ClinVar

46,XX,der(6)(q25.1,q28)dn.seq[GRCh37/hg19]der(6)(6pter->6q25.2(+)(154768571)::q25.2(+)(154778901),q25.2(+)154778992::q25.2(-)(154774048),q25.2(-)(154768571)::q25.2(-)(154768571),q25.1(-)(~151443183-151443483))dn

Genes:

• AGPAT4:1-acylglycerol-3-phosphate O-acyltransferase 4 [Gene - OMIM - HGNC]
• AKAP12:A-kinase anchoring protein 12 [Gene - OMIM - HGNC]
• ARID1B:AT-rich interaction domain 1B [Gene - OMIM - HGNC]
• CCR6:C-C motif chemokine receptor 6 [Gene - OMIM - HGNC]
• CNKSR3:CNKSR family member 3 [Gene - OMIM - HGNC]
• ERMARD:ER membrane associated RNA degradation [Gene - OMIM - HGNC]
• FBXO5:F-box protein 5 [Gene - OMIM - HGNC]
• FRMD1:FERM domain containing 1 [Gene - HGNC]
• GPR31:G protein-coupled receptor 31 [Gene - OMIM - HGNC]
• MAS1:MAS1 proto-oncogene, G protein-coupled receptor [Gene - OMIM - HGNC]
• MYCT1:MYC target 1 [Gene - OMIM - HGNC]
• NOX3:NADPH oxidase 3 [Gene - OMIM - HGNC]
• PNLDC1:PARN like ribonuclease domain containing exonuclease 1 [Gene - OMIM - HGNC]
• PHF10:PHD finger protein 10 [Gene - OMIM - HGNC]
• QKI:QKI, KH domain containing RNA binding [Gene - OMIM - HGNC]
• SFT2D1:SFT2 domain containing 1 [Gene - HGNC]
• SMOC2:SPARC related modular calcium binding 2 [Gene - OMIM - HGNC]
• SCAF8:SR-related CTD associated factor 8 [Gene - OMIM - HGNC]
• SYNE1-AS1:SYNE1 antisense RNA 1 [Gene - HGNC]
• TAGAP:T cell activation RhoGTPase activating protein [Gene - OMIM - HGNC]
• TBXT:T-box transcription factor T [Gene - OMIM - HGNC]
• TBP:TATA-box binding protein [Gene - OMIM - HGNC]
• TIAM2:TIAM Rac1 associated GEF 2 [Gene - OMIM - HGNC]
• TULP4:TUB like protein 4 [Gene - OMIM - HGNC]
• WDR27:WD repeat domain 27 [Gene - HGNC]
• WTAP:WT1 associated protein [Gene - OMIM - HGNC]
• ACAT2:acetyl-CoA acetyltransferase 2 [Gene - OMIM - HGNC]
• ARMT1:acidic residue methyltransferase 1 [Gene - OMIM - HGNC]
• AFDN:afadin, adherens junction formation factor [Gene - OMIM - HGNC]
• AIRN:antisense of IGF2R non-protein coding RNA [Gene - OMIM - HGNC]
• CEP43:centrosomal protein 43 [Gene - OMIM - HGNC]
• C6orf118:chromosome 6 open reading frame 118 [Gene - HGNC]
• C6orf120:chromosome 6 open reading frame 120 [Gene - OMIM - HGNC]
• CLDN20:claudin 20 [Gene - HGNC]
• CCDC170:coiled-coil domain containing 170 [Gene - HGNC]
• DLL1:delta like canonical Notch ligand 1 [Gene - OMIM - HGNC]
• DACT2:dishevelled binding antagonist of beta catenin 2 [Gene - OMIM - HGNC]
• DYNLT1:dynein light chain Tctex-type 1 [Gene - OMIM - HGNC]
• DYNLT2:dynein light chain Tctex-type 2 [Gene - OMIM - HGNC]
• ESR1:estrogen receptor 1 [Gene - OMIM - HGNC]
• EZR:ezrin [Gene - OMIM - HGNC]
• FAM120B:family with sequence similarity 120B [Gene - OMIM - HGNC]
• FNDC1:fibronectin type III domain containing 1 [Gene - OMIM - HGNC]
• GTF2H5:general transcription factor IIH subunit 5 [Gene - OMIM - HGNC]
• IGF2R:insulin like growth factor 2 receptor [Gene - OMIM - HGNC]
• IPCEF1:interaction protein for cytohesin exchange factors 1 [Gene - OMIM - HGNC]
• KIF25:kinesin family member 25 [Gene - OMIM - HGNC]
• LPA:lipoprotein(a) [Gene - OMIM - HGNC]
• LINC02487:long intergenic non-protein coding RNA 2487 [Gene - HGNC]
• LINC02901:long intergenic non-protein coding RNA 2901 [Gene - HGNC]
• MPC1:mitochondrial pyruvate carrier 1 [Gene - OMIM - HGNC]
• MRPL18:mitochondrial ribosomal protein L18 [Gene - OMIM - HGNC]
• MTRF1L:mitochondrial translation release factor 1 like [Gene - OMIM - HGNC]
• MAP3K4:mitogen-activated protein kinase kinase kinase 4 [Gene - OMIM - HGNC]
• OPRM1:opioid receptor mu 1 [Gene - OMIM - HGNC]
• PRKN:parkin RBR E3 ubiquitin protein ligase [Gene - OMIM - HGNC]
• PACRG:parkin coregulated [Gene - OMIM - HGNC]
• PDE10A:phosphodiesterase 10A [Gene - OMIM - HGNC]
• PLG:plasminogen [Gene - OMIM - HGNC]
• PDCD2:programmed cell death 2 [Gene - OMIM - HGNC]
• PRR18:proline rich 18 [Gene - HGNC]
• PSMB1:proteasome 20S subunit beta 1 [Gene - OMIM - HGNC]
• RSPH3:radial spoke head 3 [Gene - OMIM - HGNC]
• RGS17:regulator of G protein signaling 17 [Gene - OMIM - HGNC]
• RMND1:required for meiotic nuclear division 1 homolog [Gene - OMIM - HGNC]
• RNASET2:ribonuclease T2 [Gene - OMIM - HGNC]
• RPS6KA2:ribosomal protein S6 kinase A2 [Gene - OMIM - HGNC]
• SERAC1:serine active site containing 1 [Gene - OMIM - HGNC]
• SLC22A1:solute carrier family 22 member 1 [Gene - OMIM - HGNC]
• SLC22A2:solute carrier family 22 member 2 [Gene - OMIM - HGNC]
• SLC22A3:solute carrier family 22 member 3 [Gene - OMIM - HGNC]
• SNX9:sorting nexin 9 [Gene - OMIM - HGNC]
• SYNE1:spectrin repeat containing nuclear envelope protein 1 [Gene - OMIM - HGNC]
• SDIM1:stress responsive DNAJB4 interacting membrane protein 1 [Gene - HGNC]
• SOD2:superoxide dismutase 2 [Gene - OMIM - HGNC]
• SYNJ2:synaptojanin 2 [Gene - OMIM - HGNC]
• SYTL3:synaptotagmin like 3 [Gene - HGNC]
• TCP1:t-complex 1 [Gene - OMIM - HGNC]
• THBS2:thrombospondin 2 [Gene - OMIM - HGNC]
• TFB1M:transcription factor B1, mitochondrial [Gene - OMIM - HGNC]
• TMEM181:transmembrane protein 181 [Gene - OMIM - HGNC]
• TMEM242:transmembrane protein 242 [Gene - HGNC]
• TTLL2:tubulin tyrosine ligase like 2 [Gene - HGNC]
• UNC93A:unc-93 homolog A [Gene - OMIM - HGNC]
• LOC729681:uncharacterized LOC729681 [Gene]
• VIP:vasoactive intestinal peptide [Gene - OMIM - HGNC]
• ZDHHC14:zinc finger DHHC-type palmitoyltransferase 14 [Gene - OMIM - HGNC]
• ZBTB2:zinc finger and BTB domain containing 2 [Gene - OMIM - HGNC]

Variant type:

Complex

Cytogenetic location:

6q25.1-27

Genomic location:

Chr6: 151443333 - 171115067 (on Assembly GRCh37)

Preferred name:

46,XX,der(6)(q25.1,q28)dn.seq[GRCh37/hg19]der(6)(6pter->6q25.2(+)(154768571)::q25.2(+)(154778901),q25.2(+)154778992::q25.2(-)(154774048),q25.2(-)(154768571)::q25.2(-)(154768571),q25.1(-)(~151443183-151443483))dn