GSE130983[Accession] - GEO DataSets - NCBI

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Select item 2001309831.

IL-11 is a therapeutic target in idiopathic pulmonary fibrosis

(Submitter supplied) Idiopathic pulmonary fibrosis (IPF) is a fatal lung disease where invasive pulmonary myofibroblasts secrete collagen and destroy lung integrity. Here we show that IL-11 is upregulated in the lung of IPF patients, associated with disease severity and is secreted from IPF fibroblasts. In vitro, IL-11 stimulates lung fibroblasts to become invasive, ACTA2+ve, collagen secreting myofibroblasts, in an ERK-dependent fashion. more...

Organism:: Homo sapiens; Mus musculus

Type:: Expression profiling by high throughput sequencing

Platforms:: GPL19057 GPL18573
39 Samples

Download data: TXT

Series

Accession:: GSE130983

ID:: 200130983

PubMed Similar studies SRA Run Selector

Select item 1000190572.

Illumina NextSeq 500 (Mus musculus)

Organism:: Mus musculus

10369 Series
297613 Samples

Platform

Accession:: GPL19057

ID:: 100019057

Select item 1000185733.

Illumina NextSeq 500 (Homo sapiens)

Organism:: Homo sapiens

12659 Series
344647 Samples

Platform

Accession:: GPL18573

ID:: 100018573

Select item 3037582644.

Organism:: Mus musculus

Source name:: Lung Fibroblasts

Platform:: GPL19057
Series:: GSE130983

Sample

Accession:: GSM3758264

ID:: 303758264

SRA Run Selector

Select item 3037582635.

Organism:: Mus musculus

Source name:: Lung Fibroblasts

Platform:: GPL19057
Series:: GSE130983

Sample

Accession:: GSM3758263

ID:: 303758263

SRA Run Selector

Select item 3037582626.

Organism:: Mus musculus

Source name:: Lung Fibroblasts

Platform:: GPL19057
Series:: GSE130983

Sample

Accession:: GSM3758262

ID:: 303758262

SRA Run Selector

Select item 3037582617.

Organism:: Mus musculus

Source name:: Lung Fibroblasts

Platform:: GPL19057
Series:: GSE130983

Sample

Accession:: GSM3758261

ID:: 303758261

SRA Run Selector

Select item 3037582608.

Organism:: Mus musculus

Source name:: Lung Fibroblasts

Platform:: GPL19057
Series:: GSE130983

Sample

Accession:: GSM3758260

ID:: 303758260

SRA Run Selector

Select item 3037582599.

Organism:: Mus musculus

Source name:: Lung Fibroblasts

Platform:: GPL19057
Series:: GSE130983

Sample

Accession:: GSM3758259

ID:: 303758259

SRA Run Selector

Select item 30375825810.

Organism:: Mus musculus

Source name:: Lung Fibroblasts

Platform:: GPL19057
Series:: GSE130983

Sample

Accession:: GSM3758258

ID:: 303758258

SRA Run Selector

Select item 30375825711.

Organism:: Mus musculus

Source name:: Lung Fibroblasts

Platform:: GPL19057
Series:: GSE130983

Sample

Accession:: GSM3758257

ID:: 303758257

SRA Run Selector

Select item 30375825612.

Organism:: Mus musculus

Source name:: Lung Fibroblasts

Platform:: GPL19057
Series:: GSE130983

Sample

Accession:: GSM3758256

ID:: 303758256

SRA Run Selector

Select item 30375825513.

Organism:: Mus musculus

Source name:: Lung Fibroblasts

Platform:: GPL19057
Series:: GSE130983

Sample

Accession:: GSM3758255

ID:: 303758255

SRA Run Selector

Select item 30375825414.

Organism:: Mus musculus

Source name:: Lung Fibroblasts

Platform:: GPL19057
Series:: GSE130983

Sample

Accession:: GSM3758254

ID:: 303758254

SRA Run Selector

Select item 30375825315.

Organism:: Mus musculus

Source name:: Lung Fibroblasts

Platform:: GPL19057
Series:: GSE130983

Sample

Accession:: GSM3758253

ID:: 303758253

SRA Run Selector

Select item 30375825216.

Organism:: Mus musculus

Source name:: Lung

Platform:: GPL19057
Series:: GSE130983

Sample

Accession:: GSM3758252

ID:: 303758252

SRA Run Selector

Select item 30375825117.

Organism:: Mus musculus

Source name:: Lung

Platform:: GPL19057
Series:: GSE130983

Sample

Accession:: GSM3758251

ID:: 303758251

SRA Run Selector

Select item 30375825018.

Organism:: Mus musculus

Source name:: Lung

Platform:: GPL19057
Series:: GSE130983

Sample

Accession:: GSM3758250

ID:: 303758250

SRA Run Selector

Select item 30375824919.

Organism:: Mus musculus

Source name:: Lung

Platform:: GPL19057
Series:: GSE130983

Sample

Accession:: GSM3758249

ID:: 303758249

SRA Run Selector

Select item 30375824820.

Organism:: Mus musculus

Source name:: Lung

Platform:: GPL19057
Series:: GSE130983

Sample

Accession:: GSM3758248

ID:: 303758248

SRA Run Selector

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