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Items: 8

1.

Differential Ezh1/2 regulation of hemogenic fate and hematopoietic stem and progenitor cell formation from arterial endothelium

(Submitter supplied) Across species, hematopoietic stem and progenitor cells (HSPCs) arise during embryogenesis from a specialized arterial population, termed hemogenic endothelium. Here, we describe a mechanistic role for the epigenetic regulator, Enhancer of zeste homolog-1 (Ezh1) in vertebrate HSPC production via regulation of hemogenic commitment. Loss of ezh1 in zebrafish embryos favored acquisition of hemogenic (gata2b) and HSPC (runx1) fate at the expense of the arterial program (ephrinb2a, dll4). more...
Organism:
Danio rerio
Type:
Expression profiling by high throughput sequencing
Platform:
GPL24995
6 Samples
Download data: MTX, RDS, TSV
Series
Accession:
GSE173972
ID:
200173972

PubMed Full text in PMC Similar studies SRA Run Selector

2.

Illumina NovaSeq 6000 (Danio rerio)

Organism:
Danio rerio
401 Series
6422 Samples
Download data
Platform
Accession:
GPL24995
ID:
100024995

3.

EZH1 KO rep2

Organism:
Danio rerio
Source name:
kdrl:GFP+ cells 30hpf
Platform:
GPL24995
Series:
GSE173972
Download data: MTX, TSV
Sample
Accession:
GSM5283744
ID:
305283744

SRA Run Selector

4.

EZH1 KO rep1

Organism:
Danio rerio
Source name:
kdrl:GFP+ cells 30hpf
Platform:
GPL24995
Series:
GSE173972
Download data: MTX, TSV
Sample
Accession:
GSM5283743
ID:
305283743

SRA Run Selector

5.

EZH1 HET rep2

Organism:
Danio rerio
Source name:
kdrl:GFP+ cells 30hpf
Platform:
GPL24995
Series:
GSE173972
Download data: MTX, TSV
Sample
Accession:
GSM5283742
ID:
305283742

SRA Run Selector

6.

EZH1 HET rep1

Organism:
Danio rerio
Source name:
kdrl:GFP+ cells 30hpf
Platform:
GPL24995
Series:
GSE173972
Download data: MTX, TSV
Sample
Accession:
GSM5283741
ID:
305283741

SRA Run Selector

7.

EZH1 WT rep2

Organism:
Danio rerio
Source name:
kdrl:GFP+ cells 30hpf
Platform:
GPL24995
Series:
GSE173972
Download data: MTX, TSV
Sample
Accession:
GSM5283740
ID:
305283740

SRA Run Selector

8.

EZH1 WT rep1

Organism:
Danio rerio
Source name:
kdrl:GFP+ cells 30hpf
Platform:
GPL24995
Series:
GSE173972
Download data: MTX, TSV
Sample
Accession:
GSM5283739
ID:
305283739

SRA Run Selector

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db=gds|term=GSE173972[Accession]|query=1|qty=2|blobid=MCID_674d2593f363504c2f3ba5e7|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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