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Items: 8

1.

Copy Number of an Integron-Encoded Antibiotic Resistance Locus Regulates a Virulence and Opacity Switch in Acinetobacter baumannii AB5075

(Submitter supplied) We describe a novel genetic mechanism  in which tandem amplification of a plasmid-borne integron regulates virulence, opacity variation, and global gene expression by altering levels of a putative small RNA (sRNA) in Acinetobacter baumannii AB5075. Copy number of this amplified locus correlated with the rate of switching between virulent opaque (VIR-O) and avirulent translucent (AV-T) cells. We found that prototypical VIR-O colonies, which exhibit high levels of switching and visible sectoring with AV-T cells by 24 h of growth, encode two copies of this locus. more...
Organism:
Acinetobacter baumannii
Type:
Expression profiling by high throughput sequencing
Platform:
GPL26038
6 Samples
Download data: TXT
Series
Accession:
GSE156206
ID:
200156206
2.

Illumina HiSeq 3000 (Acinetobacter baumannii)

Organism:
Acinetobacter baumannii
3 Series
18 Samples
Download data
Platform
Accession:
GPL26038
ID:
100026038
3.

6_N1_E_GFF

Organism:
Acinetobacter baumannii
Source name:
LB media
Platform:
GPL26038
Series:
GSE156206
Download data
Sample
Accession:
GSM4726735
ID:
304726735
4.

5_AB5075_E_GFF

Organism:
Acinetobacter baumannii
Source name:
LB media
Platform:
GPL26038
Series:
GSE156206
Download data
Sample
Accession:
GSM4726734
ID:
304726734
5.

4_N1_D_GFF

Organism:
Acinetobacter baumannii
Source name:
LB media
Platform:
GPL26038
Series:
GSE156206
Download data
Sample
Accession:
GSM4726733
ID:
304726733
6.

3_AB5075_D_GFF

Organism:
Acinetobacter baumannii
Source name:
LB media
Platform:
GPL26038
Series:
GSE156206
Download data
Sample
Accession:
GSM4726732
ID:
304726732
7.

2_N1_C_GFF

Organism:
Acinetobacter baumannii
Source name:
LB media
Platform:
GPL26038
Series:
GSE156206
Download data
Sample
Accession:
GSM4726731
ID:
304726731
8.

1_AB5075_C_GFF

Organism:
Acinetobacter baumannii
Source name:
LB media
Platform:
GPL26038
Series:
GSE156206
Download data
Sample
Accession:
GSM4726730
ID:
304726730
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Supplemental Content

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