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Items: 11

1.

Somatic cell fusions reveal extensive heterogeneity in basal-like breast cancer [methylation27]

(Submitter supplied) Basal-like and luminal breast tumors have distinct clinical behavior and molecular profiles, yet the underlying mechanisms are poorly defined. To interrogate processes that determine these distinct phenotypes and their inheritance pattern, we generated somatic cell fusions and performed integrated genetic and epigenetic (DNA methylation and chromatin) profiling. We found that the basal-like trait is generally dominant and it is largely defined by epigenetic repression of luminal transcription factors. more...
Organism:
Homo sapiens
Type:
Methylation profiling by array
Platform:
GPL8490
9 Samples
Download data: TXT
Series
Accession:
GSE38791
ID:
200038791
2.

Illumina HumanMethylation27 BeadChip (HumanMethylation27_270596_v.1.2)

(Submitter supplied) HumanMethylation27 DNA Analysis BeadChip allows researchers to interrogate 27,578 highly informative CpG sites per sample at single-nucleotide resolution. This 12-sample BeadChip features content derived from the well-annotated NCBI CCDS database (Genome Build 36) and is supplemented with more than 1,000 cancer-related genes described in published literature. Probe content has been enriched to deeply cover more than 150 well-established cancer genes known to show differential methylation patterns. more...
Organism:
Homo sapiens
348 Series
19058 Samples
Download data: CSV
Platform
Accession:
GPL8490
ID:
100008490
3.

SUM159PT_BT474_AVG_Beta

Organism:
Homo sapiens
Source name:
breast cancer cell lines
Platform:
GPL8490
Series:
GSE38548 GSE38791
Download data
Sample
Accession:
GSM949600
ID:
300949600
4.

BT474_AVG_Beta

Organism:
Homo sapiens
Source name:
breast cancer cell lines
Platform:
GPL8490
Series:
GSE38548 GSE38791
Download data
Sample
Accession:
GSM949599
ID:
300949599
5.

MDAMB231_AVG_Beta

Organism:
Homo sapiens
Source name:
breast cancer cell lines
Platform:
GPL8490
Series:
GSE38548 GSE38791
Download data
Sample
Accession:
GSM949598
ID:
300949598
6.

MCF7_H3K27me3_AVG_Beta

Organism:
Homo sapiens
Source name:
breast cancer cell lines
Platform:
GPL8490
Series:
GSE38548 GSE38791
Download data
Sample
Accession:
GSM949597
ID:
300949597
7.

T47D_H3K27me3_AVG_Beta

Organism:
Homo sapiens
Source name:
breast cancer cell lines
Platform:
GPL8490
Series:
GSE38548 GSE38791
Download data
Sample
Accession:
GSM949596
ID:
300949596
8.

MDAMB231_MCF7_AVG_Beta

Organism:
Homo sapiens
Source name:
breast cancer cell lines
Platform:
GPL8490
Series:
GSE38548 GSE38791
Download data
Sample
Accession:
GSM949595
ID:
300949595
9.

SUM159PT_MCF7_AVG_Beta

Organism:
Homo sapiens
Source name:
breast cancer cell lines
Platform:
GPL8490
Series:
GSE38548 GSE38791
Download data
Sample
Accession:
GSM949594
ID:
300949594
10.

SUM159PT_T47D_AVG_Beta

Organism:
Homo sapiens
Source name:
breast cancer cell lines
Platform:
GPL8490
Series:
GSE38548 GSE38791
Download data
Sample
Accession:
GSM949593
ID:
300949593
11.

SUM159PT_AVG_Beta

Organism:
Homo sapiens
Source name:
breast cancer cell lines
Platform:
GPL8490
Series:
GSE38548 GSE38791
Download data
Sample
Accession:
GSM949592
ID:
300949592
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Supplemental Content

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