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Items: 19

1.

Epigenetic Profile in Transcription elongation factors are in vivo-specific cancer dependencies in glioma

(Submitter supplied) Glioblastoma ranks as one of the most lethal human cancers, with no effective therapies. To discover novel therapeutic targets, here we performed parallel in vivo and in vitro RNA interference screens of epigenetic regulators and show that transcription elongation factors are essential for human glioblastoma cell survival in vivo, but not in vitro. Context-specific dependency in vivo is driven by microenvironment-induced global changes in the cancer epigenome. more...
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL18573
17 Samples
Download data: BED, BIGWIG, TDF
Series
Accession:
GSE74520
ID:
200074520

PubMed Full text in PMC Similar studies SRA Run Selector

2.

Illumina NextSeq 500 (Homo sapiens)

Organism:
Homo sapiens
12602 Series
343758 Samples
Download data
Platform
Accession:
GPL18573
ID:
100018573

3.

IN528_culture_pol2

Organism:
Homo sapiens
Source name:
Primary Patient Derived Tumor Model
Platform:
GPL18573
Series:
GSE74520 GSE74529
Download data: BIGWIG
Sample
Accession:
GSM2360998
ID:
302360998

SRA Run Selector

4.

IN528_IC_pol2

Organism:
Homo sapiens
Source name:
Primary Patient Derived Tumor Model
Platform:
GPL18573
Series:
GSE74520 GSE74529
Download data: BIGWIG
Sample
Accession:
GSM2360997
ID:
302360997

SRA Run Selector

5.

IN528_IC_pol2 input

Organism:
Homo sapiens
Source name:
Primary Patient Derived Tumor Model
Platform:
GPL18573
Series:
GSE74520 GSE74529
Download data
Sample
Accession:
GSM2360996
ID:
302360996

SRA Run Selector

6.

3565_culture_pol2

Organism:
Homo sapiens
Source name:
Primary Patient Derived Tumor Model
Platform:
GPL18573
Series:
GSE74520 GSE74529
Download data: BIGWIG
Sample
Accession:
GSM2360995
ID:
302360995

SRA Run Selector

7.

3565culture_JMJD6

Organism:
Homo sapiens
Source name:
Primary Patient Derived Tumor Model
Platform:
GPL18573
Series:
GSE74520 GSE74529
Download data: BED, TDF
Sample
Accession:
GSM2360994
ID:
302360994

SRA Run Selector

8.

3565culture_H3K27Ac

Organism:
Homo sapiens
Source name:
Primary Patient Derived Tumor Model
Platform:
GPL18573
Series:
GSE74520 GSE74529
Download data: BED, TDF
Sample
Accession:
GSM2360993
ID:
302360993

SRA Run Selector

9.

3565culture_H3K27Ac input

Organism:
Homo sapiens
Source name:
Primary Patient Derived Tumor Model
Platform:
GPL18573
Series:
GSE74520 GSE74529
Download data
Sample
Accession:
GSM2360992
ID:
302360992

SRA Run Selector

10.

3565_IC_pol2

Organism:
Homo sapiens
Source name:
Primary Patient Derived Tumor Model
Platform:
GPL18573
Series:
GSE74520 GSE74529
Download data: BIGWIG
Sample
Accession:
GSM2360991
ID:
302360991

SRA Run Selector

11.

3565_IC_JMJD6

Organism:
Homo sapiens
Source name:
Primary Patient Derived Tumor Model
Platform:
GPL18573
Series:
GSE74520 GSE74529
Download data: BED, TDF
Sample
Accession:
GSM2360990
ID:
302360990

SRA Run Selector

12.

3565_IC_H3K27Ac

Organism:
Homo sapiens
Source name:
Primary Patient Derived Tumor Model
Platform:
GPL18573
Series:
GSE74520 GSE74529
Download data: BED, TDF
Sample
Accession:
GSM2360989
ID:
302360989

SRA Run Selector

13.

3565_IC_H3K27Ac input

Organism:
Homo sapiens
Source name:
Primary Patient Derived Tumor Model
Platform:
GPL18573
Series:
GSE74520 GSE74529
Download data
Sample
Accession:
GSM2360988
ID:
302360988

SRA Run Selector

14.

IN528culture input

Organism:
Homo sapiens
Source name:
Primary Patient Derived Tumor Model
Platform:
GPL18573
Series:
GSE74520 GSE74529
Download data
Sample
Accession:
GSM1922080
ID:
301922080

SRA Run Selector

15.

IN528culture JMJD6

Organism:
Homo sapiens
Source name:
Primary Patient Derived Tumor Model
Platform:
GPL18573
Series:
GSE74520 GSE74529
Download data: BED, BIGWIG
Sample
Accession:
GSM1922079
ID:
301922079

SRA Run Selector

16.

IN528culture H3K27Ac

Organism:
Homo sapiens
Source name:
Primary Patient Derived Tumor Model
Platform:
GPL18573
Series:
GSE74520 GSE74529
Download data: BED, BIGWIG
Sample
Accession:
GSM1922078
ID:
301922078

SRA Run Selector

17.

IN528ic input

Organism:
Homo sapiens
Source name:
Primary Patient Derived Tumor Model
Platform:
GPL18573
Series:
GSE74520 GSE74529
Download data
Sample
Accession:
GSM1922077
ID:
301922077

SRA Run Selector

18.

IN528ic JMJD6

Organism:
Homo sapiens
Source name:
Primary Patient Derived Tumor Model
Platform:
GPL18573
Series:
GSE74520 GSE74529
Download data: BED, BIGWIG
Sample
Accession:
GSM1922076
ID:
301922076

SRA Run Selector

19.

IN528ic H3K27Ac

Organism:
Homo sapiens
Source name:
Primary Patient Derived Tumor Model
Platform:
GPL18573
Series:
GSE74520 GSE74529
Download data: BED, BIGWIG
Sample
Accession:
GSM1922075
ID:
301922075

SRA Run Selector

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