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Items: 15

1.

Epigenetic therapy targets the 3D epigenome in endocrine-resistant breast cancer [CUT&RUN]

(Submitter supplied) Here we investigate the impact of epigenetic therapy with Decitabine in endocrine-resistant ER+ breast cancer by using patient-derived xenograft (PDX) models. Decitabine treatment restrained tumour growth, inhibited cell proliferation and resulted in significant loss of DNA methylation, particularly at enhancers and repetitive elements. Systematic integration of matched in situ Hi-C / PCHi-C, EPIC, RNA-seq and ChIP–seq datasets revealed widespread differences in epigenome regulation and enhancer-promoter communication with Decitabine. more...
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL18573
13 Samples
Download data: BED
Series
Accession:
GSE237769
ID:
200237769

PubMed Full text in PMC Similar studies

2.

Illumina NextSeq 500 (Homo sapiens)

Organism:
Homo sapiens
12621 Series
344016 Samples
Download data
Platform
Accession:
GPL18573
ID:
100018573

3.

Gar15-13 IgG

Organism:
Homo sapiens
Source name:
Gar15-13 tumour
Platform:
GPL18573
Series:
GSE171074 GSE237769
Download data
Sample
Accession:
GSM7648692
ID:
307648692

SRA Run Selector

4.

Gar15-13 Decitabine 3 H3K27ac

Organism:
Homo sapiens
Source name:
Gar15-13 Decitabine tumour
Platform:
GPL18573
Series:
GSE171074 GSE237769
Download data: BED
Sample
Accession:
GSM7648691
ID:
307648691

SRA Run Selector

5.

Gar15-13 Decitabine 2 H3K27ac

Organism:
Homo sapiens
Source name:
Gar15-13 Decitabine tumour
Platform:
GPL18573
Series:
GSE171074 GSE237769
Download data: BED
Sample
Accession:
GSM7648690
ID:
307648690

SRA Run Selector

6.

Gar15-13 Decitabine 1 H3K27ac

Organism:
Homo sapiens
Source name:
Gar15-13 Decitabine tumour
Platform:
GPL18573
Series:
GSE171074 GSE237769
Download data: BED
Sample
Accession:
GSM7648689
ID:
307648689

SRA Run Selector

7.

Gar15-13 Vehicle 3 H3K27ac

Organism:
Homo sapiens
Source name:
Gar15-13 Vehicle tumour
Platform:
GPL18573
Series:
GSE171074 GSE237769
Download data: BED
Sample
Accession:
GSM7648688
ID:
307648688

SRA Run Selector

8.

Gar15-13 Vehicle 2 H3K27ac

Organism:
Homo sapiens
Source name:
Gar15-13 Vehicle tumour
Platform:
GPL18573
Series:
GSE171074 GSE237769
Download data: BED
Sample
Accession:
GSM7648687
ID:
307648687

SRA Run Selector

9.

Gar15-13 Vehicle 1 H3K27ac

Organism:
Homo sapiens
Source name:
Gar15-13 Vehicle tumour
Platform:
GPL18573
Series:
GSE171074 GSE237769
Download data: BED
Sample
Accession:
GSM7648686
ID:
307648686

SRA Run Selector

10.

Gar15-13 Decitabine 3 CTCF

Organism:
Homo sapiens
Source name:
Gar15-13 Decitabine tumour
Platform:
GPL18573
Series:
GSE171074 GSE237769
Download data: BED
Sample
Accession:
GSM7648685
ID:
307648685

SRA Run Selector

11.

Gar15-13 Decitabine 2 CTCF

Organism:
Homo sapiens
Source name:
Gar15-13 Decitabine tumour
Platform:
GPL18573
Series:
GSE171074 GSE237769
Download data: BED
Sample
Accession:
GSM7648684
ID:
307648684

SRA Run Selector

12.

Gar15-13 Decitabine 1 CTCF

Organism:
Homo sapiens
Source name:
Gar15-13 Decitabine tumour
Platform:
GPL18573
Series:
GSE171074 GSE237769
Download data: BED
Sample
Accession:
GSM7648683
ID:
307648683

SRA Run Selector

13.

Gar15-13 Vehicle 3 CTCF

Organism:
Homo sapiens
Source name:
Gar15-13 Vehicle tumour
Platform:
GPL18573
Series:
GSE171074 GSE237769
Download data: BED
Sample
Accession:
GSM7648682
ID:
307648682

SRA Run Selector

14.

Gar15-13 Vehicle 2 CTCF

Organism:
Homo sapiens
Source name:
Gar15-13 Vehicle tumour
Platform:
GPL18573
Series:
GSE171074 GSE237769
Download data: BED
Sample
Accession:
GSM7648681
ID:
307648681

SRA Run Selector

15.

Gar15-13 Vehicle 1 CTCF

Organism:
Homo sapiens
Source name:
Gar15-13 Vehicle tumour
Platform:
GPL18573
Series:
GSE171074 GSE237769
Download data: BED
Sample
Accession:
GSM7648680
ID:
307648680

SRA Run Selector

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db=gds|term=GSE237769[Accession]|query=1|qty=2|blobid=MCID_674dc9b38a1e1e27ad1f9730|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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