GSE31059[Accession] - GEO DataSets - NCBI

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Items: 14

Select item 2000310591.

Gene expression profiling of L-540 Hodgkin lymphoma cell line after in vitro and in vivo treatment with perifosine in combination with sorafenib

(Submitter supplied) Three HL cell lines (HD-MyZ, L-540 and HDLM-2) were used to investigate the effects of perifosine and sorafenib using in vitro assays analyzing cell growth, cell cycle distribution, gene expression profiling (GEP), and apoptosis. Western blotting (WB) experiments were performed to determine whether the two-drug combination affected MAPK and PI3K/AKT pathways as well as apoptosis. Additionally, the antitumor efficacy and mechanism of action of perifosine/sorafenib combination were investigated in vivo in nonobese diabetic/severe combined immunodeficient (NOD/SCID) mice using tumor growth rates and survival as endpoints. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL6947
12 Samples

Download data: TXT

Series

Accession:: GSE31059

ID:: 200031059

PubMed Similar studies Analyze with GEO2R

Select item 1000069472.

Illumina HumanHT-12 V3.0 expression beadchip

(Submitter supplied) The HumanHT-12 V3.0 Expression BeadChip features up-to-date content derived from the National Center for Biotechnology Information Reference Sequence (NCBI RefSeq) database (Build 36.2, Release 22). Please use the GEO Data Submission Report Plug-in v1.0 for Gene Expression which may be downloaded from https://icom.illumina.com/icom/software.ilmn?id=234 to format the normalized and raw data. These should be submitted as part of a GEOarchive. more...

Organism:: Homo sapiens

13 DataSets
542 Series
1 Related Platform
26115 Samples

Download data: BGX

Platform

Accession:: GPL6947

ID:: 100006947

Select item 3007692713.

L-540_Perifosine 10µM+Sorafenib 5µM_24hrs_4C

Organism:: Homo sapiens

Source name:: L-540_Perifosine 10µM+Sorafenib 5µM_24hrs

Platform:: GPL6947
Series:: GSE31059 GSE31060

Sample

Accession:: GSM769271

ID:: 300769271

Select item 3007692704.

L-540_Perifosine 10µM+Sorafenib 5µM_24hrs_4B

Organism:: Homo sapiens

Source name:: L-540_Perifosine 10µM+Sorafenib 5µM_24hrs

Platform:: GPL6947
Series:: GSE31059 GSE31060

Sample

Accession:: GSM769270

ID:: 300769270

Select item 3007692695.

L-540_Perifosine 10µM+Sorafenib 5µM_24hrs_4A

Organism:: Homo sapiens

Source name:: L-540_Perifosine 10µM+Sorafenib 5µM_24hrs

Platform:: GPL6947
Series:: GSE31059 GSE31060

Sample

Accession:: GSM769269

ID:: 300769269

Select item 3007692686.

L-540_Sorafenib 5µM_24hrs_3C

Organism:: Homo sapiens

Source name:: L-540_Sorafenib 5µM_24hrs

Platform:: GPL6947
Series:: GSE31059 GSE31060

Sample

Accession:: GSM769268

ID:: 300769268

Select item 3007692677.

L-540_Sorafenib 5µM_24hrs_3B

Organism:: Homo sapiens

Source name:: L-540_Sorafenib 5µM_24hrs

Platform:: GPL6947
Series:: GSE31059 GSE31060

Sample

Accession:: GSM769267

ID:: 300769267

Select item 3007692668.

L-540_Sorafenib 5µM_24hrs_3A

Organism:: Homo sapiens

Source name:: L-540_Sorafenib 5µM_24hrs

Platform:: GPL6947
Series:: GSE31059 GSE31060

Sample

Accession:: GSM769266

ID:: 300769266

Select item 3007692659.

L-540_Perifosine 10µM_24hrs_2C

Organism:: Homo sapiens

Source name:: L-540_Perifosine 10µM_24hrs

Platform:: GPL6947
Series:: GSE31059 GSE31060

Sample

Accession:: GSM769265

ID:: 300769265

Select item 30076926410.

L-540_Perifosine 10µM_24hrs_2B

Organism:: Homo sapiens

Source name:: L-540_Perifosine 10µM_24hrs

Platform:: GPL6947
Series:: GSE31059 GSE31060

Sample

Accession:: GSM769264

ID:: 300769264

Select item 30076926311.

L-540_Perifosine 10µM_24hrs_2A

Organism:: Homo sapiens

Source name:: L-540_Perifosine 10µM_24hrs

Platform:: GPL6947
Series:: GSE31059 GSE31060

Sample

Accession:: GSM769263

ID:: 300769263

Select item 30076926212.

L-540_CTRL_24hrs_1C

Organism:: Homo sapiens

Source name:: L-540_CTRL_24hrs

Platform:: GPL6947
Series:: GSE31059 GSE31060

Sample

Accession:: GSM769262

ID:: 300769262

Select item 30076926113.

L-540_CTRL_24hrs_1B

Organism:: Homo sapiens

Source name:: L-540_CTRL_24hrs

Platform:: GPL6947
Series:: GSE31059 GSE31060

Sample

Accession:: GSM769261

ID:: 300769261

Select item 30076926014.

L-540_CTRL_24hrs_1A

Organism:: Homo sapiens

Source name:: L-540_CTRL_24hrs

Platform:: GPL6947
Series:: GSE31059 GSE31060

Sample

Accession:: GSM769260

ID:: 300769260

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