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Items: 4

1.

Catalytic subunits switch drives resistance to EZH2 inhibitors in ARID1A-mutated cells [ChIP-seq]

(Submitter supplied) The SWI/SNF chromatin remodeling complex is altered in ~20% of human cancers. ARID1A, a component of the SWI/SNF chromatin-remodeling complex, is the most frequently mutated epigenetic regulator in human cancers. Inactivation of the SWI/SNF complex is synthetically lethal with inhibition of EZH2 activity. EZH2 inhibitors are entering clinical trials for specific tumor types with SWI/SNF mutations. more...
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL18573
2 Samples
Download data: TXT
Series
Accession:
GSE110448
ID:
200110448
2.

Illumina NextSeq 500 (Homo sapiens)

Platform
Accession:
GPL18573
ID:
100018573
3.

BRG1 binding in resistant clone 3 of TOV21G cell line

Organism:
Homo sapiens
Source name:
resistant TOV21G cell line
Platform:
GPL18573
Series:
GSE110448 GSE110450
Download data: TXT
Sample
Accession:
GSM2991372
ID:
302991372
4.

BRG1 binding in parental TOV21G cell line

Organism:
Homo sapiens
Source name:
TOV21G cell line
Platform:
GPL18573
Series:
GSE110448 GSE110450
Download data: TXT
Sample
Accession:
GSM2991371
ID:
302991371
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Supplemental Content

db=gds|term=GSE110448[Accession]|query=1|qty=2|blobid=MCID_674d23e9f363504c2f3b6e80|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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