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Items: 5

1.

The Regulation of MicroRNA-21 by Interleukin-6 and its Role in the Development of Fibrosis in Endometriotic Lesions

(Submitter supplied) Endometriosis is one of the most common causes of chronic pelvic pain and infertility that affects 10% of women of reproductive age. It is currently defined as the presence of endometrial epithelial and stromal cells at ectopic sites; however, advances in endometriosis research have some authors believing that endometriosis should be re-defined as “a fibrotic condition in which endometrial stroma and epithelium can be identified”. more...
Organism:
Papio anubis
Type:
Non-coding RNA profiling by high throughput sequencing
Platform:
GPL23487
24 Samples
Download data: XLSX
Series
Accession:
GSE274922
ID:
200274922
2.

Multipotent bone marrow cell-seeded polymeric composites drive long-term, definitive urinary bladder tissue regeneration

(Submitter supplied) To date, there are no efficacious translational solutions for end-stage urinary bladder dysfunction. Current surgical strategies including urinary diversion and bladder augmentation enterocystoplasty (BAE) utilize autologous intestinal segments (e.g. ileum) to increase bladder capacity to protect renal function. Considered the standard of care, BAE is fraught with numerous short- and long-term clinical complications. more...
Organism:
Papio anubis
Type:
Expression profiling by high throughput sequencing
Platform:
GPL23487
28 Samples
Download data: TXT
Series
Accession:
GSE254204
ID:
200254204
3.

Evolutionary transcriptomics implicates HAND2 in the origins of implantation and regulation of gestation length

(Submitter supplied) The developmental origins and evolutionary histories of cell types, tissues and organ systems contribute to the ways in which their dysfunction leads to disease. In mammals for example, the nature and extent of maternal-fetal interactions, how those interactions develop, and their evolutionary history likely influence diseases of pregnancy such as infertility and preterm birth. Here we show genes that evolved to be expressed at the maternal-fetal interface in Eutherian (‘Placental') mammals play essential roles in the evolution of pregnancy and are associated with immune system disorders and preterm birth. more...
Organism:
Mus musculus; Papio anubis; Mesocricetus auratus; Carollia perspicillata; Ictidomys tridecemlineatus
Type:
Expression profiling by high throughput sequencing
5 related Platforms
16 Samples
Download data: TXT
Series
Accession:
GSE155170
ID:
200155170
4.

RNASeq of mouse, human, and non-human primate primary dermal fibroblasts to poly(I:C) transfection

(Submitter supplied) Here, we performed RNA-Seq on mRNA isolated from primary dermal fibroblasts of human, mice and multiple non-human primate species transfected with polyinosinic-polycytidylic acid (polyI:C), a synthetic dsRNA analog that invokes a strong interferon-mediated response, or mock transfected.
Organism:
Pan paniscus; Saimiri sciureus; Gorilla gorilla; Pongo abelii; Mus musculus; Pan troglodytes; Macaca mulatta; Macaca nemestrina; Papio anubis; Homo sapiens
Type:
Expression profiling by high throughput sequencing
14 related Platforms
197 Samples
Download data: TXT
Series
Accession:
GSE105160
ID:
200105160
5.

Diurnal transcriptome atlas of a primate across all major neural and peripheral tissues

(Submitter supplied) Spatio-temporal gene expression patterns underlie time-of-the day specific functional specialization of different organs. Although circadian gene expression atlases from model organisms including the nocturnal mouse are available, they are limited to a few peripheral organs. Here we report the circadian transcriptome of 64 different tissues, including 22 different brain regions, sampled every 2 h over 24 h, from the diurnal primate Papio Anubis. more...
Organism:
Papio anubis
Type:
Expression profiling by high throughput sequencing
Platform:
GPL23487
767 Samples
Download data: CSV
Series
Accession:
GSE98965
ID:
200098965
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Supplemental Content

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