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Items: 14

1.

RNA-seq Profiles in RBPJ Maintains Brain Tumor Initiating Cells through CDK9-mediated Transcriptional Elongation

(Submitter supplied) Glioblastomas coopt stem cell regulatory pathways to maintain brain tumor initiating cells (BTICs), also known as cancer stem cells. Notch signaling has been a molecular target in BTICs, but Notch antagonists have demonstrated limited efficacy in clinical trials. RBPJ is considered a central transcriptional mediator of Notch activity. Here, we report that pharmacologic Notch inhibitors were less effective than targeting RBPJ in suppressing tumor growth. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL16791
12 Samples
Download data: TXT
Series
Accession:
GSE79735
ID:
200079735

PubMed Full text in PMC Similar studies Analyze with GEO2RSRA Run Selector

2.

Illumina HiSeq 2500 (Homo sapiens)

Organism:
Homo sapiens
12302 Series
351173 Samples
Download data
Platform
Accession:
GPL16791
ID:
100016791

3.

4121_DAPT_shRBPJ-2

Organism:
Homo sapiens
Source name:
Primary Patient Derived Tumor Model
Platform:
GPL16791
Series:
GSE79735 GSE79736
Download data
Sample
Accession:
GSM2101781
ID:
302101781

SRA Run Selector

4.

4121_DAPT_shRBPJ-1

Organism:
Homo sapiens
Source name:
Primary Patient Derived Tumor Model
Platform:
GPL16791
Series:
GSE79735 GSE79736
Download data
Sample
Accession:
GSM2101780
ID:
302101780

SRA Run Selector

5.

4121_DAPT_NT

Organism:
Homo sapiens
Source name:
Primary Patient Derived Tumor Model
Platform:
GPL16791
Series:
GSE79735 GSE79736
Download data
Sample
Accession:
GSM2101779
ID:
302101779

SRA Run Selector

6.

4121_DMSO_shRBPJ-2

Organism:
Homo sapiens
Source name:
Primary Patient Derived Tumor Model
Platform:
GPL16791
Series:
GSE79735 GSE79736
Download data
Sample
Accession:
GSM2101778
ID:
302101778

SRA Run Selector

7.

4121_DMSO_shRBPJ-1

Organism:
Homo sapiens
Source name:
Primary Patient Derived Tumor Model
Platform:
GPL16791
Series:
GSE79735 GSE79736
Download data
Sample
Accession:
GSM2101777
ID:
302101777

SRA Run Selector

8.

4121_DMSO_NT

Organism:
Homo sapiens
Source name:
Primary Patient Derived Tumor Model
Platform:
GPL16791
Series:
GSE79735 GSE79736
Download data
Sample
Accession:
GSM2101776
ID:
302101776

SRA Run Selector

9.

3691_DAPT_10um

Organism:
Homo sapiens
Source name:
Primary Patient Derived Tumor Model
Platform:
GPL16791
Series:
GSE79735 GSE79736
Download data
Sample
Accession:
GSM2101775
ID:
302101775

SRA Run Selector

10.

3691_DAPT_5um

Organism:
Homo sapiens
Source name:
Primary Patient Derived Tumor Model
Platform:
GPL16791
Series:
GSE79735 GSE79736
Download data
Sample
Accession:
GSM2101774
ID:
302101774

SRA Run Selector

11.

3691_DMSO

Organism:
Homo sapiens
Source name:
Primary Patient Derived Tumor Model
Platform:
GPL16791
Series:
GSE79735 GSE79736
Download data
Sample
Accession:
GSM2101773
ID:
302101773

SRA Run Selector

12.

3691_shRBPJ-2

Organism:
Homo sapiens
Source name:
Primary Patient Derived Tumor Model
Platform:
GPL16791
Series:
GSE79735 GSE79736
Download data
Sample
Accession:
GSM2101772
ID:
302101772

SRA Run Selector

13.

3691_shRBPJ-1

Organism:
Homo sapiens
Source name:
Primary Patient Derived Tumor Model
Platform:
GPL16791
Series:
GSE79735 GSE79736
Download data
Sample
Accession:
GSM2101771
ID:
302101771

SRA Run Selector

14.

3691_NT

Organism:
Homo sapiens
Source name:
Primary Patient Derived Tumor Model
Platform:
GPL16791
Series:
GSE79735 GSE79736
Download data
Sample
Accession:
GSM2101770
ID:
302101770

SRA Run Selector

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