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Items: 8

1.

Gene expression profiling of the MLL-AF9 induced AML cells (wild type and Dnmt3b-KO)

(Submitter supplied) Acute myeloid leukemia (AML) is a heterogeneous hematopoietic disorder with a poor prognosis. Abnormal DNA methylation is involved in the initiation and development of AML. The de novo methyltransferases Dnmt3a and Dnmt3b are responsible for the generation of genomic methylation patterns. While DNMT3A is frequently mutated in hematologic malignancies, DNMT3B is rarely mutated. To investigate the role of Dnmt3b in AML, we genetically inactivated Dnmt3b in an MLL-AF9 induced AML mouse model. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL20775
6 Samples
Download data: CEL
Series
Accession:
GSE75401
ID:
200075401
2.

[MTA-1_0] Affymetrix Mouse Transcriptome Array 1.0 [transcript (gene) CSV version]

(Submitter supplied) Annotation was derived from the Affymetrix annotation file MTA-1_0.na35.mm10.transcript.csv: #%create_date=Wed Apr 1 16:56:09 2015 PDT #%chip_type=MTA-1_0 #%lib_set_name=MTA-1_0 #%lib_set_version=r1 #%genome-species=Mus musculus #%genome-version=mm10 #%genome-version-ucsc=mm10 #%genome-version-ncbi=38 #%genome-version-create_date=2011-12-00 #%genome-lifted-method=psl-map.pl #%genome-lifted_from-species=Mus musculus #%genome-lifted_from-version-ucsc=mm10 #%genome-lifted_from-version-ncbi=38 #%netaffx-annotation-date=2014-10-31 #%netaffx-annotation-netaffx-build=35 Protocol: See manufacturers website
Organism:
Mus musculus
201 Series
2 Related Platforms
2254 Samples
Download data
Platform
Accession:
GPL20775
ID:
100020775
3.

Dnmt3b-KO AML replicate 3

Organism:
Mus musculus
Source name:
bone marrow, MLL-AF9 induced AML cells, Dnmt3b KO
Platform:
GPL20775
Series:
GSE75401
Download data: CEL
Sample
Accession:
GSM1954463
ID:
301954463
4.

Dnmt3b-KO AML replicate 2

Organism:
Mus musculus
Source name:
bone marrow, MLL-AF9 induced AML cells, Dnmt3b KO
Platform:
GPL20775
Series:
GSE75401
Download data: CEL
Sample
Accession:
GSM1954462
ID:
301954462
5.

Dnmt3b-KO AML replicate 1

Organism:
Mus musculus
Source name:
bone marrow, MLL-AF9 induced AML cells, Dnmt3b KO
Platform:
GPL20775
Series:
GSE75401
Download data: CEL
Sample
Accession:
GSM1954461
ID:
301954461
6.

Control AML replicate 3

Organism:
Mus musculus
Source name:
bone marrow, MLL-AF9 induced AML cells, littermate control
Platform:
GPL20775
Series:
GSE75401
Download data: CEL
Sample
Accession:
GSM1954460
ID:
301954460
7.

Control AML replicate 2

Organism:
Mus musculus
Source name:
bone marrow, MLL-AF9 induced AML cells, littermate control
Platform:
GPL20775
Series:
GSE75401
Download data: CEL
Sample
Accession:
GSM1954459
ID:
301954459
8.

Control AML replicate 1

Organism:
Mus musculus
Source name:
bone marrow, MLL-AF9 induced AML cells, littermate control
Platform:
GPL20775
Series:
GSE75401
Download data: CEL
Sample
Accession:
GSM1954458
ID:
301954458
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Supplemental Content

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