GEO DataSets

(Submitter supplied) Oxidative stress is a key attribute that one should considered when using yeast cells for industrial applications due to its direct impact on yeast growth, viability, and productivity. However, little information is currently available regarding the molecular mechanisms of oxidative stress induction and the antioxidant response to increased reactive oxygen species (ROS) in yeasts. In this study, we generated experimentally evolved and genetically stable oxidative stress-resistant S. more...

Organism:

Saccharomyces cerevisiae

Type:

Non-coding RNA profiling by array

Platform:

GPL22543

6 Samples

Download data: TXT

(Submitter supplied) Continuous cultures assure the invariability of environmental conditions and the metabolic state of cultured microorganisms, whereas batch-cultured cells undergo constant changes in nutrients availability. For that reason, continuous culture is sometimes employed in the whole transcriptome, whole proteome, or whole metabolome studies. However, the typical method for establishing uniform growth of a cell population, i.e., by limited chemostat, results in the enrichment of the cell population gene pool with mutations adaptive for starvation conditions. more...

Organism:

Saccharomyces cerevisiae W303; Saccharomyces cerevisiae

Type:

Expression profiling by array

Platform:

GPL22543

3 Samples

Download data: TXT, XLSX

(Submitter supplied) To determine how TORC1 and PKA cooperate to regulate cell growth, we performed temporal analysis of gene expression in yeast switched from a non-fermentable substrate, to glucose, in the presence and absence of TORC1 and PKA inhibitors. Quantitative analysis of these data reveals that PKA drives the expression of key cell growth genes during transitions into, and out of, the rapid growth state in glucose, while TORC1 is important for the steady-state expression of the same genes.

Organism:

Saccharomyces cerevisiae

Type:

Expression profiling by array

Platform:

GPL22543

21 Samples

Download data: GPR

(Submitter supplied) A Saccharomyces cerevisiae mutant with improved coniferyl aldehyde resistance was obtained by using an evolutionary engineering strategy, based on successive batch cultivation under gradually increased coniferyl aldehyde concentration. The mutant strain BH13 was selected which could grow at a coniferyl aldehyde concentration that the reference strain could not grow at all. Whole-genome transcriptomic analysis of BH13 with respect to the reference strain was performed to identify differences in gene expression levels between the two strains.

Organism:

Saccharomyces cerevisiae

Type:

Expression profiling by array

Platform:

GPL22543

6 Samples

Download data: TXT

(Submitter supplied) To monitor changes in the transcriptome following activation of Hog1 per se, we used a previously established inducible expression system of intrinsically active Hog1 proteins

Organism:

Saccharomyces cerevisiae

Type:

Expression profiling by array

Platform:

GPL22543

16 Samples

Download data: TXT

(Submitter supplied) Excess cysteine (and cystine) is known to be toxic in organisms. Due to the absence of cysteine dioxygenase (involved in degradation of excess cysteine in humans and pathogenic fungi) in non pathogenic fungi such as S. cerevisiae, mechanism of cysteine (and cystine) tolerance is yet to be addressed.

Organism:

Saccharomyces cerevisiae

Type:

Expression profiling by array

Platform:

GPL22543

8 Samples

Download data: TXT