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Comparative genomics reveals new molecular targets for accelerated strain improvement of rifamycin B-producing strains

(Submitter supplied) In the present study, we have used a genomic approach to understand how the classical mutate-and-screen method actually generated an improved rifamycin B producer. Compared with the reference strains Amycolatopsis mediterranei S699 (rifamycin B producer) and U32 (rifamycin SV producer), a total of 250 variations affecting a total of 227 coding sequences (CDS) were found in rifamycin B overproducing strain HP-130. more...
Organism:
Amycolatopsis mediterranei S699
Type:
Expression profiling by array
Platform:
GPL17744
20 Samples
Download data: CEL
Series
Accession:
GSE51015
ID:
200051015

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