GEO DataSets

(Submitter supplied) Polymicrobial biofilms are of large medical importance, but little is known about their physiology and the underlying interspecies interactions. Here we studied two human pathogens, the opportunistic fungus Candida albicans and the caries promoting bacterium Streptococcus mutans. Both species formed biofilms in monoculture, with C. albicans growing mainly in the virulence-associated hyphae form, and S. more...

Organism:

Candida albicans; Streptococcus mutans UA159

Type:

Expression profiling by array

Platform:

GPL10540

16 Samples

Download data: TXT

(Submitter supplied) Transcriptional profiling of carolacton-treated Streptococcus mutans biofilm cells in comparison to untreated biofilms in a time series approach.

Organism:

Streptococcus mutans UA159

Type:

Expression profiling by array

Platform:

GPL10540

22 Samples

Download data: TXT

(Submitter supplied) Transcriptional profiling of carolacton treated S. mutans biofilm cells in comparison to untreated biofilms in a time series approach.

Organism:

Streptococcus mutans UA159

Type:

Expression profiling by array

Platform:

GPL10540

24 Samples

Download data: TXT

(Submitter supplied) Transcriptional profiling of carolacton treated S. mutans biofilm cells in comparison to untreated biofilms after 8h of growth.

Organism:

Streptococcus mutans UA159

Type:

Expression profiling by array

Platform:

GPL10540

8 Samples

Download data: TXT

(Submitter supplied) Transcriptional profiling of the competence-stimulating peptide (CSP) response in Streptococcus mutans of FACS-separated subpopulations and mixed cells of a clonal culture. CSP-mediated competence development in S. mutans is a transient and biphasic process since only a subpopulation induces expression of ComX in the presence of CSP and activation of the DNA uptake machinery in this fraction shuts down ~3-4 hours post induction. more...

Organism:

Streptococcus mutans UA159; Streptococcus mutans

Type:

Expression profiling by array

Platform:

GPL10540

6 Samples

Download data: TXT

(Submitter supplied) Transcriptional profiling of S. mutans rpoE knockout mutant comparing to the wild type. The mutation of rpoE cause dramatic changes in phenotypes. The goal is to determine the genes affected by rpoE. The delta subunit of RNA polymerase, RpoE, is wide spread in low G+C Gram-positive bacteria and is thought to play a role in enhancing transcriptional specificity by blocking RNA polymerase binding at weak-promoter sites and stimulating RNA synthesis by accelerating core enzyme recycling. more...

Organism:

Streptococcus mutans UA159

Type:

Expression profiling by array

Platform:

GPL10540

15 Samples

Download data: TXT