GSE274995[Accession] - GEO DataSets - NCBI

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Items: 5

Select item 2002749951.

Super-enhancer driven LIF/LIFR-STAT3-SOX2 regulatory feedback loop promotes cancer stemness in head and neck squamous cell carcinoma (ChIP-seq)

(Submitter supplied) Super-enhancers (SEs) have been recognized as key epigenetic regulators underlying cancer stemness and malignant traits by aberrant transcriptional control and promising therapeutic targets against human cancers. However, the SE landscape and their roles during head and neck squamous cell carcinoma (HNSCC) development especially in cancer stem cells (CSCs) maintenance remain underexplored yet. Here, we identified leukemia inhibitory factor (LIF)-SE as a representative oncogenic SE to activate LIF transcription in HNSCC. more...

Organism:: Homo sapiens

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL24676
3 Samples

Download data: BW, NARROWPEAK

Series

Accession:: GSE274995

ID:: 200274995

Select item 1000246762.

Illumina NovaSeq 6000 (Homo sapiens)

Organism:: Homo sapiens

18321 Series
955298 Samples

Platform

Accession:: GPL24676

ID:: 100024676

Select item 3084640663.

Organism:: Homo sapiens

Source name:: Cal27

Platform:: GPL24676
Series:: GSE274995

Download data: BW

Sample

Accession:: GSM8464066

ID:: 308464066

SRA Run Selector

Select item 3084640654.

Cal27, p300, ChIP

Organism:: Homo sapiens

Source name:: Cal27

Platform:: GPL24676
Series:: GSE274995

Download data: BW, NARROWPEAK

Sample

Accession:: GSM8464065

ID:: 308464065

SRA Run Selector

Select item 3084640645.

Cal27, BRD4, ChIP

Organism:: Homo sapiens

Source name:: Cal27

Platform:: GPL24676
Series:: GSE274995

Download data: BW, NARROWPEAK

Sample

Accession:: GSM8464064

ID:: 308464064

SRA Run Selector

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GSE274995[Accession] (5)
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