GSE97133[Accession] - GEO DataSets

Select item 2000971331.

The B-cell receptor confers super competitor status to lymphoma cells via GSK3β inhibition II

(Submitter supplied) Similar to resting mature B cells, where the B-cell antigen receptor (BCR) is essential for cellular survival, surface BCR expression is conserved in most mature B cell lymphomas. The identification of activating BCR mutations and the growth disadvantage upon BCR knockdown of cells of certain lymphoma entities has led to the view that BCR signaling is required for tumour cell survival. Consequently, the BCR signaling machinery has become a new target in the therapy of B cell malignancies. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL11533
12 Samples

Download data: CEL

Series

Accession:: GSE97133

ID:: 200097133

Select item 1000115332.

[MoGene-1_1-st] Affymetrix Mouse Gene 1.1 ST Array [transcript (gene) version]

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html MoGene-1_1-st-v1.na31.mm9.transcript.csv #%create_date=Fri Aug 27 17:50:02 2010 PDT #%chip_type=MoGene-1_1-st-v1 #%lib_set_name=MoGene-1_1-st #%lib_set_version=v1 #%genome-species=Mus musculus #%genome-version=mm9 #%genome-version-ucsc=mm9 #%genome-version-ncbi=37 #%genome-version-create_date=2007-07-00 #%genome-lifted-method=liftOver #%genome-lifted_from-species=Mus musculus #%genome-lifted_from-version-ucsc=mm8 #%genome-lifted_from-version-ncbi=36 #%netaffx-annotation-date=2010-07-15 #%netaffx-annotation-netaffx-build=31 Protocol: see manufacturer's web site

Organism:: Mus musculus

10 DataSets
174 Series
7 Related Platforms
4230 Samples

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Platform

Accession:: GPL11533

ID:: 100011533

Select item 3025521033.

Lymphoma BCR-negative (ID # 2676) - CHIR99021 treated

Organism:: Mus musculus

Source name:: BCR-negative lymphoma B cells purified from a BCR+/BCR- mixed lymphoma cell culture grown for four days in the presence of CHIR99021

Platform:: GPL11533
Series:: GSE97133 GSE97134

Download data: CEL

Sample

Accession:: GSM2552103

ID:: 302552103

Select item 3025521024.

Lymphoma BCR-independent (ID # 2676, clone 1) - Untreated

Organism:: Mus musculus

Source name:: BCR-independent lymphoma B cells purified from a BCR+/BCR-independent mixed lymphoma cell culture grown for four days

Platform:: GPL11533
Series:: GSE97133 GSE97134

Download data: CEL

Sample

Accession:: GSM2552102

ID:: 302552102

Select item 3025521015.

Lymphoma BCR-negative (ID # 2676) - Untreated (2)

Organism:: Mus musculus

Source name:: BCR-negative lymphoma B cells purified from a BCR+/BCR- mixed lymphoma cell culture grown for four days

Platform:: GPL11533
Series:: GSE97133 GSE97134

Download data: CEL

Sample

Accession:: GSM2552101

ID:: 302552101

Select item 3025521006.

Lymphoma BCR-positive (ID # 2676) - Untreated (2)

Organism:: Mus musculus

Source name:: BCR-positive lymphoma B cells purified from a BCR+/BCR- mixed lymphoma cell culture grown for four days

Platform:: GPL11533
Series:: GSE97133 GSE97134

Download data: CEL

Sample

Accession:: GSM2552100

ID:: 302552100

Select item 3025520997.

Lymphoma BCR-negative (ID # 2646) - CHIR99021 treated

Organism:: Mus musculus

Source name:: BCR-negative lymphoma B cells purified from a BCR+/BCR- mixed lymphoma cell culture grown for four days in the presence of CHIR99021

Platform:: GPL11533
Series:: GSE97133 GSE97134

Download data: CEL

Sample

Accession:: GSM2552099

ID:: 302552099

Select item 3025520988.

Lymphoma BCR-independent (ID # 2646, clone 7) - Untreated

Organism:: Mus musculus

Source name:: BCR-independent lymphoma B cells purified from a BCR+/BCR-independent mixed lymphoma cell culture grown for four days

Platform:: GPL11533
Series:: GSE97133 GSE97134

Download data: CEL

Sample

Accession:: GSM2552098

ID:: 302552098

Select item 3025520979.

Lymphoma BCR-negative (ID # 2646) - Untreated (2)

Organism:: Mus musculus

Source name:: BCR-negative lymphoma B cells purified from a BCR+/BCR- mixed lymphoma cell culture grown for four days

Platform:: GPL11533
Series:: GSE97133 GSE97134

Download data: CEL

Sample

Accession:: GSM2552097

ID:: 302552097

Select item 30255209610.

Lymphoma BCR-positive (ID # 2646) - Untreated (2)

Organism:: Mus musculus

Source name:: BCR-positive lymphoma B cells purified from a BCR+/BCR- mixed lymphoma cell culture grown for four days

Platform:: GPL11533
Series:: GSE97133 GSE97134

Download data: CEL

Sample

Accession:: GSM2552096

ID:: 302552096

Select item 30255209511.

Lymphoma BCR-negative (ID # 2567) - CHIR99021 treated

Organism:: Mus musculus

Source name:: BCR-negative lymphoma B cells purified from a BCR+/BCR- mixed lymphoma cell culture grown for four days in the presence of CHIR99021