GSE53300[Accession] - GEO DataSets - NCBI

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Items: 4

Select item 2000533001.

Gene expression profiling of breast cancer cells with knockdown of PTEN

(Submitter supplied) Activation of the PI3K pathway in estrogen receptor α (ER)-positive (+) breast cancer is associated with reduced ER expression and activity, luminal B subtype, and poor outcome. PTEN is a negative regulator of the PI3K pathway typically lost in ER-negative (-) breast cancer. To clarify the effect of PTEN down-regulation on the response of ER+/HER2- breast cancer to endocrine therapy, we established reduced PTEN cell models using inducible knockdown. more...

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL9052
2 Samples

Download data: FPKM_TRACKING

Series

Accession:: GSE53300

ID:: 200053300

PubMed Full text in PMC Similar studies Analyze with GEO2R SRA Run Selector

Select item 1000090522.

Illumina Genome Analyzer (Homo sapiens)

Organism:: Homo sapiens

589 Series
7989 Samples

Platform

Accession:: GPL9052

ID:: 100009052

Select item 3012891233.

MCF7L-shPTEN cells with DOX, and reduced PTEN

Organism:: Homo sapiens

Source name:: MCF7L breast cancer cells

Platform:: GPL9052
Series:: GSE53300

Download data: FPKM_TRACKING

Sample

Accession:: GSM1289123

ID:: 301289123

SRA Run Selector

Select item 3012891224.

control MCF7L-shPTEN cells (no DOX, no reduced PTEN)

Organism:: Homo sapiens

Source name:: MCF7L breast cancer cells

Platform:: GPL9052
Series:: GSE53300

Download data: FPKM_TRACKING

Sample

Accession:: GSM1289122

ID:: 301289122

SRA Run Selector

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GSE53300[Accession] (4)
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