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Items: 16

1.

CFTR Represses a PDX1 Axis to Govern Pancreatic Ductal Cell Fate [Bulk ATAC-seq]

(Submitter supplied) Inflammation, acinar cell destruction, and ductal cell hyperplasia drive pancreatic remodeling in newborns with cystic fibrosis (CF) lacking a functional CFTR channel. In neonatal CF ferrets, these changes are associated with a transient phase of glucose intolerance that involves islet destruction and subsequent regeneration near hyperplastic ducts. Little is known about the phenotypic changes in CF ductal epithelium and its potential impact on islet function. more...
Organism:
Mustela putorius furo
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL34388
7 Samples
Download data: BED
Series
Accession:
GSE264021
ID:
200264021

2.

CFTR Represses a PDX1 Axis to Govern Pancreatic Ductal Cell Fate [Bulk RNA-seq]

(Submitter supplied) Inflammation, acinar cell destruction, and ductal cell hyperplasia drive pancreatic remodeling in newborns with cystic fibrosis (CF) lacking a functional CFTR channel. In neonatal CF ferrets, these changes are associated with a transient phase of glucose intolerance that involves islet destruction and subsequent regeneration near hyperplastic ducts. Little is known about the phenotypic changes in CF ductal epithelium and its potential impact on islet function. more...
Organism:
Mustela putorius furo
Type:
Expression profiling by high throughput sequencing
Platform:
GPL34388
6 Samples
Download data: CSV
Series
Accession:
GSE264019
ID:
200264019

3.

Illumina HiSeq 4000 (Mustela putorius furo)

Organism:
Mustela putorius furo
2 Series
13 Samples
Download data
Platform
Accession:
GPL34388
ID:
100034388

4.

ATAC WT, donor4

Organism:
Mustela putorius furo
Source name:
Polarized pancreatic ductal epithelia
Platform:
GPL34388
Series:
GSE264021
Download data: BED
Sample
Accession:
GSM8208880
ID:
308208880

SRA Run Selector

5.

ATAC WT, donor3

Organism:
Mustela putorius furo
Source name:
Polarized pancreatic ductal epithelia
Platform:
GPL34388
Series:
GSE264021
Download data: BED
Sample
Accession:
GSM8208879
ID:
308208879

SRA Run Selector

6.

ATAC WT, donor2

Organism:
Mustela putorius furo
Source name:
Polarized pancreatic ductal epithelia
Platform:
GPL34388
Series:
GSE264021
Download data: BED
Sample
Accession:
GSM8208878
ID:
308208878

SRA Run Selector

7.

ATAC WT, donor1

Organism:
Mustela putorius furo
Source name:
Polarized pancreatic ductal epithelia
Platform:
GPL34388
Series:
GSE264021
Download data: BED
Sample
Accession:
GSM8208877
ID:
308208877

SRA Run Selector

8.

ATAC CFTRKO knockout, donor3

Organism:
Mustela putorius furo
Source name:
Polarized pancreatic ductal epithelia
Platform:
GPL34388
Series:
GSE264021
Download data: BED
Sample
Accession:
GSM8208876
ID:
308208876

SRA Run Selector

9.

ATAC CFTRKO knockout, donor2

Organism:
Mustela putorius furo
Source name:
Polarized pancreatic ductal epithelia
Platform:
GPL34388
Series:
GSE264021
Download data: BED
Sample
Accession:
GSM8208875
ID:
308208875

SRA Run Selector

10.

ATAC CFTRKO knockout, donor1

Organism:
Mustela putorius furo
Source name:
Polarized pancreatic ductal epithelia
Platform:
GPL34388
Series:
GSE264021
Download data: BED
Sample
Accession:
GSM8208874
ID:
308208874

SRA Run Selector

11.

WT, donor3

Organism:
Mustela putorius furo
Source name:
Polarized pancreatic ductal epithelia
Platform:
GPL34388
Series:
GSE264019
Download data
Sample
Accession:
GSM8208871
ID:
308208871

SRA Run Selector

12.

WT, donor2

Organism:
Mustela putorius furo
Source name:
Polarized pancreatic ductal epithelia
Platform:
GPL34388
Series:
GSE264019
Download data
Sample
Accession:
GSM8208870
ID:
308208870

SRA Run Selector

13.

WT, donor1

Organism:
Mustela putorius furo
Source name:
Polarized pancreatic ductal epithelia
Platform:
GPL34388
Series:
GSE264019
Download data
Sample
Accession:
GSM8208869
ID:
308208869

SRA Run Selector

14.

CFTRKO knockout, donor3

Organism:
Mustela putorius furo
Source name:
Polarized pancreatic ductal epithelia
Platform:
GPL34388
Series:
GSE264019
Download data
Sample
Accession:
GSM8208868
ID:
308208868

SRA Run Selector

15.

CFTRKO knockout, donor2

Organism:
Mustela putorius furo
Source name:
Polarized pancreatic ductal epithelia
Platform:
GPL34388
Series:
GSE264019
Download data
Sample
Accession:
GSM8208867
ID:
308208867

SRA Run Selector

16.

CFTRKO knockout, donor1

Organism:
Mustela putorius furo
Source name:
Polarized pancreatic ductal epithelia
Platform:
GPL34388
Series:
GSE264019
Download data
Sample
Accession:
GSM8208866
ID:
308208866

SRA Run Selector

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