotide variant (intron variant)	Hereditary breast ovarian cancer syndrome	GUncertain significance
Select item 1992240	NM_000059.4(BRCA2):c.-40+16A>G	BRCA2, LOC106721785	Single nucleotide variant (intron variant)	Hereditary breast ovarian cancer syndrome	GLikely benign
Select item 2731294	NM_000059.4(BRCA2):c.-40+17G>C	BRCA2, LOC106721785	Single nucleotide variant (intron variant)	Hereditary breast ovarian cancer syndrome	GUncertain significance
Select item 1118040	NM_000059.4(BRCA2):c.-40+17G>A	BRCA2, LOC106721785	Single nucleotide variant (intron variant)	Hereditary breast ovarian cancer syndrome	GLikely benign
Select item 1153827	NM_000059.4(BRCA2):c.-40+20G>A	BRCA2, LOC106721785	Single nucleotide variant (intron variant)	Hereditary breast ovarian cancer syndrome	GLikely benign
Select item 1103394	NM_000059.4(BRCA2):c.-40+20G>T	BRCA2, LOC106721785	Single nucleotide variant (intron variant)	Hereditary breast ovarian cancer syndrome	GLikely benign

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Items: 73