GPL18319[RGSE] - GEO DataSets

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Items: 4

Select item 2000859821.

Clostridium difficile Biofilm with and without deoxycholate at 48H

(Submitter supplied) To understand the molecular mechanisms induced by deoxycholate (DCA) during biofilm formation and to identify factors implicated in the strong density of biofilms in this condition, we performed a transcriptomic analysis using microarrays. The microarrays were used to compare C. difficile transcription profiles of a 48 h biofilm (in BHISG medium) treated with DCA with an untreated biofilm.

Organism:: Clostridioides difficile

Type:: Expression profiling by array

Platform:: GPL18319
4 Samples

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Accession:: GSE85982

ID:: 200085982

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000859812.

Global transcriptional control by the alternative sigma factor SigB in Clostridium difficile

(Submitter supplied) Genes encoding the alternative sigma factor SigmaB, involved in the general stress response in firmicutes, as well as its regulators are present in the genome of the enteropathogen Clostridium difficile. We inactivated the sigB gene using the ClosTron technology in order to identify the role of this sigma factor in the physiology of this bacterium. Transcriptomic experiments showed that SigB positively and negatively controlls several genes involved in different cellular processes such as metabolism, sporulation and stress response.