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Items: 7

1.

DNA Topoisomerase 1a Promotes RNA-directed DNA Methylation and Histone Lysine 9 Dimethylation at Transposable Elements in Arabidopsis [RNA-Seq]

(Submitter supplied) RNA-directed DNA methylation (RdDM) is a transcriptional silencing mechanism mediated by small and long noncoding RNAs produced by the plant-specific RNA polymerases Pol IV and Pol V, respectively. Through a chemical genetics screen with a luciferase-based DNA methylation reporter, LUCL, we found that camptothecin, a compound with anti-cancer properties that targets DNA topoisomerase 1a (TOP1a) was able to de-repress LUCL by reducing its DNA methylation and H3K9 dimethylation (H3K9me2) levels. more...
Organism:
Arabidopsis thaliana
Type:
Non-coding RNA profiling by high throughput sequencing
Platform:
GPL13222
5 Samples
Download data: TXT
Series
Accession:
GSE50719
ID:
200050719
2.

Illumina HiSeq 2000 (Arabidopsis thaliana)

Organism:
Arabidopsis thaliana
786 Series
11130 Samples
Download data
Platform
Accession:
GPL13222
ID:
100013222
3.

top1a-2 smallRNAseq

Organism:
Arabidopsis thaliana
Source name:
top1a-2 smallRNAseq
Platform:
GPL13222
Series:
GSE50719 GSE50720
Download data: TXT
Sample
Accession:
GSM1227192
ID:
301227192
4.

Ler smallRNAseq

Organism:
Arabidopsis thaliana
Source name:
Ler smallRNAseq
Platform:
GPL13222
Series:
GSE50719 GSE50720
Download data: TXT
Sample
Accession:
GSM1227191
ID:
301227191
5.

nrpe1-11 smallRNAseq

Organism:
Arabidopsis thaliana
Source name:
nrpe1-11 smallRNAseq
Platform:
GPL13222
Series:
GSE50719 GSE50720
Download data: TXT
Sample
Accession:
GSM1227190
ID:
301227190
6.

sde4-3 smallRNAseq

Organism:
Arabidopsis thaliana
Source name:
sde4-3 smallRNAseq
Platform:
GPL13222
Series:
GSE50719 GSE50720
Download data: TXT
Sample
Accession:
GSM1227189
ID:
301227189
7.

Col smallRNAseq

Organism:
Arabidopsis thaliana
Source name:
Col smallRNAseq
Platform:
GPL13222
Series:
GSE50719 GSE50720
Download data: TXT
Sample
Accession:
GSM1227188
ID:
301227188
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Supplemental Content

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