GSE125032[Accession] - GEO DataSets

Select item 2001250321.

Caliban regulates mitochondrial morphology and redox state in enterocytes to maintain intestinal homeostasis in Drosophila

(Submitter supplied) Precise regulation of stem cell activity is crucial for tissue homeostasis. In Drosophila, intestinal stem cells (ISCs) maintain the midgut epithelium and respond to oxidative challenges by increasing proliferation rates. However, the connection between intestinal homeostasis and redox signaling remains obscure. Here we identify Caliban (Clbn) as a novel mitochondrial protein involved in regulating the cellular redox state in enterocytes (ECs) and the proliferative activity of ISCs. more...

Organism:: Drosophila melanogaster

Type:: Expression profiling by array

Platform:: GPL1322
6 Samples

Download data: CEL

Series

Accession:: GSE125032

ID:: 200125032

Analyze with GEO2R

Select item 1000013222.

[Drosophila_2] Affymetrix Drosophila Genome 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 08, 2012: annotation table updated with netaffx build 32 July 06, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site The GeneChip Drosophila Genome 2.0 Array is a microarray tool for studying expression of Drosophila melanogaster transcripts: - Provides comprehensive coverage of the transcribed Drosophila genome on a single array - Comprised of 18,880 probe sets, analyzing over 18,500 transcripts Sequences used in the design of the GeneChip Drosophila Genome 2.0 Array were selected from Flybase version 3.1. more...