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Items: 1 to 20 of 371

1.

microRNAs profiling in hippocampal cells of Self-Sustaining Status Epilepticus (SSSE) mouse model

(Submitter supplied) Status Epilepticus (SE) is induced in mice (C57Bl/6J) through electrical stimulation (90min, 100 ms trains of 1 ms, 2 trains per 1 s, 250 μA peak current intensity). RNA was extracted from the hippocampi at 24 h and 28 d after induction. In wild-type RNA was extracted on the 22nd day. microRNA expressions were measured via microarray technology using Exiqon's miCURY™ LNA Arrays.
Organism:
Homo sapiens; Merkel cell polyomavirus; Rattus norvegicus; Human alphaherpesvirus 2; JC polyomavirus; Murid gammaherpesvirus 4; Betapolyomavirus hominis; Mus musculus; Human immunodeficiency virus 1; Human gammaherpesvirus 8; Human alphaherpesvirus 1; Human betaherpesvirus 5; human gammaherpesvirus 4; Mus musculus cytomegalovirus 2; Betapolyomavirus macacae
Type:
Non-coding RNA profiling by array
Platform:
GPL11432
24 Samples
Download data: TXT
Series
Accession:
GSE51842
ID:
200051842
2.

microRNAs profiling in hippocampal cells of mouse with Pilocarpine-induced Status Epilepticus (SE)

(Submitter supplied) SE was induced in mice (NMRI) chemically by a single dose of Pilocarpine (300mg/kg;i.p.). RNA was extracted from the hippocampi of treated and wild-type mice at 24 h and 28 d after induction. microRNA expressions were measured via microarray technology using Exiqon's miCURY™ LNA Arrays.
Organism:
Merkel cell polyomavirus; Rattus norvegicus; Human alphaherpesvirus 2; Murid gammaherpesvirus 4; Betapolyomavirus hominis; Homo sapiens; Human alphaherpesvirus 1; Human betaherpesvirus 5; human gammaherpesvirus 4; Mus musculus cytomegalovirus 2; Betapolyomavirus macacae; Mus musculus; JC polyomavirus; Human immunodeficiency virus 1; Human gammaherpesvirus 8
Type:
Non-coding RNA profiling by array
Platform:
GPL11432
32 Samples
Download data: TXT
Series
Accession:
GSE51841
ID:
200051841
3.

microRNAs profiling in hippocampal cells of mouse with Sound-induced Seizure

(Submitter supplied) After an electrically induced seizure, mice (NMRI) received electrical stimulation (current intensity 44 mA, 0.2 ms monopolar pulses at 6 Hz frequency for 3 s). RNA was extracted from the hippocampi at 0, 3, 6, 24 and 72 h after the seizure. microRNA expressions were measured via microarray technology using Exiqon's miCURY™ LNA Arrays.
Organism:
Mus musculus cytomegalovirus 2; Human alphaherpesvirus 2; Murid gammaherpesvirus 4; Betapolyomavirus hominis; Mus musculus; Rattus norvegicus; JC polyomavirus; Human immunodeficiency virus 1; Human gammaherpesvirus 8; Merkel cell polyomavirus; Homo sapiens; Human alphaherpesvirus 1; Human betaherpesvirus 5; human gammaherpesvirus 4; Betapolyomavirus macacae
Type:
Non-coding RNA profiling by array
Platform:
GPL11432
35 Samples
Download data: TXT
Series
Accession:
GSE51840
ID:
200051840
4.

Expression signatures in heart tissues of mice simulating posttraumatic stress disorder (PTSD)

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
human gammaherpesvirus 4; Human gammaherpesvirus 8; Mus musculus cytomegalovirus 2; Betapolyomavirus macacae; Human alphaherpesvirus 1; Human alphaherpesvirus 2; Homo sapiens; Human betaherpesvirus 5; Murid gammaherpesvirus 4; Betapolyomavirus hominis; Mus musculus; Rattus norvegicus; Murid betaherpesvirus 1; JC polyomavirus; Human immunodeficiency virus 1; Merkel cell polyomavirus
Type:
Expression profiling by array; Non-coding RNA profiling by array
Platforms:
GPL13912 GPL11432 GPL11434
96 Samples
Download data: TXT
Series
Accession:
GSE52875
ID:
200052875
5.

miRNA expression signatures in heart tissues of mice simulating posttraumatic stress disorder (PTSD) [Study1]

(Submitter supplied) Using a PTSD mouse model, we investigated the longitudinal transcriptomic changes in heart tissues after the exposure to stress through intimidation
Organism:
Rattus norvegicus; Human alphaherpesvirus 2; Murid gammaherpesvirus 4; Betapolyomavirus hominis; Homo sapiens; Merkel cell polyomavirus; Mus musculus; JC polyomavirus; Human immunodeficiency virus 1; Human gammaherpesvirus 8; Human alphaherpesvirus 1; Human betaherpesvirus 5; human gammaherpesvirus 4; Mus musculus cytomegalovirus 2; Betapolyomavirus macacae
Type:
Non-coding RNA profiling by array
Platform:
GPL11432
32 Samples
Download data: CSV
Series
Accession:
GSE52869
ID:
200052869
6.

TAL1 regulated miRNAs

(Submitter supplied) miRNA profiling of Jurkat T-ALL cells after knockdown with two control shRNAs and two shRNAs targeting TAL1 to identify miRNAs that are regulated by TAL1
Organism:
human gammaherpesvirus 4; JC polyomavirus; Human gammaherpesvirus 8; Mus musculus cytomegalovirus 2; Betapolyomavirus macacae; Mus musculus; Human alphaherpesvirus 1; Human betaherpesvirus 5; Human immunodeficiency virus 1; Homo sapiens; Murid gammaherpesvirus 4; Betapolyomavirus hominis; Rattus norvegicus; Human alphaherpesvirus 2; Merkel cell polyomavirus
Type:
Non-coding RNA profiling by array
Platform:
GPL11432
8 Samples
Download data: TXT
Series
Accession:
GSE46957
ID:
200046957
7.

Sensitivity of cholangiocarcinoma cells to gemcitabine is affected by microRNA expression

(Submitter supplied) We examined the relationship between miRNA expression and the sensitivity of CCA cells to Gem. Two intrahepatic CCA cell lines, HuH28 and HuCCT1 were used. HuCCT1 cells were more sensitive to Gem than were HuH28 cells. The miRNA expression profiles of HuH28 and HuCCT1 were determined by microarray analysis. Eighteen miRNAs were differentially expressed whose ratios over ± 2log2 between HuH28 and HuCCT1. more...
Organism:
Homo sapiens; Merkel cell polyomavirus; Rattus norvegicus; Human alphaherpesvirus 2; Murid gammaherpesvirus 4; Betapolyomavirus hominis; Mus musculus; JC polyomavirus; Human immunodeficiency virus 1; Human gammaherpesvirus 8; Human alphaherpesvirus 1; Human betaherpesvirus 5; human gammaherpesvirus 4; Mus musculus cytomegalovirus 2; Betapolyomavirus macacae
Type:
Non-coding RNA profiling by array
Platform:
GPL11432
4 Samples
Download data: TXT
Series
Accession:
GSE47396
ID:
200047396
8.

Involvement of miRNAs in the Differentiation of Human Glioblastoma Multiforme Brain Tumor Stem-Like Cells

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus; Human alphaherpesvirus 1; Human betaherpesvirus 5; Human immunodeficiency virus 1; human gammaherpesvirus 4; JC polyomavirus; Human gammaherpesvirus 8; Mus musculus cytomegalovirus 2; Betapolyomavirus macacae; Rattus norvegicus; Human alphaherpesvirus 2; Merkel cell polyomavirus; Homo sapiens; Murid gammaherpesvirus 4; Betapolyomavirus hominis
Type:
Expression profiling by array; Non-coding RNA profiling by array
Platforms:
GPL570 GPL11432
23 Samples
Download data: CEL, TXT
Series
Accession:
GSE44843
ID:
200044843
9.

Involvement of miRNAs in the induced differentiation of glioblastoma multiforme brain tumor stem-like cells [Exiqon miRNA array]

(Submitter supplied) Brain tumor neurospheres (BTCSs) are cancer cells with neural stem cell-like properties found in the fatal brain tumor glioblastoma multiforme (GBM). These cells account for less than 1% of total tumor cells, are poorly differentiated and are believed to be involved in tumor induction, progression, treatment resistance and relapse. Specific miRNAs play important roles in modulating the proliferation and differentiation of neural stem cells, therefore, we aimed to identify miRNAs controlling differentiation in GBM-BTSCs through high throughput screening miRNA array profiling. more...
Organism:
Homo sapiens; Mus musculus; Human alphaherpesvirus 1; Human betaherpesvirus 5; Human immunodeficiency virus 1; human gammaherpesvirus 4; JC polyomavirus; Human gammaherpesvirus 8; Betapolyomavirus macacae; Murid gammaherpesvirus 4; Betapolyomavirus hominis; Rattus norvegicus; Human alphaherpesvirus 2; Merkel cell polyomavirus; Mus musculus cytomegalovirus 2
Type:
Non-coding RNA profiling by array
Platform:
GPL11432
15 Samples
Download data: TXT
Series
Accession:
GSE44842
ID:
200044842
10.

miRNA in human lung fibroblasts

(Submitter supplied) By employing miRCURY™ LNA array, we have identified a subset (79) of the total number of miRNAs that are differentially expressed in TGF beta1-treated human lung fibroblasts MRC-5 cells, as compared to untreated control cells
Organism:
Mus musculus; Human alphaherpesvirus 1; Human alphaherpesvirus 2; human gammaherpesvirus 4; Human gammaherpesvirus 8; Mus musculus cytomegalovirus 2; Betapolyomavirus macacae; Homo sapiens; Human betaherpesvirus 5; Murid gammaherpesvirus 4; Betapolyomavirus hominis; Rattus norvegicus; JC polyomavirus; Human immunodeficiency virus 1; Merkel cell polyomavirus
Type:
Non-coding RNA profiling by array
Platform:
GPL11432
9 Samples
Download data: TXT
Series
Accession:
GSE43992
ID:
200043992
11.

Benzo[a]pyrene-induced changes in microRNA-mRNA networks

(Submitter supplied) The microarray contains 9360 reporters, each present four times on the microarray. In our analysis 1326 human and viral reporters were used, of which 880 are unique human mature microRNAs. The other 8024 reporters represent microRNAs from other species. cDNA was generated using 1 μg of total RNA per sample. RNA was labeled only with Hy3 containing dye using the microRNACURY LNA™ microRNA Hy3 Power labeling kit (Exiqon, Denmark) according to the manufacturer’s protocol in a total volume of 25 μl. more...
Organism:
Mus musculus; JC polyomavirus; Human immunodeficiency virus 1; Human gammaherpesvirus 8; Homo sapiens; Merkel cell polyomavirus; Rattus norvegicus; Human alphaherpesvirus 2; Murid gammaherpesvirus 4; Betapolyomavirus hominis; Human alphaherpesvirus 1; Human betaherpesvirus 5; human gammaherpesvirus 4; Mus musculus cytomegalovirus 2; Betapolyomavirus macacae
Type:
Non-coding RNA profiling by array
Platform:
GPL11432
24 Samples
Download data: GPR
Series
Accession:
GSE31252
ID:
200031252
12.

A TARBP2-dependent miRNA expression profile determines cancer stem cell properties and provides new candidate therapeutic reagents in Ewing's sarcoma

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Rattus norvegicus; Human alphaherpesvirus 2; Merkel cell polyomavirus; Mus musculus cytomegalovirus 2; human gammaherpesvirus 4; JC polyomavirus; Human gammaherpesvirus 8; Betapolyomavirus macacae; Homo sapiens; Mus musculus; Human alphaherpesvirus 1; Human betaherpesvirus 5; Human immunodeficiency virus 1; Murid gammaherpesvirus 4; Betapolyomavirus hominis
Type:
Non-coding RNA profiling by array
Platform:
GPL11432
18 Samples
Download data: TXT
Series
Accession:
GSE31146
ID:
200031146
13.

MicroRNA expression profiling of Ewing sarcoma spheres vs. adherent cells

(Submitter supplied) We have recently demonstrated that human paediatric mesenchymal stem cells can be reprogrammed toward a Ewing’s sarcoma family tumor (ESFT) cancer stem cell (CSC) phenotype by mechanisms that implicate microRNAs (miRNAs). Here, we show that the miRNA profile of ESFT CSC is shared by embryonic stem cells and CSC from divergent tumor types. We also provide evidence that the miRNA profile of ESFT CSC is the result of reversible disruption of TARBP2-dependent miRNA maturation. more...
Organism:
Murid gammaherpesvirus 4; Rattus norvegicus; JC polyomavirus; Human gammaherpesvirus 8; Betapolyomavirus hominis; Homo sapiens; Mus musculus; Human alphaherpesvirus 1; Human betaherpesvirus 5; Human immunodeficiency virus 1; Merkel cell polyomavirus; Human alphaherpesvirus 2; human gammaherpesvirus 4; Mus musculus cytomegalovirus 2; Betapolyomavirus macacae
Type:
Non-coding RNA profiling by array
Platform:
GPL11432
4 Samples
Download data: TXT
Series
Accession:
GSE31145
ID:
200031145
14.

MicroRNA expression profiling of Ewing sarcoma cell lines upon TARBP2 depletion

(Submitter supplied) We have recently demonstrated that human paediatric mesenchymal stem cells can be reprogrammed toward a Ewing’s sarcoma family tumor (ESFT) cancer stem cell (CSC) phenotype by mechanisms that implicate microRNAs (miRNAs). Here, we show that the miRNA profile of ESFT CSC is shared by embryonic stem cells and CSC from divergent tumor types. We also provide evidence that the miRNA profile of ESFT CSC is the result of reversible disruption of TARBP2-dependent miRNA maturation. more...
Organism:
Human alphaherpesvirus 1; Human betaherpesvirus 5; human gammaherpesvirus 4; Mus musculus cytomegalovirus 2; Betapolyomavirus macacae; Rattus norvegicus; Human alphaherpesvirus 2; JC polyomavirus; Murid gammaherpesvirus 4; Betapolyomavirus hominis; Homo sapiens; Merkel cell polyomavirus; Mus musculus; Human immunodeficiency virus 1; Human gammaherpesvirus 8
Type:
Non-coding RNA profiling by array
Platform:
GPL11432
6 Samples
Download data: TXT
Series
Accession:
GSE31144
ID:
200031144
15.

MicroRNA expression profiling of Ewing sarcoma cancer stem cells

(Submitter supplied) We have recently demonstrated that human paediatric mesenchymal stem cells can be reprogrammed toward a Ewing’s sarcoma family tumor (ESFT) cancer stem cell (CSC) phenotype by mechanisms that implicate microRNAs (miRNAs). Here, we show that the miRNA profile of ESFT CSC is shared by embryonic stem cells and CSC from divergent tumor types. We also provide evidence that the miRNA profile of ESFT CSC is the result of reversible disruption of TARBP2-dependent miRNA maturation. more...
Organism:
Homo sapiens; Murid gammaherpesvirus 4; Betapolyomavirus hominis; human gammaherpesvirus 4; Human gammaherpesvirus 8; Mus musculus cytomegalovirus 2; Betapolyomavirus macacae; Mus musculus; Human alphaherpesvirus 1; Human betaherpesvirus 5; Human immunodeficiency virus 1; Rattus norvegicus; Human alphaherpesvirus 2; JC polyomavirus; Merkel cell polyomavirus
Type:
Non-coding RNA profiling by array
Platform:
GPL11432
8 Samples
Download data: TXT
Series
Accession:
GSE30513
ID:
200030513
16.

microRNA expression analysis of circulating monocytes in obese patients

(Submitter supplied) Low-grade chronic inflammation plays an important role in the development of obesity and obesity-associated disorders such as insulin resistance, type 2 diabetes, the metabolic syndrome and atherosclerosis. One possible link between obesity and inflammation is the enhanced activation of circulating monocytes making them more prone to infiltration into the adipose and vascular tissues of obese persons. more...
Organism:
human gammaherpesvirus 4; Human gammaherpesvirus 8; Mus musculus cytomegalovirus 2; Betapolyomavirus macacae; Mus musculus; Human alphaherpesvirus 1; Human betaherpesvirus 5; Human immunodeficiency virus 1; Homo sapiens; Murid gammaherpesvirus 4; Betapolyomavirus hominis; Rattus norvegicus; Human alphaherpesvirus 2; JC polyomavirus; Merkel cell polyomavirus
Type:
Non-coding RNA profiling by array
Platform:
GPL11432
15 Samples
Download data: TXT
Series
Accession:
GSE34223
ID:
200034223
17.

Identification of XMRV Infection-Associated microRNAs in Four Cell Types in Culture

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens; Mus musculus; Human betaherpesvirus 5; Human immunodeficiency virus 1; Merkel cell polyomavirus; Rattus norvegicus; JC polyomavirus; Murid gammaherpesvirus 4; Betapolyomavirus hominis; Human gammaherpesvirus 8; Human alphaherpesvirus 1; Human alphaherpesvirus 2; human gammaherpesvirus 4; Mus musculus cytomegalovirus 2; Betapolyomavirus macacae
Type:
Non-coding RNA profiling by array
Platform:
GPL11432
48 Samples
Download data: TXT
Series
Accession:
GSE37788
ID:
200037788
18.

Identification of XMRV Infection-Associated microRNAs in Four Cell Types in Culture (Experiment B)

(Submitter supplied) XMRV is a gammaretrovirus that was thought to be associated with prostate cancer (PC) and chronic fatigue syndrome (CFS) in humans until recently. The virus is culturable in various cells of human origin like lymphocytes, NK cells, neuronal cells, and prostate cell lines. MicroRNAs (miRNAs), which regulate gene expression, were so far not identified in cells infected with XMRV in culture. Two prostate cancer cell lines (LNCaP and DU145) and two primary cells (peripheral blood lymphocytes (PBLs) and monocyte-derived macrophages (MDMs)) were infected with XMRV. more...
Organism:
Homo sapiens; Merkel cell polyomavirus; Rattus norvegicus; Human alphaherpesvirus 2; JC polyomavirus; Murid gammaherpesvirus 4; Betapolyomavirus hominis; Human alphaherpesvirus 1; Human betaherpesvirus 5; human gammaherpesvirus 4; Mus musculus cytomegalovirus 2; Betapolyomavirus macacae; Mus musculus; Human immunodeficiency virus 1; Human gammaherpesvirus 8
Type:
Non-coding RNA profiling by array
Platform:
GPL11432
24 Samples
Download data: TXT
Series
Accession:
GSE37787
ID:
200037787
19.

Identification of XMRV Infection-Associated microRNAs in Four Cell Types in Culture (Experiment A)

(Submitter supplied) XMRV is a gammaretrovirus that was thought to be associated with prostate cancer (PC) and chronic fatigue syndrome (CFS) in humans until recently. The virus is culturable in various cells of human origin like lymphocytes, NK cells, neuronal cells, and prostate cell lines. MicroRNAs (miRNAs), which regulate gene expression, were so far not identified in cells infected with XMRV in culture. Two prostate cancer cell lines (LNCaP and DU145) and two primary cells (peripheral blood lymphocytes (PBLs) and monocyte-derived macrophages (MDMs)) were infected with XMRV. more...
Organism:
Homo sapiens; Merkel cell polyomavirus; Rattus norvegicus; Human alphaherpesvirus 2; Murid gammaherpesvirus 4; Betapolyomavirus hominis; Mus musculus; JC polyomavirus; Human immunodeficiency virus 1; Human gammaherpesvirus 8; Human alphaherpesvirus 1; Human betaherpesvirus 5; human gammaherpesvirus 4; Mus musculus cytomegalovirus 2; Betapolyomavirus macacae
Type:
Non-coding RNA profiling by array
Platform:
GPL11432
24 Samples
Download data: TXT
Series
Accession:
GSE37786
ID:
200037786
20.

Whole blood microRNA expression profiles in human non-small cell lung adenocarcinoma

(Submitter supplied) Fifth generation Exiqon® locked nucleic acid miRCURY™ LNA microarrays were used to profile the expression of microRNAs in whole blood of patients with non-small cell lung adenocarcinoma and of clinically relevant controls without the disease.
Organism:
Rattus norvegicus; Human alphaherpesvirus 2; Merkel cell polyomavirus; Mus musculus cytomegalovirus 2; human gammaherpesvirus 4; JC polyomavirus; Human gammaherpesvirus 8; Betapolyomavirus macacae; Homo sapiens; Mus musculus; Human alphaherpesvirus 1; Human betaherpesvirus 5; Human immunodeficiency virus 1; Murid gammaherpesvirus 4; Betapolyomavirus hominis
Type:
Non-coding RNA profiling by array
Platform:
GPL11432
45 Samples
Download data: TXT
Series
Accession:
GSE27486
ID:
200027486
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