GEO DataSets

(Submitter supplied) The breast cancer cell line MCF-7 was engineered to overexpress the Twist gene resulting in the MCF-7/Twist cell line. To study which miRNA are regulated by Twist, we employed whole genome microarray expression profiling and compared miRNA expression between MCF-7/Twist and MCF-7 cells.

Organism:

Homo sapiens

Type:

Non-coding RNA profiling by array

Platform:

GPL9081

4 Samples

Download data: TXT

(Submitter supplied) Circulating plasma miRNAs profiling in platelets-free plasma samples from Behçet's disease patients compared with healthy subjects, aimed to both pathogenesis elucidation and candidate non-invasive biomarkers identification.

Organism:

Homo sapiens

Type:

Non-coding RNA profiling by array

Platform:

GPL9081

34 Samples

Download data: TXT

(Submitter supplied) Peripheral T cell lymphoma (PTCL) is a very aggressive disease which currently lacks efficient targeted therapy. New therapeutic strategies are needed to improve the very poor outcome of these patients. However, little is known about the molecular pathogenesis of this disease. In this study, we performed a miRNAs expression profiling analysis of a series of 26 PTCL cases in order to find deregulated pathways or genes that could become therapeutic agents for PTCL patients.

Organism:

Homo sapiens

Type:

Non-coding RNA profiling by array

Platforms:

GPL8227 GPL9081

30 Samples

Download data: TXT

(Submitter supplied) To identify if platelet activation would result in altered platelet miRNA profile, not only in total RNA sample, also in AGO2-immunoprecipitation(AGO2-IP) products. To determinate if altered platelet miRNAs could regulate de novo protein synthesis of angiogenic factors in activated platelets, and even more importantly, if miRNA-regulated platelet angiogenic factor synthesis could result in changes of platelet angiogenic activities.

Organism:

Homo sapiens

Type:

Non-coding RNA profiling by array

Platforms:

GPL16541 GPL9081

9 Samples

Download data: TXT, XLS

(Submitter supplied) MicroRNA Analysis of TCGA GBM samples using Agilent MicroRNA array

Organism:

Homo sapiens

Type:

Non-coding RNA profiling by array

Platform:

GPL9081

525 Samples

Download data: TXT

(Submitter supplied) MicroRNA expression levels were assessed during the pseudoglandular phase of normal fetal lung development at the critical time, when the the conducting airways are formed. Precise miRNA regulation is important for proper pulmonary organogenesis, supporting the delicate balance between expansion of progenitor cells and their terminal differentiation. Microarray analyses could indicate the potential involvement of miRNAs important for human pulmonary hypoplasia.

Organism:

Homo sapiens

Type:

Non-coding RNA profiling by array

Platform:

GPL9081

2 Samples

Download data: TXT

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Homo sapiens

Type:

Non-coding RNA profiling by array

Platforms:

GPL8227 GPL9081

4 Samples

Download data: TXT

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Homo sapiens

Type:

Non-coding RNA profiling by array; Expression profiling by array

Platforms:

GPL9081 GPL4133

45 Samples

Download data: TXT

(Submitter supplied) To identify differentially expressed human and viral miRNAs across a panel of B-cell lines, including several primary effusion lymphomas (PEL). Gammaherpesvirus and host cell microRNAs (miRNAs) together modulate gene expression in normal and malignant cells. Using microRNA microarrays, we determined the expression of mature viral and host cellular miRNAs in a series of B cell tumours that include Kaposi’s Sarcoma-associated herpesvirus (KSHV) infected Primary Effusion Lymphoma (PEL) and Epstein-Barr virus (EBV) infected Burkitt’s lymphoma (BL) cell lines. more...

Organism:

Homo sapiens

Type:

Non-coding RNA profiling by array

Platform:

GPL9081

25 Samples

Download data: TXT

(Submitter supplied) miRNA expression in early stage mouse model of dilated cardiomyopathy Apoptosis is a hallmark of multiple etiologies of heart failure, including dilated cardiomyopathy. Since microRNAs are master regulators of cardiac development and key effectors of intracellular signaling, they represent novel candidates for understanding the mechanisms driving the increased dysfunction and loss of cardiomyocytes during cardiovascular disease progression. more...

Organism:

Mus musculus; Homo sapiens

Type:

Non-coding RNA profiling by array

Platforms:

GPL19022 GPL9081

21 Samples

Download data: TXT

(Submitter supplied) 147 B-cell lymphomas were studies for miRNA expression miRNA profiling of control human B cell populations Comparison of miRNA expression profiles of naive B cells (CD19+ IgD+ CD27-) from 3 individuals and germinal center B cells (CD10+ CD19+) from 4 individuals

Organism:

Homo sapiens

Type:

Non-coding RNA profiling by array

Platform:

GPL9081

154 Samples

Download data: TXT

(Submitter supplied) miRNA expression was investigated in ATLL samples and in normal CD4 T-cells (resting and in vitro-stimulated).

Organism:

Homo sapiens

Type:

Non-coding RNA profiling by array

Platform:

GPL9081

15 Samples

Download data: TXT

(Submitter supplied) MicroRNA (miRNA) is a type of non-coding RNA that regulates the expression of its target genes by interacting with the complementary sequence of the target mRNA molecules. Recent evidence has shown that genotoxic stress induces miRNA expression, but the target genes involved and role in cellular responses remain unclear. We examined the role of miRNA in the cellular response to X-ray irradiation by studying the expression profiles of radio-responsive miRNAs and their target genes in cultured human cell lines. more...

Organism:

Homo sapiens

Type:

Non-coding RNA profiling by array; Expression profiling by array

Platforms:

GPL9081 GPL4133

31 Samples

Download data: TXT

(Submitter supplied) MicroRNA (miRNA) is a type of non-coding RNA that regulates the expression of its target genes by interacting with the complementary sequence of the target mRNA molecules. Recent evidence has shown that genotoxic stress induces miRNA expression, but the target genes involved and role in cellular responses remain unclear. We examined the role of miRNA in the cellular response to X-ray irradiation by studying the expression profiles of radio-responsive miRNAs and their target genes in cultured human cell lines. more...

Organism:

Homo sapiens

Type:

Non-coding RNA profiling by array

Platform:

GPL9081

16 Samples

Download data: TXT

(Submitter supplied) We performed miRNA expression profiling in a series of de novo DLBCLs, transformed DLBCLs and non-neoplastic lymph nodes using a microarray approach. Significant differentially expressed miRNAs among groups were identified using SAM analysis.

Organism:

Homo sapiens

Type:

Non-coding RNA profiling by array

Platform:

GPL9081

55 Samples

Download data: TXT

(Submitter supplied) Currently, multiple myeloma (MM) patients are broadly grouped into a non-hyperdiploid Group (nh-MM), highly enriched for IgH translocations, or into a hyperdiploid Group (h-MM), which is typically characterized by trisomies of some odd-numbered chromosomes. We compared the miRNA expression profiles of these two groups and we identified 16 miRNAs that were downregulated in the h-MM group, relative to the nh-MM group. more...

Organism:

Homo sapiens

Type:

Non-coding RNA profiling by array

Platform:

GPL9081

61 Samples

Download data: TXT

(Submitter supplied) Background/Objective: MicroRNAs (miRNAs) play a pivotal role in cancerogenesis and cancer progression, but their specific role in metastasis of clear cell renal cell carcinomas (ccRCCs) as so-called metastamirs is still limited. Based on microRNA microarray analyses from normal (n=12) and cancerous (n=12) samples of ccRCC specimens and from bone metastases (n=9) of ccRCC patients, we identified a set of 57 differentially expressed microRNAs between those three sample groups of ccRCC. more...

Organism:

Homo sapiens

Type:

Non-coding RNA profiling by array

Platform:

GPL9081

40 Samples

Download data: TXT

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Homo sapiens

Type:

Expression profiling by array; Non-coding RNA profiling by array; Methylation profiling by array; Genome variation profiling by SNP array; SNP genotyping by SNP array

6 related Platforms

354 Samples

Download data: CEL, TXT

(Submitter supplied) MicroRNA profiling was performed on RNA samples matched to those included in the NIH Human Pluripotent Stem Cell Database (Series GSE32923). Twenty undifferentiated human embryonic stem cell lines and 4 human tissues were analyzed. Expanded descriptions of methods used are available at: http://stemcelldb.nih.gov.

Organism:

Homo sapiens

Type:

Non-coding RNA profiling by array

Platform:

GPL9081

49 Samples

Download data: TXT

(Submitter supplied) Epidermal growth factor (EGF) stimulates cells by launching gene expression programs that are frequently deregulated in cancer. MicroRNAs, which attenuate gene expression by binding complementary regions in messenger RNAs, are broadly implicated in cancer. Using genome-wide approaches, we showed that EGF stimulation initiates a coordinated transcriptional program of microRNAs and transcription factors. more...

Organism:

Homo sapiens

Type:

Non-coding RNA profiling by array

Platform:

GPL9081

24 Samples

Download data: TXT