GEO DataSets

(Submitter supplied) Despite the high toxicity, alkylating agents are still at the forefront of several clinical protocols used to treat cancers. In this study, we investigated the mechanisms underlying alkylation damage responses, aiming to identify novel strategies to augment alkylating therapy efficacy. In this pursuit, we compared gene expression profiles of evolutionary distant cell types (D. melanogaster Kc167 cells, mouse embryonic fibroblasts and human cancer cells) in response to the alkylating agent methyl-methanesulfonate (MMS). more...

Organism:

Drosophila melanogaster

Type:

Expression profiling by array

Platform:

GPL1322

36 Samples

Download data: CEL

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 08, 2012: annotation table updated with netaffx build 32 July 06, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site The GeneChip Drosophila Genome 2.0 Array is a microarray tool for studying expression of Drosophila melanogaster transcripts: - Provides comprehensive coverage of the transcribed Drosophila genome on a single array - Comprised of 18,880 probe sets, analyzing over 18,500 transcripts Sequences used in the design of the GeneChip Drosophila Genome 2.0 Array were selected from Flybase version 3.1. more...

Organism:

Drosophila melanogaster

25 DataSets

362 Series

1 Related Platform

5224 Samples

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