GEO DataSets

(Submitter supplied) The transcriptional factor ToxR initiates a virulence regulatory cascade required for V. cholerae to express critical host colonization factors and cause disease. Genome-wide expression studies suggest that ToxR regulates many genes important for V. cholerae pathogenesis, yet our knowledge of the direct regulon controlled by ToxR is limited to just four genes. Here, we determine ToxR’s genome-wide DNA-binding profile and show that ToxR is a global regulator of both progenitor genome-encoded genes and horizontally acquired islands encoding the majority of V. more...

Organism:

Vibrio cholerae O1 str. C6706

Type:

Genome binding/occupancy profiling by high throughput sequencing

Platform:

GPL15333

3 Samples

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