GEO DataSets

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Halobacterium salinarum

Type:

Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing

Platforms:

GPL30532 GPL28343

64 Samples

Download data: TXT, WIG

(Submitter supplied) Unlike the characterised histone proteins of a number of methanogenic and themophilic archaea, previous research indicated that HpyA, the sole histone encoded in the model halophile Halobacterium salinarum, is not involved in DNA packaging. Instead, it was found to have widespread but subtle effects on gene expression, and affect cell morphology. Here we report that HpyA is important for growth in reduced salinity and regulates gene expression of ion uptake and nucleotide metabolism pathways in a salt-dependent manner. more...

Organism:

Halobacterium salinarum

Type:

Genome binding/occupancy profiling by high throughput sequencing

Platform:

GPL28343

40 Samples

Download data: WIG

(Submitter supplied) Precise control of the cell cycle is central to the physiology of all cells. In prior work we demonstrated that archaeal cells maintain a constant cell size; however, the regulatory mechanisms underlying the cell cycle remain unexplored in this domain of life. In this study we use genetics, functional genomics, and quantitative imaging to identify and characterize the CdrSL gene regulatory network in a model species of archaea. more...

Organism:

Halobacterium salinarum

Type:

Genome binding/occupancy profiling by high throughput sequencing

Platform:

GPL28343

16 Samples

Download data: BED, WIG