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1.

Multi-scale architecture of archaeal chromosomes

(Submitter supplied) Chromosome conformation capture (3C) technologies have identified topologically associating domains (TADs) and larger A/B compartments as two salient structural features of eukaryotic chromosomes. These structures are sculpted by the combined actions of transcription and structural maintenance of chromosomes (SMC) superfamily proteins. Bacterial chromosomes fold into TAD-like chromosomal interaction domains (CIDs) but do not display A/B compartment-type organization. more...
Organism:
Saccharolobus islandicus; Sulfolobus acidocaldarius
Type:
Expression profiling by high throughput sequencing; Other
Platforms:
GPL26275 GPL26274
31 Samples
Download data: TXT
Series
Accession:
GSE159537
ID:
200159537
2.

Physical and functional compartmentalization of archaeal chromosomes

(Submitter supplied) The three-dimensional organization of chromosomes can have a profound impact on their replication and expression. The chromosomes of higher eukaryotes possess discrete compartments that are characterized by differing transcriptional activities. Contrastingly, most bacterial chromosomes have simpler organization with local domains, the boundaries of which are influenced by gene expression. Numerous studies have revealed that the higher-order architectures of bacterial and eukaryotic chromosomes are dependent on the actions of Structural Maintenance of Chromosomes (SMC) superfamily protein complexes, in particular the near-universal condensin complex. more...
Organism:
Sulfolobus acidocaldarius; Saccharolobus islandicus
Type:
Other; Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing
4 related Platforms
94 Samples
Download data: TXT
Series
Accession:
GSE128063
ID:
200128063

Supplemental Content

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