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Items: 5

1.

Polarized Dock Activity Drives Shh-Mediated Axon Guidance

(Submitter supplied) In the developing spinal cord, Sonic hedgehog (Shh) attracts commissural axons toward the floor plate. How Shh regulates the cytoskeletal remodeling that underlies growth cone turning is unknown. We found that Shh-mediated growth cone turning requires the activity of Docks, which are unconventional GEFs. Knockdown of Dock3 and 4, or their binding partner ELMO1 and 2, abolished commissural axon attraction by Shh in vitro. more...
Organism:
Rattus norvegicus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL14844
3 Samples
Download data: CSV
Series
Accession:
GSE268644
ID:
200268644

PubMed Similar studies

2.

Illumina HiSeq 2000 (Rattus norvegicus)

Organism:
Rattus norvegicus
333 Series
6659 Samples
Download data
Platform
Accession:
GPL14844
ID:
100014844

3.

commissural neurons, rep 3

Organism:
Rattus norvegicus
Source name:
spinal cord
Platform:
GPL14844
Series:
GSE268644
Download data
Sample
Accession:
GSM8295848
ID:
308295848

SRA Run Selector

4.

commissural neurons, rep 2

Organism:
Rattus norvegicus
Source name:
spinal cord
Platform:
GPL14844
Series:
GSE268644
Download data
Sample
Accession:
GSM8295847
ID:
308295847

SRA Run Selector

5.

commissural neurons, rep 1

Organism:
Rattus norvegicus
Source name:
spinal cord
Platform:
GPL14844
Series:
GSE268644
Download data
Sample
Accession:
GSM8295846
ID:
308295846

SRA Run Selector

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