GSE267862[Accession] - GEO DataSets - NCBI

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Select item 2002678621.

Pseudomonas aeruginosa Activates Quorum Sensing, Antioxidant Enzymes and Type VI Secretion in Response to Oxidative Stress to Initiate Biofilm Formation and Wound Chronicity

(Submitter supplied) Pseudomonas aeruginosa (PA) is an opportunistic pathogen frequently isolated from cutaneous chronic wounds. How PA, in the presence of oxidative stress (OS), colonizes chronic wounds and forms a biofilm is still unknown. The purpose of this study is to investigate the changes in gene expression seen when PA is challenged with the high levels of OS present in chronic wounds. We used a biofilm-forming PA strain isolated from the chronic wounds of our murine model (RPA) and performed a qPCR to obtain gene expression patterns as RPA developed a biofilm in vitro in the presence of high levels of OS, and then compared the findings in vivo, in our mouse model of chronic wounds. more...

Organism:: Pseudomonas aeruginosa

Type:: Expression profiling by high throughput sequencing

Platform:: GPL33271
18 Samples

Download data: TXT

Series

Accession:: GSE267862

ID:: 200267862

PubMed Full text in PMC Similar studies

Select item 1000332712.

NextSeq 2000 (Pseudomonas aeruginosa)

Organism:: Pseudomonas aeruginosa

6 Series
45 Samples

Platform

Accession:: GPL33271

ID:: 100033271

Select item 3082799913.

Organism:: Pseudomonas aeruginosa

Source name:: nonchronic wound

Platform:: GPL33271
Series:: GSE267862

Sample

Accession:: GSM8279991

ID:: 308279991

SRA Run Selector

Select item 3082799904.

Organism:: Pseudomonas aeruginosa

Source name:: nonchronic wound

Platform:: GPL33271
Series:: GSE267862

Sample

Accession:: GSM8279990

ID:: 308279990

SRA Run Selector

Select item 3082799895.

Organism:: Pseudomonas aeruginosa

Source name:: nonchronic wound

Platform:: GPL33271
Series:: GSE267862

Sample

Accession:: GSM8279989

ID:: 308279989

SRA Run Selector

Select item 3082799886.

Organism:: Pseudomonas aeruginosa

Source name:: nonchronic wound

Platform:: GPL33271
Series:: GSE267862

Sample

Accession:: GSM8279988

ID:: 308279988

SRA Run Selector

Select item 3082799877.

Organism:: Pseudomonas aeruginosa

Source name:: nonchronic wound

Platform:: GPL33271
Series:: GSE267862

Sample

Accession:: GSM8279987

ID:: 308279987

SRA Run Selector

Select item 3082799868.

Organism:: Pseudomonas aeruginosa

Source name:: nonchronic wound

Platform:: GPL33271
Series:: GSE267862

Sample

Accession:: GSM8279986

ID:: 308279986

SRA Run Selector

Select item 3082799859.

Organism:: Pseudomonas aeruginosa

Source name:: nonchronic wound

Platform:: GPL33271
Series:: GSE267862

Sample

Accession:: GSM8279985

ID:: 308279985

SRA Run Selector

Select item 30827998410.

Organism:: Pseudomonas aeruginosa

Source name:: nonchronic wound

Platform:: GPL33271
Series:: GSE267862

Sample

Accession:: GSM8279984

ID:: 308279984

SRA Run Selector

Select item 30827998311.

Organism:: Pseudomonas aeruginosa

Source name:: nonchronic wound

Platform:: GPL33271
Series:: GSE267862

Sample

Accession:: GSM8279983

ID:: 308279983

SRA Run Selector

Select item 30827998212.

Organism:: Pseudomonas aeruginosa

Source name:: chronic wound

Platform:: GPL33271
Series:: GSE267862

Sample

Accession:: GSM8279982

ID:: 308279982

SRA Run Selector

Select item 30827998113.

Organism:: Pseudomonas aeruginosa

Source name:: chronic wound

Platform:: GPL33271
Series:: GSE267862

Sample

Accession:: GSM8279981

ID:: 308279981

SRA Run Selector

Select item 30827998014.

Organism:: Pseudomonas aeruginosa

Source name:: chronic wound

Platform:: GPL33271
Series:: GSE267862

Sample

Accession:: GSM8279980

ID:: 308279980

SRA Run Selector

Select item 30827997915.

Organism:: Pseudomonas aeruginosa

Source name:: chronic wound

Platform:: GPL33271
Series:: GSE267862

Sample

Accession:: GSM8279979

ID:: 308279979

SRA Run Selector

Select item 30827997816.

Organism:: Pseudomonas aeruginosa

Source name:: chronic wound

Platform:: GPL33271
Series:: GSE267862

Sample

Accession:: GSM8279978

ID:: 308279978

SRA Run Selector

Select item 30827997717.

Organism:: Pseudomonas aeruginosa

Source name:: chronic wound

Platform:: GPL33271
Series:: GSE267862

Sample

Accession:: GSM8279977

ID:: 308279977

SRA Run Selector

Select item 30827997618.

Organism:: Pseudomonas aeruginosa

Source name:: chronic wound

Platform:: GPL33271
Series:: GSE267862

Sample

Accession:: GSM8279976

ID:: 308279976

SRA Run Selector

Select item 30827997519.

Organism:: Pseudomonas aeruginosa

Source name:: chronic wound

Platform:: GPL33271
Series:: GSE267862

Sample

Accession:: GSM8279975

ID:: 308279975

SRA Run Selector

Select item 30827997420.

Organism:: Pseudomonas aeruginosa

Source name:: chronic wound

Platform:: GPL33271
Series:: GSE267862

Sample

Accession:: GSM8279974

ID:: 308279974

SRA Run Selector

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